Staging and Restaging Pediatric Abdominal and Pelvic Tumors: A Practical Guide.

The most common abdominal malignancies diagnosed in the pediatric population include neuroblastoma, Wilms tumor, hepatoblastoma, lymphoma, germ cell tumor, and rhabdomyosarcoma. There are distinctive imaging findings and patterns of spread for each of these tumors that radiologists must know for diagnosis and staging and for monitoring the patient's response to treatment. The multidisciplinary treatment group that includes oncologists, surgeons, and radiation oncologists relies heavily on imaging evaluation to identify the best treatment course and prognostication of imaging findings, such as the image-defined risk factors for neuroblastomas, the PRETreatment EXtent of Disease staging system for hepatoblastoma, and the Ann Arbor staging system for lymphomas. It is imperative for radiologists to be able to correctly indicate the best imaging methods for diagnosis, staging, and restaging of each of these most prevalent tumors to avoid inconclusive or unnecessary examinations. The authors review in a practical manner the most updated key points in diagnosing and staging disease and assessing response to treatment of the most common pediatric abdominal tumors. ©RSNA, 2024 Supplemental material is available for this article.

Prevalence and Factors Associated with Olfactory Dysfunction in Individuals with COVID-19 in Brazil: A Study of 20,669 Cases from 2020 to 2021.

OBJECTIVE: The aim of the study is to determine the prevalence and factors associated with olfactory dysfunction in individuals with COVID-19 in the first 2 years of the pandemic in Brazil. MATERIALS AND METHODS: This is a prevalent study involving the confirmed cases of COVID-19 recorded in the municipality between the years 2020 and 2021. Individuals symptomatic for COVID-19, with a positive laboratory result and aged 12 or older were included in this study. Measures of central tendency and dispersion were used in the description of continuous variables and frequency was used for categorical variables. The Shapiro-Wilk test was used to evaluate data distribution. RESULTS: Data from 20,669 individuals were analyzed. The prevalence of olfactory disorders was 17.9% and increased from 11.5% to 21.9% between 2020 and 2021. A female gender predominance was observed among individuals who reported anosmia, with 61.1% (n = 564) in 2020 and 61.7% (n = 1,713) in 2021. On the other hand, the median age of individuals with olfactory disorders was lower than that of the group without disorders (35 [IQR 27-46] vs. 39 [IQR 29-50]; p < 0.001). Smell disturbances were present in 18.2% (n = 3,634) of patients who recovered and in 7.1% (n = 38) of those who died. Furthermore, in 2021, a prevalence rate of 30.6% for olfactory disorders was linked to obesity as a comorbidity. CONCLUSION: The prevalence of olfactory disorders was lower compared to other studies, with cough and fever being negatively related to olfactory dysfunction and headache, coryza, and taste disorders being positively related. Obesity was the only associated comorbidity.

Liver Surgery: Important Considerations for Pre- and Postoperative Imaging.

Liver surgery may be a curative treatment option not only for primary liver neoplasms but also for liver metastases in selected patients. The number of liver surgeries performed worldwide has increased, but surgical morbidity associated with these surgeries remains significant. Therefore, radiologists need to understand the terminology, surgical techniques, resectability and unresectability criteria, and possible postoperative complications as these are part of the decision-making process. Because vascular and biliary variations are common, an adequate preoperative anatomic evaluation determines the best surgical technique, helps identify patients in whom additional surgical steps will be required, and reduces the risk of inadvertent injury. The surgeon must ensure that the future liver remnant is sufficient to maintain adequate function, aided by the radiologist who can provide valuable information such as the presence of steatosis, biliary dilatation, signs of cirrhosis, and portal hypertension, in addition to the volume of the future liver remnant. Postoperative complications must also be understood and evaluated. The most common postoperative complications are vascular (bleeding, thrombosis, and ischemia), biliary (fistulas, bilomas, and strictures), infectious (incisional or deep), those related to liver failure, and even tumor recurrence. An invited commentary by Winslow is available online. Online supplemental material is available for this article. ©RSNA, 2022.

Measuring parental and family efficacy beliefs of adolescents' parents: Cross-cultural comparisons in Italy and Portugal.

