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1.
Public Health ; 230: 89-95, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38521029

RESUMO

OBJECTIVES: This study aims to assess exposure to e-cigarette advertising across multiple marketing channels among U.S. youth and to examine whether racial/ethnic disparities exist in exposure to e-cigarette advertisements. STUDY DESIGN: This is a cross-sectional study. METHODS: Cross-sectional data were drawn from a longitudinal survey of participants recruited from two nationally representative panels (NORC's AmeriSpeak® and GfK's KnowledgePanel). A total of 2043 youth aged 13-17 completed the initial 2018 survey, and 2013 youth completed the follow-up survey in 2019 (including a replenishment sample of 690 youth). Outcome variables were self-reported e-cigarette advertisement exposure in the past three months through various sources, such as television, point of sale, and online/social media. Generalized estimating equation models were used to estimate the adjusted odds ratios (AOR) of the association between racial/ethnic identity and e-cigarette advertisement exposure. RESULTS: The prevalence of reported exposure to e-cigarette advertisements through any channel was 79.8% (95% CI: 77.1-82.2) in 2018 and 74.9% (95% CI: 72.5-77.1) in 2019, respectively. Point of sale was the most common source of e-cigarette advertisement exposure in both years. Non-Hispanic Black and non-Hispanic Asian youth were more likely to report exposure to e-cigarette advertisements through television (AOR = 2.07, 95% CI: 1.44-2.99 and AOR = 2.11, 95% CI: 1.17-3.82, respectively) and online/social media (AOR = 1.61; 95% CI: 1.11-2.33 and AOR = 1.99, 95% CI: 1.10-3.59, respectively) channels compared with non-Hispanic White youth. CONCLUSIONS: A substantial proportion of U.S. youth reported exposure to e-cigarette advertising through a variety of marketing channels. Significant racial/ethnic disparities existed, with non-Hispanic Black and Asian youth reporting more marketing exposure than their non-Hispanic White counterparts.


Assuntos
Sistemas Eletrônicos de Liberação de Nicotina , Produtos do Tabaco , Humanos , Adolescente , Publicidade , Estudos Transversais , Marketing
2.
Surg Endosc ; 33(9): 2821-2833, 2019 09.
Artigo em Inglês | MEDLINE | ID: mdl-30413929

RESUMO

BACKGROUND: To describe the real burden of major complications after elective surgery for colon cancer in Norway, and to assess which predictors that are significantly associated with the short-term outcome. METHODS: An observational, multi-centre analysis of prospectively registered colon resections registered into the Norwegian Registry for Gastrointestinal Surgery, NoRGast, between January 2014 and December 2016. A propensity score-adjusted subgroup analysis for surgical access groups was attempted, with laparoscopic resections grouped as intention-to-treat. RESULTS: Out of 1812 resections, 14.0% of patients experienced a major complication within 30 days following surgery. The over-all reoperation rate was 8.7%, and rate of reoperation for anastomotic leak was 3.8%. Twenty patients (1.1%) died within 30 days after surgery. Higher age was not a significant predictor of major complications, including 30-day mortality. After correction for all co-variables, open access surgery was associated with higher rates of major complications (OR 1.67 (CI 1.22-2.29), p = 0.002), higher 30-day mortality (OR 4.39 (CI 1.19-16.13) p = 0.026) and longer length-of-stay (HR 0.58 (CI 0.52-0.65) p < 0.001). CONCLUSIONS: Our results indicate a low complication burden and high rate of uneventful patient journeys after elective surgery for colon cancer in Norway. Age was not associated with higher morbidity or mortality rates. Open access surgery was associated with an inferior short-term outcome.


Assuntos
Colectomia , Neoplasias do Colo/cirurgia , Procedimentos Cirúrgicos Eletivos , Laparoscopia , Complicações Pós-Operatórias , Idoso , Colectomia/efeitos adversos , Colectomia/métodos , Neoplasias do Colo/epidemiologia , Procedimentos Cirúrgicos Eletivos/efeitos adversos , Procedimentos Cirúrgicos Eletivos/métodos , Feminino , Humanos , Laparoscopia/efeitos adversos , Laparoscopia/métodos , Masculino , Pessoa de Meia-Idade , Noruega/epidemiologia , Avaliação de Processos e Resultados em Cuidados de Saúde , Complicações Pós-Operatórias/etiologia , Complicações Pós-Operatórias/mortalidade , Sistema de Registros/estatística & dados numéricos , Reoperação/estatística & dados numéricos
3.
J Clin Monit Comput ; 28(1): 67-74, 2014 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-23881418

