RESUMO
In this manuscript, we report three cases of penetrating abdominal injury: one with pellet injury, one with pellet injury after a bomb explosion and one with gunshot injury. All three patients were successfully managed nonoperatively. A 30-year-old male was admitted to our trauma and emergency service with a pellet injury. His physical examination revealed multiple pellet injuries in the left upper abdominal quadrant, left hemithorax, left axilla, dorsal side of the abdomen, left upper extremity, and left gluteus. The second case was a 16-year-old male admitted with a shrapnel injury after a bomb explosion. His physical examination revealed multiple shrapnel injuries in the thoracal and abdominal regions, extremities and left eye. The third case was a 30-year-old male admitted with gunshot and stab wound injury. He had multiple stab wound injuries in both lower extremities and a gunshot wound in the left posterosuperior hemithorax, left upper abdomen and left dorsolumbar region. All these cases were treated non-operatively. We advocate a policy of selective conservatism based on careful initial and subsequent serial clinical examinations and imaging techniques as needed.
Assuntos
Traumatismos Abdominais/cirurgia , Ferimentos por Arma de Fogo/cirurgia , Ferimentos Perfurantes/cirurgia , Traumatismos Abdominais/diagnóstico por imagem , Adolescente , Adulto , Algoritmos , Humanos , Masculino , Traumatismo Múltiplo/cirurgia , Tomografia Computadorizada por Raios X , Ferimentos por Arma de Fogo/diagnóstico por imagemRESUMO
Hand motor representation area expands towards the area of the perioral facial motor cortex in patients with peripheral facial paralysis (PFP) and in hemifacial spasm cases treated with botulinum toxin. In this current study, we aimed to investigate the changes both in the ipsilateral and contralateral facial motor cortex areas in patients with PFP with transcranial magnetic stimulation (TMS). Thirty healthy individuals and 41 patients with unilateral PFP with partial or total axonal degeneration participated in this study. Motor evoked potentials (MEPs) of perioral muscles elicited by TMS of the intracranial portion of the facial nerve and motor cortex, were recorded. TMS was delivered through a figure-of-eight coil. Mapping of the cortical representation of perioral muscles were also studied in 13 of 41 patients and in 10 of control subjects. Mean amplitude of the intact perioral MEPs elicited by the ipsilateral hemisphere TMS, was significantly higher in patients than the control subjects. There was also a mild enlargement of the mean cortical representation area of intact perioral muscles on both hemispheres though it was not significant. We have concluded that there was a cortical reorganization in the hemisphere contralateral to the paralytic side resulting in an increase at corticofugal output related to intact perioral muscles.
Assuntos
Paralisia Facial/fisiopatologia , Córtex Motor/fisiopatologia , Plasticidade Neuronal/fisiologia , Adulto , Idoso , Estudos de Casos e Controles , Eletromiografia , Potencial Evocado Motor/fisiologia , Músculos Faciais/fisiopatologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estimulação Magnética TranscranianaRESUMO
Oropharyngeal dysphagia is not rare in older children before the adult age, especially the patients with cerebral palsy. Non-invasive simple tests are needed for the evaluation of children with neurogenic dysphagia including the patients with cerebral palsy. So we aimed to evaluate non-invasive ways to screen for dysphagia in children and the usefulness of this almost new electrophysiologic method for the detection of dysphagia in children with cerebral palsy. Twenty-eight healthy children and 12 patients with cerebral palsy were investigated for the applicability of this method. The movement of the larynx was monitored using a simple piezoelectric wafer sensor and submental surface EMG activity was recorded by bipolar silver-chloride electrodes taped under the chin over the submental muscle complex. The onset and duration of pharyngeal swallowing was recorded from submental-suprahyoid muscles such as the mylohyoid-genitohyoid-anterior digastric complex. By this method, the maximal water volume capacity was measured in single swallows with progressively increasing water volumes, this was called 'dysphagia limit'. The healthy control children revealed to swallow the bolus at once maximally 11.2+/-0.4 and 2.5 ml in average. Dysphagia limit varied from 7 to above 20 ml water volume from age 5-16 years old. Patients with cerebral palsy had the dysphagia limit of 7.7+/-1.8 and 6.4 ml in average. The dysphagia limit was significantly reduced in patients with cerebral palsy (p<0.05). Dysphagia limit seemed to be less sensitive in demonstrating the oropharyngeal swallowing disorders in childhood period (90% in the adult dysphagic patients). But the majority of patients with cerebral palsy (58%) showed abnormality. This electrophysiologic method is completely non-invasive, devoid from any hazard and applicable to children above 5 years. It may be candidate as a screening test before selection of dysphagic children.