The goal of this study was to examine the psychometric properties of the Perceived Parental Self-Efficacy (PPSE) and Perceived Family Collective Efficacy (PFCE) revised scales in the Portuguese and Italian contexts. To this aim two studies were conducted: the first reported the exploratory and confirmatory factor analyses with Portuguese samples, whereas the second addressed the cross-cultural invariance of PPSE and PFCE (Portugal and Italy). Results of the first study showed the appropriate fit of the unifactorial model of both scales to Portuguese data. The invariance analyses performed in the second study attested to the PPSE and PFCE's configural, metric and scalar invariance in both countries. The correlations of PPSE and PFCE with communication, management of conflict and children's school achievement further attested to their construct and practical validity. Thus, PPSE and PFCE proved to be suitable to further use in research and psychological assessment fields.

The artificial sweetener neotame negatively regulates the intestinal epithelium directly through T1R3-signaling and indirectly through pathogenic changes to model gut bacteria.

Introduction: Recent studies have indicated considerable health risks associated with the consumption of artificial sweeteners. Neotame is a relatively new sweetener in the global market however there is still limited data on the impact of neotame on the intestinal epithelium or the commensal microbiota. Methods: In the present study, we use a model of the intestinal epithelium (Caco-2) and microbiota (Escherichia coli and Enterococcus faecalis) to investigate how physiologically-relevant exposure of neotame impacts intestinal epithelial cell function, gut bacterial metabolism and pathogenicity, and gut epithelium-microbiota interactions. Results: Our findings show that neotame causes intestinal epithelial cell apoptosis and death with siRNA knockdown of T1R3 expression significantly attenuating the neotame-induced loss to cell viability. Similarly, neotame exposure results in barrier disruption with enhanced monolayer leak and reduced claudin-3 cell surface expression through a T1R3-dependent pathway. Using the gut bacteria models, E. coli and E. faecalis, neotame significantly increased biofilm formation and metabolites of E. coli, but not E. faecalis, reduced Caco-2 cell viability. In co-culture studies, neotame exposure increased adhesion capacity of E. coli and E. faecalis onto Caco-2 cells and invasion capacity of E. coli. Neotame-induced biofilm formation, E.coli-specific Caco-2 cell death, adhesion and invasion was identified to be meditated through a taste-dependent pathway. Discussion: Our study identifies novel pathogenic effects of neotame on the intestinal epithelium or bacteria alone, and in co-cultures to mimic the gut microbiome. These findings demonstrate the need to better understand food additives common in the global market and the molecular mechanisms underlying potential negative health impacts.

Stability of gut microbiome after COVID-19 vaccination in healthy and immuno-compromised individuals.

Bidirectional interactions between the immune system and the gut microbiota are key contributors to various physiological functions. Immune-associated diseases such as cancer and autoimmunity, and efficacy of immunomodulatory therapies, have been linked to microbiome variation. Although COVID-19 infection has been shown to cause microbial dysbiosis, it remains understudied whether the inflammatory response associated with vaccination also impacts the microbiota. Here, we investigate the temporal impact of COVID-19 vaccination on the gut microbiome in healthy and immuno-compromised individuals; the latter included patients with primary immunodeficiency and cancer patients on immunomodulating therapies. We find that the gut microbiome remained remarkably stable post-vaccination irrespective of diverse immune status, vaccine response, and microbial composition spanned by the cohort. The stability is evident at all evaluated levels including diversity, phylum, species, and functional capacity. Our results indicate the resilience of the gut microbiome to host immune changes triggered by COVID-19 vaccination and suggest minimal, if any, impact on microbiome-mediated processes. These findings encourage vaccine acceptance, particularly when contrasted with the significant microbiome shifts observed during COVID-19 infection.

Implicit Theories of Emotional Intelligence and Students' Emotional and Academic Outcomes.