RESUMO

During resting tidal breathing the shape of the expiratory airflow waveform differs with age and respiratory disease. While most studies quantifying these changes report time or volume specific metrics, few have concentrated on waveform shape or area parameters. The aim of this study was to derive and compare the centroid co-ordinates (the geometric centre) of inspiratory and expiratory flow-time and flow-volume waveforms collected from participants with or without COPD. The study does not aim to test the diagnostic potential of these metrics as an age matched control group would be required. Twenty-four participants with COPD and thirteen healthy participants who underwent spirometry had their resting tidal breathing recorded. The flow-time data was analysed using a Monte Carlo simulation to derive the inspiratory and expiratory flow-time and flow-volume centroid for each breath. A comparison of airflow waveforms show that in COPD, the breathing rate is faster (17 ± 4 vs 14 ± 3 min(-1)) and the time to reach peak expiratory flow shorter (0.6 ± 0.2 and 1.0 ± 0.4 s). The expiratory flow-time and flow-volume centroid is left-shifted with the increasing asymmetry of the expired airflow pattern induced by airway obstruction. This study shows that the degree of skew in expiratory airflow waveforms can be quantified using centroids.


Assuntos
Doença Pulmonar Obstrutiva Crônica/fisiopatologia , Respiração , Volume de Ventilação Pulmonar , Adolescente , Adulto , Obstrução das Vias Respiratórias , Expiração , Feminino , Humanos , Inalação , Masculino , Modelos Teóricos , Método de Monte Carlo , Projetos Piloto , Ventilação Pulmonar , Sistema de Registros , Reprodutibilidade dos Testes , Espirometria/métodos , Adulto Jovem
4.
Colorectal Dis ; 15(6): e301-8, 2013 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-23582027

RESUMO

AIM: Evaluation of ≥ 12 lymph nodes (LNs) is recommended after surgery for colon cancer. A harvest of ≤ 8 is considered poor, but few reports have evaluated risk factors associated with a poor harvest. This aims of this study were to analyse the clinical, surgical and pathological factors associated with poor LN harvest (LNH), the total number of examined nodes and the effect of LN number on stage. METHOD: All patients reported to the Norwegian Colorectal Cancer Registry during 2007 and 2008 who underwent curative resection for Stage I-III colon cancer were studied. Risk factors for poor LNH and the proportion of Stage III disease were analysed by univariate and multivariate analyses. RESULTS: A total of 2879 patients were included in the study. The median LNH was 14. Overall, 69.9% had ≥ 12 lymph nodes and 14.4% had ≤ 8 LN (poor harvest). Multivariate analysis showed that male sex, age > 75 years, sigmoid tumours, pT category 1-2, failure to use the pathology report template and distance of ≤ 5 cm from the bowel resection margin were all independent factors for poor LNH. Age < 65 years, pT category 3-4, and poor tumour differentiation were independent predictors of Stage III disease. An increased LNH did not increase the proportion of patients identified as being LN positive at the ≤ 8, 9-11 and ≥ 12 LN levels. CONCLUSION: Adequate LNH was achieved in the majority of curative colon cancer resections in this national cohort. Elderly, male patients with sigmoid cancers, and a short distal margin were at increased risk of a poor LNH.


Assuntos
Adenocarcinoma/patologia , Neoplasias do Colo/patologia , Excisão de Linfonodo/estatística & dados numéricos , Linfonodos/patologia , Adenocarcinoma/cirurgia , Fatores Etários , Idoso , Estudos de Coortes , Neoplasias do Colo/cirurgia , Feminino , Humanos , Modelos Logísticos , Excisão de Linfonodo/normas , Linfonodos/cirurgia , Masculino , Pessoa de Meia-Idade , Análise Multivariada , Estadiamento de Neoplasias , Noruega , Fatores de Risco , Fatores Sexuais , Neoplasias do Colo Sigmoide/patologia , Neoplasias do Colo Sigmoide/cirurgia
5.
Br J Surg ; 98(5): 716-23, 2011 May.
Artigo em Inglês | MEDLINE | ID: mdl-21341253

