RESUMO
We studied two cases of bilateral choroidal osteoma in an otherwise healthy 5-year-old boy and his only sibling, a 7-year-old sister. Both children were known to have normal fundus appearances at younger ages. The tumor showed slow growth in all four eyes, but severe visual acuity loss developed in three eyes because of neovascular complications that could not be effectively treated by photocoagulation. Secondary retinal cysts developed in three eyes.
Assuntos
Neoplasias da Coroide/genética , Osteoma/genética , Criança , Pré-Escolar , Neoplasias da Coroide/patologia , Cistos/etiologia , Cistos/cirurgia , Feminino , Fundo de Olho , Humanos , Fotocoagulação , Masculino , Osteoma/patologia , Neovascularização Retiniana/etiologia , Neovascularização Retiniana/cirurgia , Acuidade VisualRESUMO
PURPOSE: To demonstrate that hairy cell leukemia may involve the eye. METHODS: We examined a patient who had a unique ocular manifestation of hairy cell leukemia with severe panuveitis in one eye and leukemic retinopathy in the fellow eye. RESULTS: Therapy with 2-chloro-deoxy-adenosine, a drug recently introduced for treatment of hairy cell leukemia, led to dramatic improvement of the ocular complications. CONCLUSIONS: Hairy cell leukemia may involve the eye and ocular symptoms may respond to systemic treatment with 2-chloro-deoxy-adenosine.