Detalhe da pesquisa
1.
ß-Arrestin-2 mediates the proinflammatory effects of proteinase-activated receptor-2 in the airway.
Proc Natl Acad Sci U S A
; 109(41): 16660-5, 2012 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23012429
2.
Nebulized perflubron and carbon dioxide rapidly dilate constricted airways in an ovine model of allergic asthma.
Respir Res
; 15: 98, 2014 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25355286
3.
Mucosal allergic sensitization to cockroach allergens is dependent on proteinase activity and proteinase-activated receptor-2 activation.
J Immunol
; 186(5): 3164-72, 2011 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21270400
4.
Carbon dioxide enhances substance P-induced epithelium-dependent bronchial smooth muscle relaxation in Sprague-Dawley rats.
Can J Physiol Pharmacol
; 89(7): 513-20, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21812529
5.
A phase IIa proof-of-concept, placebo-controlled, randomized, double-blind, crossover, single-dose clinical trial of a new class of bronchodilator for acute asthma.
Trials
; 19(1): 321, 2018 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29914544
6.
A phase I, placebo-controlled, randomized, double-blind, single ascending dose-ranging study to evaluate the safety and tolerability of a novel biophysical bronchodilator (S-1226) administered by nebulization in healthy volunteers.
Trials
; 17: 361, 2016 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27464582