RESUMO

BACKGROUND: The surgical management of rectal cancer has changed substantially over the past decade. There are limited data on the long-term outcome of implementing systematic management strategies. METHODS: Survival of a national cohort of patients treated surgically for colonic and rectal cancer over a 10-year interval was analysed. All 31 158 patients in Norway diagnosed with adenocarcinoma of the colon and rectum between 1994 and 2003 were identified from the Cancer Registry of Norway and the Norwegian Rectal Cancer Registry. Changes in 5-year relative survival were compared by age, stage and tumour location during the early and late years. RESULTS: The study population included 19 053 patients who had a curative resection. The relative 5-year survival rate significantly improved for both colonic cancer (73·8 versus 78·0 per cent; P < 0·001) and rectal cancer (72·1 versus 79·6 per cent; P < 0·001). The 5-year relative survival was significantly better for rectal than colonic cancer during the late period (P = 0·030). Improved 5-year relative survival was related to better outcomes in patients with positive lymph nodes (67·2 and 62·1 per cent for rectal and colonic cancer respectively; each P < 0·001 versus early period), but not for the subgroup aged over 75 years with lymph node-positive colonic cancer. CONCLUSION: In this national cohort, survival after curative surgery for colorectal cancer increased significantly after implementation of national management strategies. Improvements were most evident for rectal cancer and in lymph node-positive disease; they were less substantial for colonic cancer and elderly patients (over 75 years). Strategic treatment changes may be warranted for the latter group.


Assuntos
Neoplasias do Colo/cirurgia , Neoplasias Retais/cirurgia , Adulto , Idoso , Neoplasias do Colo/mortalidade , Feminino , Humanos , Metástase Linfática , Masculino , Pessoa de Meia-Idade , Noruega/epidemiologia , Guias de Prática Clínica como Assunto , Neoplasias Retais/mortalidade , Sistema de Registros , Análise de Sobrevida , Resultado do Tratamento
6.
J Fish Biol ; 79(3): 575-86, 2011 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-21884101

RESUMO

Mature female Atlantic salmon Salmo salar were given intraperitoneal cortisol implants 1 week prior to stripping to examine the influence of simulated maternal stress on offspring boldness and social dominance. Behavioural tests originally designed to investigate stress responsiveness and coping styles in salmonids (i.e. feeding in isolation, dominance tests and acute confinement) were carried out on the offspring 1·5 years after hatching. In the feeding test, there were no differences between the two treatment groups in total feeding score or number of pellets eaten, but offspring from the cortisol-implanted females made more unsuccessful feeding attempts than offspring from control females. In dominance tests, there was no difference between controls and cortisol-treated fish regarding propensity to become socially dominant. A higher proportion of individuals with bite marks, however, was observed in the cortisol group when compared to controls. Cortisol-treated offspring that gained dominant rank in the dominance tests performed more aggressive acts after stable dominance-subordinate relationships were established compared to control winners. During acute confinement stress, offspring from cortisol-implanted females showed a reduction in the proportion of time they were moving compared to the controls. These results indicate that the maternal endocrine state at spawning affects several aspects of progeny behaviour potentially related to subsequent success and survival in farmed S. salar.


Assuntos
Aquicultura , Comportamento Competitivo , Salmo salar/fisiologia , Predomínio Social , Estresse Fisiológico , Animais , Feminino , Hidrocortisona/administração & dosagem , Hidrocortisona/análise , Hidrocortisona/sangue , Óvulo/química
7.
Scand J Public Health ; 38(1): 104-7, 2010 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-19736248

RESUMO

BACKGROUND: The objective of this study was to find out the number of publications (in Danish) and research projects (including grey literature) either carried out or ongoing within the field of public health in Denmark, using the same criteria as the SPHERE project, but looking at Danish research databases. METHODS: The Danish research database served as the main resource for the study supported by national research reports. RESULTS: There is an increasing trend in the number of public health research projects and publications. Compared with public health research projects published in English there are differences in some categories. Overall, public health research in Denmark seems to contribute around 4.8%-6.5% of the total amount of health research. CONCLUSIONS: Public health research has a relatively low share of overall health research in Denmark.


