Detalhe da pesquisa
1.
Preclinical safety assessment of JNJ-10450232 (NTM-006), a structural analog of acetaminophen, that does not cause hepatotoxicity at supratherapeutic doses.
Regul Toxicol Pharmacol
; : 105334, 2023 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36608923
2.
Metabolism and disposition of JNJ-10450232 (NTM-006) in rats, dogs, monkeys and humans.
Regul Toxicol Pharmacol
; : 105379, 2023 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36931586
3.
First-in-human study to evaluate the safety, tolerability and pharmacokinetics of a novel analgesic and antipyretic drug with structural similarity to acetaminophen.
Regul Toxicol Pharmacol
; 134: 105236, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35934140