Assuntos
Transtornos de Deglutição/diagnóstico , Transtornos de Deglutição/fisiopatologia , Adolescente , Paralisia Cerebral/epidemiologia , Criança , Pré-Escolar , Queixo , Transtornos de Deglutição/epidemiologia , Eletromiografia , Feminino , Fluoroscopia , Humanos , Masculino , Músculo Esquelético/inervação , Índice de Gravidade de Doença , Gravação de VideoteipeRESUMO
BACKGROUND: The modern management of penetrating abdominal trauma has decreased the incidence of unnecessary laparotomy by using selective non-operative management protocols. However, the real benefits of physical examination and different diagnostic methods are still unclear. METHODS: From January 2000 to April 2003, we prospectively collected data on 117 patients with penetrating stab wounds to the thoracoabdominal, anterior abdominal, and back regions who had non-operative management. Clinical examination was the primary tool to differentiate those patients requiring operation. Findings of physical examination, ultrasound, computed tomography, endoscopy, echocardiography, diagnostic peritoneal lavage, and diagnostic laparoscopy were reviewed. The number of therapeutic, non-therapeutic, and negative laparotomies were recorded. RESULTS: Non-operative management was successful in 79% of patients. There were 11 early (within 8 hours of admission) and 14 delayed (more than 8 hours after admission) laparotomies performed, depending on the results of various diagnostic procedures. Non-operative management failed in 21% of patients, and the rate of non-therapeutic laparotomy in early and delayed laparatomy groups was 9% and 14% respectively. There was no negative laparatomy. CONCLUSIONS: The use of physical examination alone and/or together with different diagnostic methods allows reduction of non-therapeutic laparotomies and elimination of negative laparatomies.
Assuntos
Traumatismos Abdominais/diagnóstico , Laparotomia/estatística & dados numéricos , Exame Físico/métodos , Procedimentos Desnecessários/estatística & dados numéricos , Ferimentos Perfurantes/diagnóstico , Adolescente , Adulto , Colonoscopia/estatística & dados numéricos , Ecocardiografia/estatística & dados numéricos , Feminino , Mau Uso de Serviços de Saúde , Humanos , Laparotomia/métodos , Masculino , Pessoa de Meia-Idade , Lavagem Peritoneal/métodos , Estudos Prospectivos , Tomografia Computadorizada por Raios X/estatística & dados numéricosRESUMO
BACKGROUND AND PURPOSE: We have investigated the pathophysiological mechanisms of dysphagia in Wallenberg's syndrome (WS) that are due to lateral medullary infarction (LMI). METHODS: Twenty patients with WS were evaluated by means of clinical and electrophysiological methods that measured the oropharyngeal phase of voluntarily initiated swallowing. For comparison, 22 patients with unilateral hemispheric infarction were investigated during the acute stage of stroke, and 4 patients with unilateral peripheral 9th and 10th cranial nerve palsies were studied. Age-matched 30 healthy control subjects were also included in the study. RESULTS: It was found that dysphagia was clinically more severe in WS patients than in the patients in the other groups. The pharyngeal phase of swallowing was predominantly impaired, whereas in patients with hemispheric stroke, dysphagia was related only to the delay of triggering of the voluntarily induced swallowing. In WS patients, the swallowing reflex was extremely slow in spite of the unilateral involvement due to LMI, whereas the pharyngeal phase of reflex swallowing remained within normal limits in patients with unilateral hemispheric stroke and patients with unilateral peripheral 9th and 10th cranial nerve palsies. CONCLUSIONS: Although in WS the lesion due to LMI is unilateral, its effect on oropharyngeal swallowing is bilateral. In LMI, primarily the premotor neurons in the nucleus ambiguous and their connections seem to be affected. Consequently, a disruption and/or disconnection of their linkage to swallowing-related cranial motor neuron pools bilaterally and to the contralateral nucleus ambiguous could produce the swallowing disorders in WS. However, the remaining intact ipsilateral premotor neurons and the contralateral center in the medulla oblongata may eventually begin to operate and overcome the severity and long-term persistence of dysphagia.