Assuntos
Saúde Pública , Pesquisa , Bases de Dados Bibliográficas , Dinamarca , Humanos , Internet , Publicações Periódicas como Assunto , Editoração , Pesquisa/estatística & dados numéricos , Pesquisa/tendências
8.
Br J Surg ; 96(10): 1176-82, 2009 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-19787766

RESUMO

BACKGROUND: The purpose of this study was to describe management and outcome in patients with locally recurrent rectal cancer based on data from the Norwegian Colorectal Cancer Registry. METHODS: This was a prospective national cohort study of 577 patients with local recurrence after major resection (R0/R1) for rectal cancer between November 1993 and December 2001 (initial cohort of 4504 patients). RESULTS: Of the 577 patients, 185 (32.1 per cent) had curative resections (R0/R1), 203 (35.2 per cent) had palliative radiotherapy with or without palliative surgery and chemotherapy, and 189 (32.8 per cent) received no treatment at all or only palliative surgery or chemotherapy. The overall 5-year survival rate was 14.9 per cent. Ninety-seven patients had an R0 resection, and 88 had an R1 resection, with 5-year overall survival of 55 and 20 per cent respectively. This outcome reflected surgical treatment in 33 different hospitals. Some 274 patients (47.5 per cent) had metastases. The 5-year survival rate after R0 resection was 62 per cent in patients without metastases. CONCLUSION: Obtaining an R0 resection is the most important prognostic factor in treating recurrent rectal cancer.


Assuntos
Recidiva Local de Neoplasia/cirurgia , Neoplasias Retais/cirurgia , Adulto , Idoso , Idoso de 80 Anos ou mais , Terapia Combinada , Intervalo Livre de Doença , Feminino , Humanos , Estimativa de Kaplan-Meier , Masculino , Pessoa de Meia-Idade , Recidiva Local de Neoplasia/tratamento farmacológico , Recidiva Local de Neoplasia/radioterapia , Noruega , Cuidados Paliativos/métodos , Cuidados Paliativos/estatística & dados numéricos , Estudos Prospectivos , Neoplasias Retais/tratamento farmacológico , Neoplasias Retais/radioterapia , Resultado do Tratamento
9.
Waste Manag ; 87: 161-172, 2019 Mar 15.
Artigo em Inglês | MEDLINE | ID: mdl-31109515

RESUMO

Recycling of plastic from household waste (HHW) is crucial in the transition towards a circular plastic economy. Plastic from HHW consists of numerous immiscible polymers, product types and product designs (e.g. colour, polymer separability), which often lead to considerable physical losses during sorting, and low-quality recycled plastic. Consequently, recycling initiatives have been proposed to enhance the quantity and quality of plastic recycling from HHW. To quantify the potential effects of such initiatives, a detailed composition of plastic waste is necessary. The aim was to provide such detailed composition of Danish source-separated rigid plastic waste, including information regarding the polymer of the main product component, product type, polymer design and separability as well as colour. The potential effects on recycled quantity and quality from implementing selected recycling initiatives were quantified and recommendations provided. PET, PE and PP made up >90% of the source-separated plastic and both food- and non-food packaging existed in all three polymers. In total, 10-11% of the plastic was black, and around 44% consisted of multiple polymers, of which one-third was non-separable. Initiatives improving product design for recycling will likely result in increased quantity of recycled plastic. By effectively separating food from non-food packaging, e.g. by introducing two bins in the households or politically aligning polymers and product types (all food packaging in PET and PP, all non-food packaging in PE), 39-63% of the waste could potentially be recycled in a closed loop into food-grade quality packaging. The overall highest benefits were reached by combining initiatives.


Assuntos
Plásticos , Reciclagem , Polímeros , Embalagem de Produtos
10.
Waste Manag ; 96: 75-85, 2019 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-31376972

RESUMO

Recycling of plastic is an important step towards circular economy. However, plastic from household waste (HHW) is a heterogeneous and contaminated resource, leading to recycled plastic with reduced quality, limiting the potential for closed-loop recycling. In addition to regulatory requirements for the chemical composition of recycled plastic, reduced physical and mechanical properties may limit the potential for closed-loop recycling. Consequently, this study analyses the thermal degradation, processability and mechanical properties of a range of reprocessed PET, PE and PP samples from source-separated plastic in HHW. On this basis, the potential for closed-loop recycling is evaluated. The study demonstrated that PET, PE and PP recycling represent different challenges. Potential degradation of the PET polymer can be reversed in a decontamination process, making PET waste well-suited for closed-loop, multiple times recycling, even when the degree of heterogeneity in the waste is high. The processability of different kinds of PE and PP packaging types varied considerably, especially for PP. Consequently, current recycling of mixed PP waste and even separate recycling of individual PP waste packaging types, will not technically facilitate recycling into new packaging products. This highlights the importance of PE and PP waste homogeneity when sent to reprocessing. Such homogeneity may be achieved through additional plastic sorting and regulatory harmonisation of product design, accounting for polymer properties and recyclability. Degradation of PP during recycling was shown to be substantial, representing another important limitation for PP recycling, necessary to address in the future.