In this study, we addressed the relevance of implicit theories of emotional intelligence (ITEI) to students' emotional and academic outcomes throughout secondary school. During a three-wave longitudinal survey (10th-12th grades), 222 students, ages 14-18 years old at the first round of data collection (Mage = 15.4, SD = 0.63) and mostly female (58.6%), completed questionnaires on ITEI, emotional intelligence (EI; ability and trait), and emotions towards school. The results provided evidence for the relation of ITEI with EI (ability and trait) in the following year and their extended link with students' emotions towards school and academic achievement (Portuguese academic grade) at the end of secondary school. In addition, ability and trait EI mediated the link of entity ITEI and negative emotions and achievement. The findings suggest the importance of fostering more dynamic ITEI among students as a mean for enhancing emotional and academic outcomes.

Relationship between emotional intelligence and empathy towards humans and animals.

Previous research has highlighted that Emotional Intelligence (EI) is related to an array of positive interpersonal behaviours, including greater human empathy. Nonetheless, although animals are an integral part of our lives, there is still a lack of clarity regarding the way in which EI relates to empathy towards animals. The aim of this study was to investigate the relationship between EI and empathy towards humans and animals. We used the Trait-Meta Mood Scale to assess EI, the Interpersonal Reactivity Index to assess empathy for humans, and the Animal Empathy Scale to assess empathy for animals. Our findings revealed a positive relationship between empathy for humans and animals. The results also supported the idea that EI is positively related to empathy for humans, while the relationship between EI and empathy for animals was dependent on whether or not the participants had experience with pets. In addition, multiple regression analysis showed that the variables that best predicted empathy for animals were having a pet (or not), age, gender and human empathic concern. Finally, the relationship between human empathic concern and empathy for animals was stronger in participants who had pets. These findings provide a better understanding of the mechanisms underlying empathic behaviour and suggest that empathy for humans and animals can be influenced by different factors. Limitations and future lines of research are discussed.

Long-term complete remission of large hepatocellular adenoma after bariatric surgery.

We report the case of an obese woman with a large hepatocellular adenoma (HCA) of 8.0 cm in diameter, followed for 5 years after Roux-en-Y Gastric Bypass, with a complete radiologic remission of the liver mass. Four other cases have been published with HCA regression after bariatric surgery, but none with long-term follow-up. As the association between obesity and HCA has been increasingly described, bariatric surgery should be considered a therapeutic option for stage 2 obese patients.

Soft tissue calcifications: a pictorial essay.

Soft-tissue calcifications are extremely common. Because the imaging findings are nonspecific, soft-tissue calcifications are often problematic for radiologists, sometimes prompting unnecessary interventions. In addition, the nomenclature is quite confusing. Classically, soft-tissue calcifications are divided into four categories, by mechanism of formation-dystrophic, iatrogenic, metastatic, and idiopathic-depending on the clinical and biochemical correlation. However, it is also possible to classify such calcifications by compartment, and that classification can be quite useful in the radiological diagnostic assessment. In this article, we illustrate the main causes of soft-tissue calcifications, organizing them according to their anatomical and pathophysiological aspects, thus narrowing the differential diagnosis.

Calcificações de partes moles são achados extremamente comuns e inespecíficos nos exames de imagem e, por isso, frequentemente são fonte de confusão por parte dos radiologistas, desencadeando, por vezes, intervenções desnecessárias. Além disso, a nomenclatura atribuída é muito confusa. Classicamente, dividem-se as calcificações de partes moles, conforme seu mecanismo de formação, em calcificações distróficas, iatrogênicas, metastáticas e idiopáticas, dependendo de correlação clinicolaboratorial, porém, também é possível uma classificação compartimental das calcificações, que pode ser muito útil na propedêutica radiológica. Neste trabalho, ilustramos didaticamente as principais causas de calcificações de partes moles organizando-as de acordo com aspectos anatômicos e fisiopatológicos, estreitando os diagnósticos diferenciais.

Fighting the invisible enemy: providing support and structure to radiology resident during the COVID-19 pandemic.

The objective of this article is to share the strategy we used in order to restructure the radiology and diagnostic imaging department of a referral institution during the coronavirus disease 2019 pandemic, on the basis of the current recommendations. It is essential to integrate the work of supervisors, preceptors, and residents, maintaining communication and sharing decisions, with mutual support, as well as to determine the best strategy to be adopted in this scenario of uncertainty and constant change, while also ensuring adequate emotional support for all parties.