Assuntos
Transtornos de Deglutição/fisiopatologia , Síndrome Medular Lateral/fisiopatologia , Bulbo/fisiopatologia , Neurônios Motores , Adulto , Idoso , Doenças dos Nervos Cranianos/complicações , Doenças dos Nervos Cranianos/diagnóstico , Doenças dos Nervos Cranianos/fisiopatologia , Deglutição , Transtornos de Deglutição/etiologia , Eletromiografia , Feminino , Humanos , Laringe/fisiopatologia , Síndrome Medular Lateral/complicações , Síndrome Medular Lateral/diagnóstico , Masculino , Bulbo/irrigação sanguínea , Pessoa de Meia-Idade , Recuperação de Função Fisiológica , Reflexo , Acidente Vascular Cerebral/complicações , Acidente Vascular Cerebral/diagnóstico , Acidente Vascular Cerebral/fisiopatologiaRESUMO
Levodopa has been used to treat some painful conditions and found to be effective in neuropathic pain due to herpes zoster in a double-blind study. From our anecdotal observations about the efficacy of levodopa on diabetic neuropathic pain, we designed a double-blind placebo-controlled study to test levodopa in painful diabetic neuropathy. Twenty-five out-patients with painful symmetrical diabetic polyneuropathy were admitted to the study. Fourteen patients were given 100 mg levodopa plus 25 mg benserazide to be taken three times per day for 28 days. Eleven patients were given identical placebo capsules. A blinded neurologist evaluated the patients clinically and performed Visual Analogue Scale (VAS) measurement every week from day 0 to day 28. The results seemed promising and levodopa may be a choice for the control of pain in neuropathy for which we do not have many alternative treatments.
Assuntos
Neuropatias Diabéticas/tratamento farmacológico , Neuropatias Diabéticas/fisiopatologia , Dopaminérgicos/uso terapêutico , Levodopa/uso terapêutico , Cuidados Paliativos , Doenças do Sistema Nervoso Periférico/tratamento farmacológico , Doenças do Sistema Nervoso Periférico/fisiopatologia , Adulto , Idoso , Benserazida/uso terapêutico , Método Duplo-Cego , Combinação de Medicamentos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Medição da DorRESUMO
The effect of the topical anaesthesia of the oropharyngeal mucosae was studied in order to evaluate the role of the mucosal sensory receptors on the oropharyngeal swallowing in 12 adult volunteers. Laryngeal vertical movements were detected by a piezoelectric sensor and electromyography of the submental muscle complex were simultaneously recorded. All subjects were instructed to swallow doses of water, gradually increasing in quantity from 3-20 mL and any recurrence of the signals related to swallowing within 8 s was accepted as a sign of dysphagia and its limit value measured. Before the topical anaesthesia of the oropharyngeal mucosae by xylocaine puffs; the dysphagia limit was never observed with less than 20 mL water. During topical mucosal anaesthesia lasting 4-6 min among the subjects, the dysphagia limit was less than 20 mL water and the recurrence of swallows two or more times was mainly recorded with 3-5 mL water. Five of the subjects demonstrated the clinical and electrophysiological signs of laryngeal aspiration at the earlier period of the topical anaesthesia. It is concluded that the sensory inputs from the mucosal receptors are important to trigger voluntary swallowing and their absence or dysfunction may contribute to oropharyngeal dysphagia and laryngeal aspiration.
