1.
Org Lett
; 22(20): 8167-8172, 2020 Oct 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32991191
RESUMO
Trifluorovinylzinc is a common synthetic intermediate for trifluorovinyl derivatives, including α,ß,ß-trifluorostyrenes and hexafluorobutadiene. Here, we report a novel synthetic approach for the formation of trifluorovinylzinc chloride via a C-F bond activation of tetrafluoroethylene (TFE), which is an industrially cost-effective bulk feedstock with a negligible GWP. The present system provides a practical synthetic route to various trifluorovinyl derivatives with very low energy consumption.