O objetivo deste artigo é compartilhar a estratégia de como estruturamos o departamento de radiologia e diagnóstico por imagem de uma instituição de referência na pandemia da COVID-19, baseados nas recomendações vigentes. É fundamental a integração entre supervisores, preceptores e residentes, sempre mantendo comunicação e compartilhamento das decisões, com apoio mútuo, decidindo a melhor estratégia a ser seguida neste cenário de incertezas e de mudanças contínuas, garantindo ainda suporte emocional adequado a todos.

Post-esophagectomy Symptomatic Dunbar Syndrome: A rare diagnosis of abdominal pain after surgery.

INTRODUCTION: Dunbar syndrome is a rare anatomical abnormality characterized by the extrinsic compression of the celiac trunk by the median arcuate ligament (MAL). Though it is rarely misdiagnosed, the clinical diagnosis may be difficult, especially after complex visceral surgery such as esophagectomy. PRESENTATION OF CASE: A 62-year-old male patient with a squamous cell carcinoma of the distal esophagus, placed under trimodal treatment (chemotherapy, radiotherapy followed by hybrid minimal invasive 2-field esophagectomy) presented with abdominal pain refractory to analgesics, anti-spasmodic, opioids, and neuronal celiac plexus ablation in the late post-operative period. He was diagnosed with extrinsic celiac trunk compression based on abdominal angiotomography findings. Retrospectively, similar images were found in conventional abdominal tomography at pre-operative staging, but this time, the patient had only dysphagia. After surgical treatment of MAL, the patient had total relief of pain and symptoms. DISCUSSION: Abdominal pain after complex surgical procedures is very frequent and its investigation is mandatory, even more after refractory clinical management. Dunbar syndrome is related to ambiguous abdominal pain. It is uncommon and its diagnosis with angiotomography is accessible. CONCLUSION: Vascular disorders should be investigated in cases of abdominal pain after complex surgical procedures.

Individualism and collectivism: what differences between Portuguese and Romanian adolescents?

This article presents the results of a series of preliminary comparisons, between the Portuguese and Romanian cultural contexts, on the individualism-collectivism (IND/COL) cultural dimension. The IND/COL was evaluated with the Individualism-Collectivism Questionnaire - ICQ -, constructed in New Zealand by Shulruf, Hattie and Dixon (2003, Anonymous Questionnaire of Self-Attitudes - AQSA), and adapted to the Portuguese and Romanian contexts by Ciochina and Faria (2007), using studies of confirmatory factor analysis. The ICQ composed by 26 items, 15 evaluating the IND scale--with three subscales (Uniqueness, Competition and Responsibility)--, and 11 evaluating the COL scale--with two subscales (Harmony and Advice)--, was administered to 395 subjects, 200 Portuguese and 195 Romanian, 10th and 12th graders. On the whole, in the Portuguese and Romanian samples, the multivariate and univariate statistical analyses evidenced the existence of two independent variables--gender and cultural context--, with significant effects, main and of interaction, on the scales and subscales of the ICQ. The results were discussed taking into consideration the specificities of the educational systems in the two cultural contexts, which are inevitably shaped by socio-cultural factors characteristic of the two countries considered in the present study--Portugal and Romania.

Implicit Theories of Intelligence and Academic Achievement: A Meta-Analytic Review.

The current study intended to model the link between implicit theories of intelligence (ITI) and students' academic achievement, within a meta-analytic review procedure. To assess studies' effect size, the Pearson's correlation coefficient (r) was used. The review of 46 studies (94 effect sizes) with 412,022 students presented a low-to-moderate association between the ITI and students' academic achievement. The results indicated that incremental theorists are more likely to have higher grades in specific subjects (verbal and quantitative) and in overall achievement. The entity beliefs were positively associated with students' specific verbal and quantitative domains but at a lower magnitude than incremental beliefs. Moreover, the moderator effect analyses results indicated that the link between ITI and students' achievement was not moderated by gender, but there was a moderate association in student's middle school grade. Additionally, the ITI assessment based on the most recent versions of Dweck's scales, the use of specific academic scales instead of general ITI scales, and the use of the original measures rather than adapted versions strongly moderated the link between ITI and achievement. Moreover, students from Eastern continents (Asia and Oceania) reported a positive association between incremental beliefs and achievement, Europe displayed a positive link between entity beliefs and achievement, whereas North America presented negative correlations between entity perspectives and academic achievement. This meta-analysis updates the current evidence supporting the direct link of ITI and students' academic achievement and acknowledges specific effects that ITI could have in different academic outcomes.