Assuntos
Plásticos , Reciclagem , Polietilenotereftalatos , Polímeros , Embalagem de Produtos
11.
Waste Manag ; 79: 595-606, 2018 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-30343792

RESUMO

The global consumption of plastic continues to increase, and plastic recycling is highlighted as crucial for saving fossil resources and closing material loops. Plastic can be made from different polymers and contains a variety of substances, added intentionally to enhance the plastic's properties (metals added as fillers, colourants, etc.). Moreover, plastic can be contaminated during use and subsequent waste management. Consequently, if substances and contaminants are not removed during recycling, potentially problematic substances might be recycled with the targeted polymers, hence the need for quantitative data about the nature and presence of these substances in plastic. Samples of selected polymers (PET, PE, PP, PS) were collected from different origins; plastic household waste, flakes/pellets of reprocessed plastic from households and industry, and virgin plastic. Fifteen selected metals (Al, As, Cd, Co, Cr, Cu, Fe, Hg, Li, Mn, Ni, Pb, Sb, Ti, Zn) were quantified and the statistical analysis showed that both the polymer and origin influenced the metal concentration. Sb and Zn were potentially related to the production stage of PET and PS, respectively. Household plastic samples (waste and reprocessed) were found to contain significantly higher Al, Pb, Ti and Zn concentrations when compared to virgin samples. Only the concentration of Mn was reduced during washing, suggesting that parts of it was present as physical contamination. While most of the metals were below legal limit values, elevated concentrations in reprocessed plastic from households, aligned with increasing recycling rates, may lead to higher metal concentrations in the future.


Assuntos
Plásticos , Gerenciamento de Resíduos , Metais , Polímeros , Reciclagem
12.
Scand J Surg ; 107(3): 201-207, 2018 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-29628007

RESUMO

BACKGROUND AND AIMS: There is an increasing demand for high-quality data for the outcome of health care. Diseases of the gastro-intestinal tract involve large patient groups often presenting with serious or life-threatening conditions. Complications may affect treatment outcomes and lead to increased mortality or reduced quality of life. A continuous, risk-adjusted monitoring of major complications is important to improve the quality of health care to patients undergoing gastrointestinal resections. We present the development of the Norwegian Registry for Gastrointestinal Surgery, a national registry for colorectal, upper gastrointestinal, and hepato-pancreato-biliary resections in Norway. MATERIALS AND METHODS: A narrative and qualitative presentation of the development and current state of the registry. RESULTS: We present the variables and the analysis tools and provide examples for the potential in quality improvement and research. Core characteristics include a strictly limited set of variables to reflect important risk factors, the procedure performed, and the clinical outcomes. CONCLUSION: A registry with the potential to present complete national cohort data is a powerful tool for quality improvement and research.


Assuntos
Doenças do Sistema Digestório/epidemiologia , Doenças do Sistema Digestório/cirurgia , Procedimentos Cirúrgicos do Sistema Digestório/estatística & dados numéricos , Melhoria de Qualidade/estatística & dados numéricos , Sistema de Registros/estatística & dados numéricos , Humanos , Noruega/epidemiologia
13.
Lancet ; 367(9512): 749-53, 2006 Mar 04.
Artigo em Inglês | MEDLINE | ID: mdl-16517275

RESUMO

BACKGROUND: Tobacco use is a leading preventable risk factor for many chronic disorders, which are expected to account for an increasing share of the global disease burden. As part of the Global Youth Tobacco Survey (GYTS), we aimed to assess the effect of tobacco use by young people on global mortality. METHODS: GYTS is a school-based survey of students aged 13-15 years. The survey was undertaken at 395 sites in 131 countries and the Gaza Strip and West Bank. We questioned students about current tobacco use, susceptibility to smoking among non-smokers, and exposure to secondhand smoke at home and in public places. FINDINGS: The difference in current cigarette smoking between boys and girls is narrower than expected in many regions of the world. Use of tobacco products other than cigarettes by students is as high as cigarette smoking in many regions. Almost one in five never-smokers reported they were susceptible to smoking in the next year. Student exposure to secondhand smoke was high both at home (more than four in ten) and in public places (more than five in ten). Never-smokers were significantly less likely than current smokers to be exposed to secondhand smoke at home (prevalence 39.1% [95% CI 36.6-41.6] vs 72.8% [64.0-81.6]) and in public places (49.5% [46.7-52.3] vs 81.2% [74.2-88.2]). INTERPRETATION: Our findings are troubling for the future of chronic disease and tobacco-related mortality. Reduction of tobacco consumption will require a redoubling of efforts to prevent initiation and promote cessation among the large proportion of young people who currently use tobacco. High exposure to secondhand smoke suggests a need for countries to pass strong and effective smoke-free policies.


