Detalhe da pesquisa
1.
The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition.
J Am Chem Soc
; 145(2): 851-863, 2023 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36603206
2.
Chemical Validation of Mycobacterium tuberculosis Phosphopantetheine Adenylyltransferase Using Fragment Linking and CRISPR Interference.
Angew Chem Int Ed Engl
; 62(17): e202300221, 2023 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36757665
3.
Cellular and Molecular Mechanisms in Mycobacterial Infection.
Int J Mol Sci
; 23(13)2022 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35806210
4.
Blocking Bacterial Naphthohydroquinone Oxidation and ADP-Ribosylation Improves Activity of Rifamycins against Mycobacterium abscessus.
Antimicrob Agents Chemother
; 65(9): e0097821, 2021 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34228543
5.
In Vitro Efficacies, ADME, and Pharmacokinetic Properties of Phenoxazine Derivatives Active against Mycobacterium tuberculosis.
Antimicrob Agents Chemother
; 63(11)2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31427302
6.
The Influence of HIV on the Evolution of Mycobacterium tuberculosis.
Mol Biol Evol
; 34(7): 1654-1668, 2017 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28369607
7.
Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria.
Mol Microbiol
; 103(1): 13-25, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27677649
8.
Expanding the knowledge around antitubercular 5-(2-aminothiazol-4-yl)isoxazole-3-carboxamides: Hit-to-lead optimization and release of a novel antitubercular chemotype via scaffold derivatization.
Eur J Med Chem
; 245(Pt 2): 114916, 2023 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36399878
9.
Chemical Validation of Mycobacterium tuberculosis Phosphopantetheine Adenylyltransferase Using Fragment Linking and CRISPR Interference.
Angew Chem Weinheim Bergstr Ger
; 135(17): e202300221, 2023 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38515507
10.
Targeting Mycobacterium tuberculosis CoaBC through Chemical Inhibition of 4'-Phosphopantothenoyl-l-cysteine Synthetase (CoaB) Activity.
ACS Infect Dis
; 7(6): 1666-1679, 2021 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33939919
11.
Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site.
Nat Commun
; 12(1): 143, 2021 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33420031
12.
Priming the tuberculosis drug pipeline: new antimycobacterial targets and agents.
Curr Opin Microbiol
; 45: 39-46, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29482115
13.
Validation of CoaBC as a Bactericidal Target in the Coenzyme A Pathway of Mycobacterium tuberculosis.
ACS Infect Dis
; 2(12): 958-968, 2016 12 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27676316
14.
The application of tetracyclineregulated gene expression systems in the validation of novel drug targets in Mycobacterium tuberculosis.
Front Microbiol
; 6: 812, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26300875
15.
The complex mechanism of antimycobacterial action of 5-fluorouracil.
Chem Biol
; 22(1): 63-75, 2015 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25544046
16.
Nucleotide Metabolism and DNA Replication.
Microbiol Spectr
; 2(5)2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26104350
17.
A novel insertion sequence, ISPA26, in oprD of Pseudomonas aeruginosa is associated with carbapenem resistance.
Antimicrob Agents Chemother
; 51(10): 3776-7, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17682099