Assuntos
Deglutição/efeitos dos fármacos , Lidocaína/farmacologia , Mucosa Bucal/efeitos dos fármacos , Adulto , Anestésicos Locais/farmacologia , Deglutição/fisiologia , Transtornos de Deglutição/induzido quimicamente , Transtornos de Deglutição/fisiopatologia , Eletromiografia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Orofaringe/fisiologiaRESUMO
In 22 normal human subjects, descending lumbosacral cord potentials (DLCP) were recorded intrathecally after stimulation of the median nerve at the elbow. The onset of DLCP is very short in latency (mean 12.1 ms) with a prominent sharp early positive peak (mean latency 13.7 ms) followed by a sharp negative peak (mean 17.6 ms). The amplitude of the first part of DLCP varied between 0.6 and 6.7 microV (mean 2.3 microV). The response was recorded most easily when the tip of intrathecal electrode was posterolaterally positioned. The threshold of the response was above or around the excitation threshold of the motor nerve fibers and it could not be produced by pure skin nerve stimulation. It resisted to subtetanic peripheral shocks. Mean peripheral conduction velocity responsible for the response was about 60.8 m/s. Some late and slower deflections appeared in many cases. It was concluded that the DLCP must have originated from the descending and very fast conducting propriospinal pathways located within the anterolateral funiculus which has an oligosynaptic anatomical organization. This response seemed to be the first direct evidence of interlimb reflex action between the arm and leg in man which is important in the coordination of movements and posture.
Assuntos
Nervo Mediano/fisiologia , Reflexo/fisiologia , Medula Espinal/fisiologia , Braço/inervação , Potenciais Evocados , Humanos , Perna (Membro)/inervação , Condução Nervosa , Tempo de Reação/fisiologiaRESUMO
OBJECTIVE: To determine the changes in the motor cortex due to repetitive electrical stimulation and cutaneous anesthesia in lower facial region. METHODS: A total of 11 subjects participated in the study of repetitive electrical stimulation, and 10 other subjects in the study of lower facial anesthesia. Facial nerve root and face associated cortical MEPs by transcranial magnetic stimulation (eight-shaped coil) were recorded from perioral muscles pre- and post- electrical stimulation and lower facial anesthesia. Cheek near to the corner of the mouth was transcutaneously stimulated by bipolar surface electrode giving repetitive electrical shocks at 5 Hz. Five percent lidocain/prilocain local anesthetic cream was applied to left or right lip-cheek region. RESULTS: There was no significant change in perioral MEP responses after 10-30 min of 5 Hz electrical stimulation. We found a significant increase of amplitude in cortical MEP recordings during lower facial anesthesia especially in cases of cortical magnetic stimulations ipsilateral and contralateral to the anaesthetized side and in perioral recordings contralateral to the anaesthetized side. CONCLUSIONS: The present study demonstrates that topical anesthesia to the lower facial region leads to cortical modulation and fast plastic changes in both hemispheres that are directed to the normal side.
Assuntos
Córtex Cerebral/fisiologia , Músculos da Mastigação/fisiologia , Adulto , Anestesia , Estimulação Elétrica , Campos Eletromagnéticos , Eletromiografia , Eletrochoque , Nervo Facial/fisiologia , Feminino , Lateralidade Funcional/fisiologia , Humanos , Masculino , Pessoa de Meia-Idade , Plasticidade Neuronal/efeitos dos fármacos , Plasticidade Neuronal/fisiologiaRESUMO
OBJECTIVE: Cricopharyngeal (CP) muscle of the upper oesophageal sphincter (UES) has a significant role in the pharyngo-esophageal phase of deglutition. The linkage between the CP muscle of UES and the motor cortex has not been previously studied electrophysiologically in healthy humans and in patients with neurogenic dysphagia. METHODS: Needle recordings of EMG responses were carried out from the CP sphincter muscle following transcranial magnetic stimulation (TMS) over the vertex around the Cz electrode position (cortical MEP), and on the parieto-occipital skull and the occiput ipsilaterally (peripheral MEP) in 14 healthy control subjects and in 26 patients with and without neurogenic dysphagia. Needle recordings obtained from the cricothyroid muscle of the larynx were also evaluated in six healthy subjects. RESULTS: The cortical motor latency of CP sphincter muscle was 10.7+/-0.5 ms with an amplitude of 0.8+/-0.2 mV in healthy subjects. Both the latency and amplitude of CP-MEP were facilitated during swallowing. The peripheral MEP of the CP muscle was very stable in all normal subjects (5.1+/-0.3 ms; 1.3+/-0.3 mV) and swallowing did not influence these parameters. The cortically elicited CP-MEP was significantly longer than the cortical MEPs obtained from the cricothyroid muscle of the larynx. In 10 dysphagic patients with corticobulbar tract involvement (6 ALS and 4 pseudobulbar palsy) and with pathologic and hyperreflexic EMG of the CP-sphincter muscle, the cortical MEP of CP muscle of the upper esophageal sphincter could not be elicited, although the peripheral CP-MEPs were obtained. TMS never produced a swallowing movement in neither healthy subjects nor patients. CONCLUSION: The CP muscle of the upper esophageal sphincter can produce MEPs by cortical TMS and by stimulation at the root/nerve levels of vagus nerve. The MEP latency values and central motor delay suggest that there is an oligosynaptic corticobulbar pathway to the motoneurons of CP muscles. When the pathway is affected by a pathology (i.e. ALS or pseudobulbar palsy) the CP sphincter becomes hyperreflexic due to disinhibition and the cortical MEP of the CP muscle disappears due to degeneration of the corticobulbar pathway. These mechanisms appear to be responsible for the pathogenesis of dysphagia.
