Detalhe da pesquisa
1.
The P2Y6 receptor signals through Gαq /Ca2+ /PKCα and Gα13 /ROCK pathways to drive the formation of membrane protrusions and dictate cell migration.
J Cell Physiol
; 235(12): 9676-9690, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32420639
2.
Use of a Noninvasive Brain-Penetrating Peptide-Drug Conjugate Strategy to Improve the Delivery of Opioid Pain Relief Medications to the Brain.
J Pharmacol Exp Ther
; 374(1): 52-61, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32327529
3.
Chemical space screening around Phe3 in opioid peptides: Modulating µ versus δ agonism by Suzuki-Miyaura cross-couplings.
Bioorg Med Chem Lett
; 28(13): 2320-2323, 2018 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29853330
4.
Tweak regulates astrogliosis, microgliosis and skeletal muscle atrophy in a mouse model of amyotrophic lateral sclerosis.
Hum Mol Genet
; 24(12): 3440-56, 2015 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25765661
5.
Corrigendum to "Chemical space screening around Phe3 in opioid peptides: Modulating µ versus δ agonism by Suzuki-Miyaura cross-couplings" [Bioorg. Med. Chem. Lett. 28(13) (2018) 2320-2323].
Bioorg Med Chem Lett
; 28(20): 3418, 2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30195888
6.
Ligand-dependent intracellular trafficking of the G protein-coupled P2Y6 receptor.
Biochim Biophys Acta Mol Cell Res
; 1870(5): 119476, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37059189
7.
Optimized Opioid-Neurotensin Multitarget Peptides: From Design to Structure-Activity Relationship Studies.
J Med Chem
; 63(21): 12929-12941, 2020 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32902268
8.
The combination of opioid and neurotensin receptor agonists improves their analgesic/adverse effect ratio.
Eur J Pharmacol
; 848: 80-87, 2019 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30707956
9.
Neurotensin Analogues Containing Cyclic Surrogates of Tyrosine at Position 11 Improve NTS2 Selectivity Leading to Analgesia without Hypotension and Hypothermia.
ACS Chem Neurosci
; 10(11): 4535-4544, 2019 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31589400
10.
χ-Space Screening of Dermorphin-Based Tetrapeptides through Use of Constrained Arylazepinone and Quinolinone Scaffolds.
ACS Med Chem Lett
; 8(11): 1177-1182, 2017 Nov 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29152051