Assuntos
Saúde Global , Vigilância da População/métodos , Fumar/epidemiologia , Adolescente , Publicidade , Doença Crônica , Feminino , Humanos , Masculino , Prevalência , Distribuição por Sexo , Fumar/efeitos adversos , Inquéritos e Questionários , Poluição por Fumaça de Tabaco/estatística & dados numéricos
14.
AJNR Am J Neuroradiol ; 38(9): 1783-1788, 2017 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-28705815

RESUMO

BACKGROUND AND PURPOSE: Pulsatile tinnitus is experienced by most patients with idiopathic intracranial hypertension. The pathophysiology remains uncertain; however, transverse sinus stenosis and sigmoid sinus diverticulum/dehiscence have been proposed as potential etiologies. We aimed to determine whether the prevalence of transverse sinus stenosis and sigmoid sinus diverticulum/dehiscence was increased in patients with idiopathic intracranial hypertension and pulsatile tinnitus relative to those without pulsatile tinnitus and a control group. MATERIALS AND METHODS: CT vascular studies of patients with idiopathic intracranial hypertension with pulsatile tinnitus (n = 42), without pulsatile tinnitus (n = 37), and controls (n = 75) were independently reviewed for the presence of severe transverse sinus stenosis and sigmoid sinus diverticulum/dehiscence according to published criteria. The prevalence of transverse sinus stenosis and sigmoid sinus diverticulum/dehiscence in patients with idiopathic intracranial hypertension with pulsatile tinnitus was compared with that in the nonpulsatile tinnitus idiopathic intracranial hypertension group and the control group. Further comparisons included differing degrees of transverse sinus stenosis (50% and 75%), laterality of transverse sinus stenosis/sigmoid sinus diverticulum/dehiscence, and ipsilateral transverse sinus stenosis combined with sigmoid sinus diverticulum/dehiscence. RESULTS: Severe bilateral transverse sinus stenoses were more frequent in patients with idiopathic intracranial hypertension than in controls (P < .001), but there was no significant association between transverse sinus stenosis and pulsatile tinnitus within the idiopathic intracranial hypertension group. Sigmoid sinus dehiscence (right- or left-sided) was also more common in patients with idiopathic intracranial hypertension compared with controls (P = .01), but there was no significant association with pulsatile tinnitus within the idiopathic intracranial hypertension group. CONCLUSIONS: While our data corroborate previous studies demonstrating increased prevalence of sigmoid sinus diverticulum/dehiscence and transverse sinus stenosis in idiopathic intracranial hypertension, we did not establish an increased prevalence in patients with idiopathic intracranial hypertension with pulsatile tinnitus compared with those without. It is therefore unlikely that these entities represent a direct structural correlate of pulsatile tinnitus in patients with idiopathic intracranial hypertension.


Assuntos
Cavidades Cranianas/patologia , Pseudotumor Cerebral/complicações , Zumbido/etiologia , Idoso , Constrição Patológica/complicações , Constrição Patológica/epidemiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Pseudotumor Cerebral/patologia
15.
Prev Med Rep ; 5: 33-40, 2017 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-27896041

RESUMO

The purpose of this study is to investigate how the use of flavored e-cigarettes varies between youth (12-17 years old), young adults (18-29 years old), and older adults (30 + years old). Cross-sectional surveys of school-going youth (n = 3907) and young adult college students (n = 5482) in Texas, and young adults and older adults (n = 6051) nationwide were administered in 2014-2015. Proportions and 95% confidence intervals were used to describe the percentage of e-cigarette use at initiation and in the past 30 days that was flavored, among current e-cigarette users. Chi-square tests were applied to examine differences by combustible tobacco product use and demographic factors. Most e-cigarette users said their first and "usual" e-cigarettes were flavored. At initiation, the majority of Texas school-going youth (98%), Texas young adult college students (95%), and young adults (71.2%) nationwide said their first e-cigarettes were flavored to taste like something other than tobacco, compared to 44.1% of older adults nationwide. Fruit and candy flavors predominated for all groups; and, for youth, flavors were an especially salient reason to use e-cigarettes. Among adults, the use of tobacco flavor at initiation was common among dual users (e-cigarettes + combustible tobacco), while other flavors were more common among former cigarette smokers (P = 0.03). Restricting the range of e-cigarette flavors (e.g., eliminating sweet flavors, like fruit and candy) may benefit youth and young adult prevention efforts. However, it is unclear what impact this change would have on adult smoking cessation.

