Detalhe da pesquisa
1.
Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro.
Nat Immunol
; 24(8): 1382-1390, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37500887
2.
Genetic variation in human DNA replication timing.
Cell
; 159(5): 1015-1026, 2014 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25416942
3.
Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines.
Cell
; 144(3): 439-52, 2011 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21295703
4.
C9orf72 suppresses systemic and neural inflammation induced by gut bacteria.
Nature
; 582(7810): 89-94, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32483373
5.
The C9orf72-interacting protein Smcr8 is a negative regulator of autoimmunity and lysosomal exocytosis.
Genes Dev
; 32(13-14): 929-943, 2018 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29950492
6.
Cx43 hemichannels contribute to astrocyte-mediated toxicity in sporadic and familial ALS.
Proc Natl Acad Sci U S A
; 119(13): e2107391119, 2022 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35312356
7.
Biallelic loss-of-function variants in CACHD1 cause a novel neurodevelopmental syndrome with facial dysmorphism and multisystem congenital abnormalities.
Genet Med
; 26(4): 101057, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38158856
8.
CSMD1 regulates brain complement activity and circuit development.
Brain Behav Immun
; 119: 317-332, 2024 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38552925
9.
Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations.
Nature
; 545(7653): 229-233, 2017 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28445466
10.
Evaluating the state of the science for adeno-associated virus integration: An integrated perspective.
Mol Ther
; 30(8): 2646-2663, 2022 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35690906
11.
RNA-seq as a tool for evaluating human embryo competence.
Genome Res
; 29(10): 1705-1718, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31548358
12.
SnapShot: directed differentiation of pluripotent stem cells.
Cell
; 149(5): 1174-1174.e1, 2012 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22632979
13.
Comparative genomic analysis of embryonic, lineage-converted and stem cell-derived motor neurons.
Development
; 145(22)2018 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30337375
14.
All-optical synaptic electrophysiology probes mechanism of ketamine-induced disinhibition.
Nat Methods
; 15(10): 823-831, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30275587
15.
Mediators of reprogramming: transcription factors and transitions through mitosis.
Nat Rev Mol Cell Biol
; 9(7): 505-16, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18568039
16.
DNA methylation dynamics of the human preimplantation embryo.
Nature
; 511(7511): 611-5, 2014 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-25079558
17.
A Stem Cell-Based Screening Platform Identifies Compounds that Desensitize Motor Neurons to Endoplasmic Reticulum Stress.
Mol Ther
; 27(1): 87-101, 2019 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30446391
18.
CLP1 links tRNA metabolism to progressive motor-neuron loss.
Nature
; 495(7442): 474-80, 2013 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23474986
19.
Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage.
Proc Natl Acad Sci U S A
; 113(48): E7701-E7709, 2016 11 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-27849576
20.
SLC52A3, A Brown-Vialetto-van Laere syndrome candidate gene is essential for mouse development, but dispensable for motor neuron differentiation.
Hum Mol Genet
; 25(9): 1814-23, 2016 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26976849