Detalhe da pesquisa
1.
VPS35 and the mitochondria: Connecting the dots in Parkinson's disease pathophysiology.
Neurobiol Dis
; 145: 105056, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32853677
2.
A de novo compound targeting α-synuclein improves deficits in models of Parkinson's disease.
Brain
; 139(Pt 12): 3217-3236, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27679481
3.
HIV-1 Tat alters neuronal autophagy by modulating autophagosome fusion to the lysosome: implications for HIV-associated neurocognitive disorders.
J Neurosci
; 35(5): 1921-38, 2015 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-25653352
4.
Novel therapeutic strategy for neurodegeneration by blocking Aß seeding mediated aggregation in models of Alzheimer's disease.
Neurobiol Dis
; 74: 144-57, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25173807
5.
ESCRT-mediated uptake and degradation of brain-targeted α-synuclein single chain antibody attenuates neuronal degeneration in vivo.
Mol Ther
; 22(10): 1753-67, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25008355
6.
Retromer stabilization using a pharmacological chaperone protects in an α-synuclein based mouse model of Parkinson's.
Res Sq
; 2023 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37886523
7.
Ferroptosis in Parkinson's disease: Molecular mechanisms and therapeutic potential.
Ageing Res Rev
; 91: 102077, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37742785
8.
Knockout or inhibition of USP30 protects dopaminergic neurons in a Parkinson's disease mouse model.
Nat Commun
; 14(1): 7295, 2023 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37957154
9.
Entacapone and tolcapone, two catechol O-methyltransferase inhibitors, block fibril formation of alpha-synuclein and beta-amyloid and protect against amyloid-induced toxicity.
J Biol Chem
; 285(20): 14941-14954, 2010 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-20150427
10.
Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis.
Nat Commun
; 11(1): 3848, 2020 07 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-32737286
11.
Neuroprotection of microglial conditioned medium on 6-hydroxydopamine-induced neuronal death: role of transforming growth factor beta-2.
J Neurochem
; 110(2): 545-56, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19457129
12.
VPS35-Based Approach: A Potential Innovative Treatment in Parkinson's Disease.
Front Neurol
; 10: 1272, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31920908
13.
Neuroprotection of microglia conditioned media from apoptotic death induced by staurosporine and glutamate in cultures of rat cerebellar granule cells.
Neurosci Lett
; 448(1): 74-8, 2008 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-18950681
14.
Parkinson's Disease Genes VPS35 and EIF4G1 Interact Genetically and Converge on α-Synuclein.
Neuron
; 111(1): 138, 2023 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36603548
15.
Editorial: Prion and prion-like proteins in neurodegenerative diseases.
Front Neurosci
; 16: 1073218, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36408386
16.
Parkinson's disease genes VPS35 and EIF4G1 interact genetically and converge on α-synuclein.
Neuron
; 85(1): 76-87, 2015 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25533483
17.
Chronic dietary administration of valproic acid protects neurons of the rat nucleus basalis magnocellularis from ibotenic acid neurotoxicity.
Neurotox Res
; 15(2): 127-32, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19384575