16.
J Hum Hypertens ; 20(5): 362-71, 2006 May.
Artigo em Inglês | MEDLINE | ID: mdl-16511507

RESUMO

The objective of this study was to determine the contribution of regional fat localizations defined as abdominal (AO) or truncal (TO) obesity in racial/ethnic differences to the prevalence odds of hypertension in overweight American adults. Data (n=5,694) from the 1999-2002 US National Health and Nutrition Examination Survey were utilized for this analysis. Abdominal obesity was defined as waist circumference >or=102 and >or=88 cm for men and women, respectively. Truncal obesity was defined using ratio of subscapular to triceps skinfold thickness and were >or=2.24 and >or=1.32, for men and women, respectively. Prevalence odds ratios from gender-specific logistic regression models were used to evaluate the contribution of regional fat localizations to racial/ethnic variation in hypertension. Statistical adjustment was made for age, education, alcohol intake and body mass index. In both men and women, coexistence of AO and TO was associated with much higher prevalence odds of hypertension than association due to each of the regional fat localizations. In men, coexistence of AO and TO was associated with 1.99, 2.47 and 2.10 increased prevalence odds of hypertension in Whites, Blacks and Mexican Americans, respectively. The corresponding values in women were 2.83, 4.07 and 3.61 in Whites, Blacks and Mexican Americans, respectively. The coexistence of AO and TO appears to be the culprit that contributes to high blood pressure on top of body mass index. Weight reduction programs that are targeted toward abdominal and truncal regions in at-risk populations and along racial/ethnic lines may help to alleviate racial/ethnic disparity in risk of hypertension.


Assuntos
Hipertensão/etnologia , Hipertensão/etiologia , Obesidade/complicações , Obesidade/etnologia , Abdome , Adulto , Análise de Variância , População Negra/estatística & dados numéricos , Feminino , Hispânico ou Latino/estatística & dados numéricos , Humanos , Hipertensão/epidemiologia , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Obesidade/epidemiologia , Razão de Chances , Prevalência , Fatores de Risco , Dobras Cutâneas , Estados Unidos/epidemiologia , População Branca/estatística & dados numéricos
17.
Eur J Surg Oncol ; 32(2): 174-80, 2006 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-16412603

RESUMO

AIMS: Most reports on locally advanced rectal cancer come from specialized centres, with a selected patient material. The purpose of this study was to examine the results after surgical treatment of patients with locally advanced rectal cancer at a population level. METHODS: National cohort study of 896 patients undergoing surgery for a locally advanced primary adenocarcinoma of the rectum from November 1993 to December 2001. RESULTS: Surgery with resection was undertaken in 724 patients and 172 patients underwent palliative procedures. Of 557 patients treated for cure, a R0 resection was achieved in 342 (61%). In a multivariate analysis, pre-operative radiotherapy was the only factor with a positive association with R0 status (odds ratio 3.7, 95% confidence interval (CI) 2.1-6.4). Five-year local recurrence rates were 18% (CI 14-23) for R0 resections and 40% (CI 26-52) for R1 resections. Overall 5-year survival rate was 23%; for the group of patients with a R0 resection the survival rate was 49%. CONCLUSION: The radical resection rate and survival rates in this national study were similar to those reported from specialized centres.


