[Hemorheological changes in hot and humid environment].

OBJECTIVE: To observe the changes in hemorheology of human under hot and humid environment. METHODS: Ninety soldiers serving in the Nansha Islands were divided into veteran group, recruit group and urapidil-treated recruit group, all of whom were required to complete 3 000-meter running exercise in 20 min in hot and humid environment. Their hemorheology were examined before and after the exercise. RESULTS: There were significant difference in the hemorheology between the 3 groups (P<0.05) both before and after the exercise, and the changes were most obvious in the veteran group followed by the new recruit group and urapidil-treated recruit group. No significant differences in the plasma indexes were detected between the 3 groups. CONCLUSIONS: Hot and humid environment causes obvious changes in the hemorheology, for which veterans and recruits have different tolerances and adaptabilities. Uradipil may help lower the magnitude of the the hemorheological changes after exercise by reducing body metabolism.

[Study of the association of Malassezia furfur with chronic urticaria among the ship crews].

OBJECTIVE: To investigate the association of Malassezia furfur with chronic urticaria in the crew members of ships. METHODS: A comparative mycological study of 126 crew members of ships with chronic urticaria and 45 normal control subjects was carried out. The 82 urticaria patients identified as positive for Malassezia furfur were divided into groups A and B to receive treatment with antihistaminics (group A) and antihistaminics combined with 2% ketoconazole shampoo(group A). RESULTS: The carrier rates of Malassezia furfur were significantly higher in urticaria patients than in the normal control subjects (P<0.01), but in view of the case ratios of the final cure or improvement, no significant difference was observed between the two groups by the end of the treatment courses (P>0.05). But 6 to 8 weeks from the end of the treatment course, better therapeutic effect was noted in group B (P<0.01), with higher rate of negative Malassezia furfur findings (P<0.01). CONCLUSION: Malassezia furfur may play an important role in the prevalence of chronic urticaria among the crew members, and anti-fungal treatment may produce better long-term therapeutic effect.

[Analysis of the diagnosis and treatment of recurrent vulvovaginal candidiasis in 80 cases].

OBJECTIVE: To investigate the appropriate therapy for treating recurrent vulvovaginal candidiasis (RVVC). METHODS: Individual consolidated and maintenance therapy were chosen according to fungal culture of vaginal secretion and antifungal drug sensitivity per month as one therapy duration. Drugs were used orally and vaginally together to consolidate the therapy. Oral drugs were fluconazole (0.15 qw after 0.15 q3d for 2 times) or ketoconazole (0.2, bid for 3 days ) or itraconazole (0.2 bid for 3 days ). After Nystain (400 000 unit qn for 7 days ) or clotrimazole(0.1 qn for 7 days) or amphotericin B (0.01 qn for 6 days ) being vaginally used, Living preparation of lactobacillus (0.25 qn for 5 days) was vaginally used. The therapy was continued for 2 to 5 therapy durations after the symptoms disappeared with negative fungal culture. RESULTS: Among 80 cases of RVVC, C. albicans was mostly detected (74%), C. glabrata was 20%. The susceptivity to candidas of oral agents revealed that the sensitive rare of ketoconazole, fluconazole and itraconazole were (91.3%), (81.3%) and (62.5%), respectively. As for vaginal agents, nystain and amphotericin B were 100% sensitive, clotrimazole was 92.5%sensitive, miconazole was 55.0% sensitive. The remote cure of 3 and 6 therapy durations after discontinuing for 12 months was 78.9% and 90.4% CONCLUSION: The predominant pathogen in RVVC is C. albicans. The effective measures to cure RVVC are to choose sensitive drugs for individual consolidated, maintenance therapy and restore vaginal acidic environment.