RESUMO
The aim of the article was to study morphological features of esophageal mucosa in patients with type II diabetes mellitus and gastroesophageal reflux disease (GERD). The research was conducted on 67 patients with type II diabetes mellitus and GERD and 50 non-diabetic patients with GERD. The histological study of the mucous membrane of the distal esophagus in patients with combined pathology detected parakeratosis and acanthosis, outflows edema and bundles epithelium, surfacial hyperplasia, infiltration of neutrophils and vascular ectasia. The obtained results demonstrate that type II diabetes causes change in symptoms, endoscopic and histologic manifestations of GERD. It is concluded about the importance to develop and improve diagnostic tools for the detection of GERD with type II diabetes by means of invasive and non-invasive diagnostic techniques.
Assuntos
Diabetes Mellitus Tipo 2/patologia , Esôfago/patologia , Refluxo Gastroesofágico/patologia , Mucosa/patologia , Diabetes Mellitus Tipo 2/complicações , Endoscopia , Feminino , Refluxo Gastroesofágico/complicações , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
These patients require individual rehabilitation after determination of the unspecific reactivity of the body with prodigiosane. Depending on the results of this test the patients were treated with drugs stimulating the immune response in case of hyporeactivity, with adaptogens in normoreactive course of the disease and drugs modulating B-cell immunity in hyperreactivity. This approach allows to reduce hospital time, enhances remission.
Assuntos
Acidentes de Trabalho , Contaminação Radioativa do Ar/efeitos adversos , Úlcera Duodenal/reabilitação , Reatores Nucleares , Exposição Ocupacional/efeitos adversos , Centrais Elétricas , Adulto , Terapia Combinada , Úlcera Duodenal/imunologia , Humanos , Imunidade Inata/efeitos da radiação , Masculino , Indução de Remissão , Fatores de Tempo , UcrâniaRESUMO
A study is presented of 107 patients with chronic hepatitis and liver cirrhosis verified on the basis of morphological changes of the punctate obtained at echocontrol puncture liver biopsy. It was established that clinical manifestations of chronic hepatitis and liver cirrhosis are determined not only by their morphological forms, but also by the structure of the inflammatory infiltrate of the liver tissue. This is to be considered in evaluation of the severity of the disease course and differentiated treatment.