Assuntos
Adenocarcinoma/cirurgia , Procedimentos Cirúrgicos do Sistema Digestório , Recidiva Local de Neoplasia , Neoplasias Retais/cirurgia , Adenocarcinoma/epidemiologia , Adenocarcinoma/patologia , Adenocarcinoma/radioterapia , Adulto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Estudos de Coortes , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Análise Multivariada , Invasividade Neoplásica , Estadiamento de Neoplasias , Noruega/epidemiologia , Radioterapia Adjuvante , Neoplasias Retais/epidemiologia , Neoplasias Retais/patologia , Neoplasias Retais/radioterapia , Fatores Sexuais , Taxa de Sobrevida , Resultado do Tratamento
18.
Tob Control ; 15(3): 160-5, 2006 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-16728745

RESUMO

OBJECTIVES: To assess the magnitude of cigarette smuggling after the market opened in Taiwan. METHODS: Review of tobacco industry documents for references to smuggling activities related to Taiwan and government statistics on seizure of smuggled cigarettes. RESULTS: The market opening in 1987 led to an increase in smuggling. Contraband cigarettes became as available as legal ones, with only a small fraction (8%) being seized. Being specifically excluded from the market-opening, Japan entered the Taiwan market by setting up a Swiss plant as a legal cover for smuggling 10-20 times its legal quota of exports to Taiwan. Smuggling in Taiwan contributed to increased consumption of foreign brands, particularly by the young. Taiwan, not a member of the World Health Organization, was excluded from the East Asian 16-member "Project Crocodile", a regional anti-smuggling collaborative effort to implement the Framework Convention on Tobacco Control. CONCLUSIONS: Taiwan showed a sharp increase in smuggling after market liberalisation. Being excluded from the international community, Taiwan faces an uphill battle to fight smuggling alone. If Taiwan remained as its weakest link, global efforts to reduce tobacco use will be undermined, particularly for countries in the East Asian region.


Assuntos
Comércio/estatística & dados numéricos , Crime/estatística & dados numéricos , Nicotiana , Adolescente , Adulto , Comportamento do Consumidor/estatística & dados numéricos , Feminino , Humanos , Masculino , Fumar/epidemiologia , Taiwan/epidemiologia , Indústria do Tabaco
19.
J Natl Cancer Inst ; 81(3): 200-4, 1989 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-2911083

RESUMO

The present study examined the prevalence, correlates, and perceived impact of smoking policies among private employers and public agencies in Texas. An identical survey instrument was administered to two groups of Texas employers: a random sample of private industries and all state agencies (excluding universities). Response rates were 62% (n = 420) for private industries and 73% (n = 130) for public agencies. Fifty-two percent of state agencies and 53% of private employers reported having a smoking policy, with the majority of policies having been implemented since 1986. Concern about employees' health or comfort was the most important reason for implementing a policy for both state agencies and private employers. Both groups believed that implementation of a policy resulted in fewer complaints from employees and less smoking in the workplace but had less impact on productivity or morale. This study on the prevalence of smoking policies in the workplace is the first to document that the majority of surveyed employers have a restrictive smoking policy in place. In addition, this study found minimal differences in the prevalence, rationale, and perceived benefits of smoking policies between private employers and state agencies.


Assuntos
Política Pública , Fumar , Humanos , Indústrias , Inquéritos e Questionários , Texas
20.
Waste Manag ; 54: 44-52, 2016 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-27211312

RESUMO

Plastics recycling has the potential to substitute virgin plastics partially as a source of raw materials in plastic product manufacturing. Plastic as a material may contain a variety of chemicals, some potentially hazardous. Phthalates, for instance, are a group of chemicals produced in large volumes and are commonly used as plasticisers in plastics manufacturing. Potential impacts on human health require restricted use in selected applications and a need for the closer monitoring of potential sources of human exposure. Although the presence of phthalates in a variety of plastics has been recognised, the influence of plastic recycling on phthalate content has been hypothesised but not well documented. In the present work we analysed selected phthalates (DMP, DEP, DPP, DiBP, DBP, BBzP, DEHP, DCHP and DnOP) in samples of waste plastics as well as recycled and virgin plastics. DBP, DiBP and DEHP had the highest frequency of detection in the samples analysed, with 360µg/g, 460µg/g and 2700µg/g as the maximum measured concentrations, respectively. Among other, statistical analysis of the analytical results suggested that phthalates were potentially added in the later stages of plastic product manufacturing (labelling, gluing, etc.) and were not removed following recycling of household waste plastics. Furthermore, DEHP was identified as a potential indicator for phthalate contamination of plastics. Close monitoring of plastics intended for phthalates-sensitive applications is recommended if recycled plastics are to be used as raw material in production.


Assuntos
Habitação/estatística & dados numéricos , Indústrias/estatística & dados numéricos , Ácidos Ftálicos/análise , Plásticos/análise , Eliminação de Resíduos/métodos , Política Ambiental , Poluentes Ambientais , Reciclagem/métodos , Eliminação de Resíduos/estatística & dados numéricos
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