Detalhe da pesquisa
1.
Myeloid LXR (Liver X Receptor) Deficiency Induces Inflammatory Gene Expression in Foamy Macrophages and Accelerates Atherosclerosis.
Arterioscler Thromb Vasc Biol
; 42(6): 719-731, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35477277
2.
Oxidized Phospholipids Promote NETosis and Arterial Thrombosis in LNK(SH2B3) Deficiency.
Circulation
; 144(24): 1940-1954, 2021 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34846914
3.
Increased SLAMF7high monocytes in myelofibrosis patients harboring JAK2V617F provide a therapeutic target of elotuzumab.
Blood
; 134(10): 814-825, 2019 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31270105
4.
Liver X Receptors Regulate Cholesterol Metabolism and Immunity in Hepatic Nonparenchymal Cells.
Int J Mol Sci
; 20(20)2019 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31614590
5.
Synthesis and In Vitro Evaluation of Novel Liver X Receptor Agonists Based on Naphthoquinone Derivatives.
Molecules
; 24(23)2019 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31779181
6.
Structural development of tetrachlorophthalimides as liver X receptor ß (LXRß)-selective agonists with improved aqueous solubility.
Bioorg Med Chem Lett
; 28(4): 796-801, 2018 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29398545
7.
Activation of LXRs using the synthetic agonist GW3965 represses the production of pro-inflammatory cytokines by murine mast cells.
Allergol Int
; 64 Suppl: S11-7, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26344074
8.
Protective effect of S-allyl-L-cysteine against endoplasmic reticulum stress-induced neuronal death is mediated by inhibition of calpain.
Amino Acids
; 46(2): 385-93, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24287800
9.
Cholesterol accumulation in macrophages drives NETosis in atherosclerotic plaques via IL-1ß secretion.
Cardiovasc Res
; 119(4): 969-981, 2023 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36537208
10.
Differential expression and function of alternative splicing variants of human liver X receptor α.
Mol Pharmacol
; 81(6): 800-10, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22399489
11.
Vitamin D receptor activation enhances benzo[a]pyrene metabolism via CYP1A1 expression in macrophages.
Drug Metab Dispos
; 40(11): 2059-66, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22837390
12.
Hairless modulates ligand-dependent activation of the vitamin D receptor-retinoid X receptor heterodimer.
Biol Pharm Bull
; 35(4): 582-7, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22466564
13.
Erythroid lineage Jak2V617F expression promotes atherosclerosis through erythrophagocytosis and macrophage ferroptosis.
J Clin Invest
; 132(13)2022 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35587375
14.
Contrasting functional responses of resident Kupffer cells and recruited liver macrophages to irradiation and liver X receptor stimulation.
PLoS One
; 16(7): e0254886, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34297734
15.
Liver X receptors regulate natural killer T cell population and antitumor activity in the liver of mice.
Sci Rep
; 11(1): 22595, 2021 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34799646
16.
Frontline Science: Concanavalin A-induced acute hepatitis is attenuated in vitamin D receptor knockout mice with decreased immune cell function.
J Leukoc Biol
; 106(4): 791-801, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31034649
17.
Dysregulation of Kupffer Cells/Macrophages and Natural Killer T Cells in Steatohepatitis in LXRα Knockout Male Mice.
Endocrinology
; 159(3): 1419-1432, 2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29409022
18.
Liver X receptors regulate hepatic F4/80 + CD11b+ Kupffer cells/macrophages and innate immune responses in mice.
Sci Rep
; 8(1): 9281, 2018 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29915246
19.
1α-Hydroxy derivatives of 7-dehydrocholesterol are selective liver X receptor modulators.
J Steroid Biochem Mol Biol
; 172: 136-148, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28736297
20.
Development of Tetrachlorophthalimides as Liverâ X Receptorâ ß (LXRß)-Selective Agonists.
ChemMedChem
; 11(20): 2347-2360, 2016 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27690261