Assuntos
Encéfalo/fisiologia , Transtornos de Deglutição/fisiopatologia , Campos Eletromagnéticos , Músculos Faríngeos/fisiologia , Adolescente , Adulto , Idoso , Encéfalo/fisiopatologia , Eletromiografia , Feminino , Humanos , Laringe/fisiologia , Masculino , Pessoa de Meia-Idade , Córtex Motor/fisiologia , Nervos Periféricos/fisiologia , Músculos Faríngeos/fisiopatologiaRESUMO
The head stabilization reflex (HSR) was described by a new technique of stimulating the accessory nerve and then the reflex muscle responses' were recorded electromyographically from the contralateral sternocleidomastoid muscle. Thirty-two normal control subjects and 22 patients with various neurological disorders were studied. The HSR obtained from the contralateral sternocleidomastoid muscle was very stable with a mean latency of about 45 ms and was regularly obtained by the supramaximal stimulation of the ipsilateral accessory nerve from the normal subjects. The HSR was absent in 9 out 11 patients with cerebellar syndrome. The HSR seemed to be a oligo-polysynaptic/plurosegmental reflex under the strong control of the cerebellum.
Assuntos
Nervo Acessório/fisiologia , Movimentos da Cabeça/fisiologia , Músculos do Pescoço/fisiologia , Doenças do Sistema Nervoso/fisiopatologia , Reflexo/fisiologia , Adolescente , Adulto , Idoso , Estimulação Elétrica , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Doenças do Sistema Nervoso/diagnósticoRESUMO
The bulbocavernosus reflex was investigated electrophysiologically in 14 normal adult male subjects and in 80 patients with neurogenic bladders and/or impotence due to various neurological causes as well as in patients with functional impotence. The glans penis was stimulated superficially by single electrical shocks and the reflex responses were recorded from the bulbocavernosus (BC) and the striated anal sphincter muscles by means of concentric needle EMG electrodes. In all normal subjects, the BC reflex was recorded from the BC muscle as a stable and constant response having a mean latency of 36.1 msec. A response from the external anal sphincter was obtained in only 21% of the subjects investigated. In 13 patients with cauda equina lesions, the BC reflex was either absent or was present with a prolonged latency. Twenty-two patients with polyneuropathy of various causes were also investigated; in these patients the latency of the BC reflex was significantly greater than in the normal controls, but the most abnormal results were obtained in cases of alcoholic polyneuropathy. In the 19 cases of spinal cord disease with spasticity the BC reflex response was very intense, often with after discharges but latency values were within normal limits. In the 16 cases with functional impotence, the BC reflexes were basically normal; but in 3 cases, the threshold of the reflex was significantly raised, and in 1 case a prolonged latency was observed. The value and the practical application of the BC reflex in the BC reflex in the differential diagnosis of bladder dysfunction and of impotence was stressed.
Assuntos
Disfunção Erétil/fisiopatologia , Pênis/fisiopatologia , Reflexo Anormal , Bexiga Urinaria Neurogênica/fisiopatologia , Adolescente , Adulto , Canal Anal/fisiopatologia , Cauda Equina , Disfunção Erétil/etiologia , Humanos , Masculino , Pessoa de Meia-Idade , Doenças do Sistema Nervoso Periférico/complicações , Doenças do Sistema Nervoso Periférico/fisiopatologia , Tempo de Reação , Doenças da Medula Espinal/complicações , Doenças da Medula Espinal/fisiopatologia , Bexiga Urinaria Neurogênica/etiologiaRESUMO
Trigemino-cervical reflexes, recorded from the semispinalis capitis muscle (SCM) in the posterior neck, were studied in 35 healthy volunteers, in response to electrical stimulation of the supraorbital trigeminal nerve and glabellar tapping. Simultaneous responses evoked from the ipsilateral orbicularis oculi muscle (OOM) were also recorded i.e. blink reflexes. Electrical stimulation of the supraorbital nerve elicited a reflex response with a latency of about 50 ms from the ipsilateral SCM which was called C3. An early reflex response, which sometimes had two components with latencies of 18 ms and 35 ms, was elicited with glabellar taps. They were called C1 and C2 respectively. When C1 and C2 were elicited with usual glabellar taps, C3 was suppressed. With electrical stimulation, suppression of C1 and C2 was noted, though C3 could easily be obtained. Electrophysiological characteristics of C1 (and C2) were compatible with an oligosynaptic, innocuous reflex, whereas C3 seemed to be multisynaptic and nociceptive in nature. A negative interaction between these two reflexes was observed.
Assuntos
Piscadela/fisiologia , Nervo Trigêmeo/fisiologia , Adulto , Tronco Encefálico/citologia , Tronco Encefálico/fisiologia , Eletromiografia , Potenciais Somatossensoriais Evocados/fisiologia , Movimentos Oculares/fisiologia , Músculos Faciais/inervação , Músculos Faciais/fisiologia , Feminino , Mãos/inervação , Humanos , Masculino , Pessoa de Meia-Idade , Músculos do Pescoço/inervação , Músculos do Pescoço/fisiologia , Neurônios Aferentes/fisiologia , Reflexo/fisiologiaRESUMO
The clinical value and practical application of the electrically induced BC reflex was investigated in 40 patients with traumatic or compressive lesions of the conus medullaris or cauda equina. It was shown that the BC reflex was either absent or delayed depending upon the invovlement of the sacral 2--4 spinal and radicular segments. The latency of the BC reflex was normal in patients with mainly epiconus and lumbar cord involvement. The loss of the BC reflex in the acute period of traumatic lesions was an adverse prognostic sign while the presence of the reflex whether or not delayed, indicated a more benign final outcome of sphincter and sexual reflex disturbances. In chronic progressive compression, the latency of BC reflex was often delayed.
Assuntos
Cauda Equina , Reflexo Anormal , Doenças da Medula Espinal/diagnóstico , Eletromiografia , Cisto Epidérmico/complicações , Fraturas Ósseas/complicações , Humanos , Deslocamento do Disco Intervertebral/complicações , Luxações Articulares/complicações , Masculino , Tempo de Reação , Doenças da Medula Espinal/etiologia , Neoplasias da Medula Espinal/complicações , Traumatismos da Coluna Vertebral/complicações , SíndromeRESUMO
The clinical value and practical application of the lumbosacral evoked electrospinogram (Espg) and somatosensory cerebral evoked potentials (SEP) were investigated in 52 patients with conus medullaris or cauda equina lesions. It was shown that the destruction or compression of the conus/cauda equina region by traumatic fracture and dislocation of upper lumbar vertebrae, by midline herniation of the nucleus pulposus and by tumoral mass, produced significant reduction in amplitude and delay in latency of Espg recorded just above the lesion site, and the SEP behaved in a similar way. The degree of abnormality was found to be in accord with the severity of clinical sensorimotor deficits in the legs. Tumoural compression caused more significant delay in evoked responses than traumatic injury. From the diagnostic point of view, Espg and SEP were useful in showing latent and manifest involvement of the lumbosacral sensory roots and these are discussed in relation to other electrodiagnostic tests.
Assuntos
Cauda Equina/fisiopatologia , Traumatismos da Medula Espinal/fisiopatologia , Raízes Nervosas Espinhais/fisiopatologia , Nervos Espinhais/fisiopatologia , Adolescente , Adulto , Vias Aferentes/fisiopatologia , Idoso , Cauda Equina/lesões , Potenciais Evocados , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Córtex Somatossensorial/fisiopatologia , Compressão da Medula Espinal/fisiopatologia , Neoplasias da Medula Espinal/fisiopatologia , Raízes Nervosas Espinhais/lesõesRESUMO
In the current study, the effects of stimulation of the infraorbital nerve (ION) on the trigeminocervical reflexes (TCRs), recorded from the posterior neck muscles, was investigated and the results were compared with the results recorded by stimulation of the supraorbital nerve (SON). TCRs obtained by stimulation of the ION was evaluated as the electrophysiologic counterpart of the head retraction reflex. Twenty normal control subjects, 10 men and 10 women, were enrolled in the study. The SON and the ION were stimulated by using a bipolar surface electrode. Results were recorded by using either concentric needle electrodes inserted into the semispinalis capitis muscle at the level of the third or fourth cervical vertebra or by surface electrodes placed at the C3 and C7 vertebrae on the midline. It was found that stimulation of the supraorbital and infraorbital branches of the trigeminal nerve had different reflexive effects on the posterior neck muscles. A stable positive (or negative-positive) wave, with a very early latency and high amplitude was always recorded after maximal stimulation of the ION, which could never be detected by stimulation of the SON. The C3 response of the TCR, evoked by SON stimulation was always evoked, by stimulation of the ION, at a low threshold. These findings suggest that the head retraction reflex is composed of two phases: inhibitory and excitatory. The early, fixed positive wave represents the general inhibition of the cranial and neck muscles, just before withdrawal of the face and head, from unexpected stimuli, which precedes the dense C3 response, demonstrating activation of the posterior neck muscles.
Assuntos
Cabeça/fisiologia , Músculos do Pescoço/fisiologia , Órbita/inervação , Reflexo/fisiologia , Nervo Trigêmeo/fisiologia , Adulto , Estimulação Elétrica , Eletromiografia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Fenômenos Fisiológicos do Sistema NervosoRESUMO
The sacral cord conduction time of the soleus H-reflex was investigated in 30 normal adult subjects using three different methods. (1) The posterior tibial nerve was stimulated at the popliteal fossa by graded electric shocks, and the recordings were made from different lumbar epidural intervertebral levels. The afferent action potentials from the dorsal roots and the reflexively evoked efferent action potentials from the ventral roots were recorded. The time interval between the negative peaks of the ventral and dorsal root potentials was used to calculate the approximate sacral cord reflex delay time, which was found to be 1.3 ms. on average. (2) The sacral cord reflex delay time was found to be about 2.0 ms using the conduction time of the afferent, that of the efferent limbs and total reflex time of the soleus H-response. (3) By stimulating the lumbosacral roots at the epidural levels and using the difference between the soleus H and M response latencies, the sacral cord reflex delay was determined to be approximately 2.4 ms. These findings indicated that the soleus H-reflex is exclusively monosynaptic. It is proposed that in humans the synaptic transmission at the sacral cord is approximately 0.4 ms.
Assuntos
Reflexo H/fisiologia , Músculo Esquelético/inervação , Medula Espinal/fisiologia , Adulto , Vias Aferentes/fisiologia , Estimulação Elétrica , Eletromiografia , Feminino , Gânglios Espinais/fisiologia , Humanos , Masculino , Pessoa de Meia-Idade , Tempo de Reação/fisiologia , Valores de Referência , Reflexo Monosináptico/fisiologia , Nervo Tibial/fisiologiaRESUMO
BACKGROUND: Only a few patients with active nonesophageal variceal upper gastrointestinal bleeding have been treated with endoscopic ligation. To further address this issue, four patients with active bleeding Mallory-Weiss tears who underwent endoscopic band ligation are presented. PATIENTS AND METHODS: Endoscopic ligation was performed in four patients with a median age of 52 years (range, 40-93 years) after a diagnosis of active bleeding Mallory-Weiss tears (MWTs). A 45-year-old man with massive persistent upper gastrointestinal bleeding as a cause of a MWT underwent therapeutical endoscopic band ligation after an unsuccessful endoscopic injection trial. On the contrary, injection therapy should have been performed on a 93-year-old woman with multiple myeloma because of an actively bleeding MWT caused by the fibrotic tissue after an unsuccessful endoscopic ligation trial, although her other actively bleeding MWT lesion had been ligated successfully. RESULTS: After endoscopic ligation, all patients achieved complete hemostasis, and rebleeding did not occur. They were discharged without complications after a control endoscopy. CONCLUSIONS: Endoscopic ligation can be performed easily and without any complications such as perforation or delayed hemorrhage in patients with actively bleeding nonfibrotic MWTs.
Assuntos
Endoscopia/métodos , Síndrome de Mallory-Weiss/cirurgia , Adulto , Idoso , Idoso de 80 Anos ou mais , Humanos , Ligadura/métodos , Masculino , Pessoa de Meia-IdadeRESUMO
Dieulafoy's lesion is a rare arterial malformation that can cause massive gastrointestinal hemorrhage. The lesion occurs most commonly in the proximal stomach. The esophagus is not a common location for this lesion. We present the case of a 25-year-old woman who was admitted to our emergency unit with the findings of hematemesis and melena. Early upper gastrointestinal endoscopic examination revealed a Dieulafoy's lesion, which was located in the distal esophagus. Endoscopic band ligation stopped the bleeding successfully. The patient was discharged 3 days after the band ligation without any complications. Dieulafoy's lesion may cause severe, life-threatening bleeding. Endoscopic diagnosis can be difficult because of the small size and obscure location of the lesion. An abnormally dilated artery that penetrates through the mucosa constitutes the etiology. Endoscopy plays an important role in the diagnosis and treatment of this pathology. Despite widespread awareness of this entity, it may present a real challenge for the endoscopist due to the small size and hidden location of the lesion. The endoscopic approach to occult gastrointestinal bleeding for the diagnosis of vascular malformations is accepted as a quick and safe diagnostic method.
Assuntos
Doenças do Esôfago/cirurgia , Esôfago/irrigação sanguínea , Hemorragia Gastrointestinal/cirurgia , Adulto , Artérias/anormalidades , Junção Esofagogástrica/irrigação sanguínea , Junção Esofagogástrica/cirurgia , Esôfago/cirurgia , Feminino , Hematemese/etiologia , Hematemese/cirurgia , Hemostase Endoscópica/métodos , Humanos , Melena/etiologia , Melena/cirurgia , Trombose/cirurgiaRESUMO
STUDY DESIGN: This prospective study includes normal control subjects and patients with focal lesions of the spinal cord investigated by transcranial magnetic stimulation. OBJECTIVES: To establish a stable method to elicit motor evoked potentials from cervical to lumbar segmental levels and to apply the method that would allow the localization in patients with restricted cord lesion. Thirty-four healthy subjects (10 women, 24 men) and 17 patients with focal spinal lesions were admitted to this study. SUMMARY OF BACKGROUND DATA: The focal cord lesions and injuries were previously evaluated by the records of lower limb muscles after cortical stimulation, but this method did not demonstrate the vertebral levels at which the lesions were located. METHODS: The paravertebral myotomal-evoked potentials were recorded in different segmental levels (T1, T6, T12, and L3) from paravertebral muscles, using surface and needle electrodes by transcranial magnetic stimulation in normal control subjects and patients. RESULTS: In normal control subjects, paravertebral myotomal-evoked potentials were obtained from T1, T6, T12, and L3 paravertebral muscles with both recording techniques (surface and needle electrode). From T1 to L3 latencies of paravertebral myotomal-evoked potentials increased gradually (from 10 msec to 17 msec) in normal control subjects. The levels of spinal cord lesions were obtained reliably in 14 of 17 patients with thoracic-lumbar spinal cord lesions, by using both electrophysiologic methods. In 11 of 14 patients, the lesions produced total conduction block, at and below the lesion level. In the remaining 3 patients slowing of intersegmental conduction was observed along the focal cord lesion. CONCLUSIONS: The paravertebral myotomal-evoked potentials obtained by surface electrode from paravertebral muscles and by midline needle electrode in the intrinsic rotatory muscles of the spine were useful in localizing lesions in the spinal segments in most of the patients with thoracic-lumbar cord lesions.