Personal conceptions of intelligence, self-esteem, and school achievement in Italian and Portuguese students.

Educational research places emphasis on the fact that different cultures have different self-construals. These construals can influence cognitive, emotional, and motivational processes in individuals. Great importance is attached to individuals' implicit conceptions of the nature of their intelligence (incremental or entity) and self-esteem. In general, both representation of intelligence and self-esteem seem to play an important role in scholastic performance in terms of both a predispostion to learning and the results actually achieved. The aim of this research is to determine the relationship between variables such as school, and socioeconomic level and gender in Italian and Portuguese students. A questionnaire was administered to 1,540 high school and university students assessing socioeconomic level and school performance, the Personal Conceptions of Intelligence Test (Faira & Fontaine, 1997), and the Self-Esteem Test (Rosenberg, 1965). In general, results show that Portuguese subjects are more incremental than Italians. Moreover, significant differences have to be determined regarding motivational factors linked to school and socioeconomic level and gender. The research highlights the importance of macro-contextual factors in the social, economic, and political organizations that influence how people develop their motivational beliefs.

Dimensions of causality as a function of socioeconomic status in a sample of Portuguese adolescents.

This study explored dimensions of locus of causality, stability, and controllability, of several sources for success and failure, classified by subjects as a function of their socioeconomic status. The sample included 1,320 Portuguese high school students, from high, middle, and low socioeconomic status who classified 17 causes for success and failure according to their meaning on the three dimensions. Analysis showed students from families of low socioeconomic status perceived causes related to ability, effort, and motivation as more unstable than subjects from families of middle and high socioeconomic status, and students from families of high socioeconomic status perceived causes related to ability as more internal than the other two groups.

Sex differences in the personal conceptions of intelligence: particularities of the Portuguese cultural context.

Several empirical studies have implicated helplessness as a problem in girls' lack of achievement, generally associated with static conceptions of intelligence. Yet, two studies aiming to explore sex differences in personal conceptions of intelligence, carried out with Portuguese samples of 222 and 2,106 subjects, respectively, using a 15-item rating scale to measure personal conceptions of intelligence adapted for Portuguese adolescents (11 to 17 years old), did not find sex differences, suggesting that certain specific characteristics of the Portuguese cultural context and its underlying socialization processes may have altered the expected kind of differentiation. Researchers should investigate whether success is not stereotypically attributed to male role norms and the importance of arousal of standards of achievement for women in the Portuguese culture.

Concepções Pessoais de Competência e Rendimento Acadêmico: Estudo Longitudinal no Ensino Secundário Português / Personal Conceptions of Competence and Academic Achievement: Longitudinal Study in Portuguese Secondary School

Resumo As concepções pessoais de competência (CPC) influenciam o rendimento escolar e/ou o contrário? Com base nesse questionamento, neste estudo pretendeu-se analisar a relação entre CPC (concepções pessoais de inteligência, atribuições causais, autoconceito, autoeficácia e competência emocional) e o rendimento escolar ao longo do ensino secundário, especificamente em Português. Com esse objetivo, administrou-se o Questionário Compósito de Competência Percebida (162 itens) para 433 alunos, entre os quais estão 52,8% de meninas com idade entre 14 e 18 anos (M=15,3; DP=0,63), num desenho longitudinal com três momentos separados por um ano de intervalo. Globalmente, os resultados revelaram relações recíprocas: o rendimento de um ano influenciou as CPC no ano seguinte e o autoconceito e a autoeficácia foram os principais preditores do rendimento escolar.

Abstract Do personal conceptions of competence (PCC) influence academic achievement and/or academic achievement influences PCC? In this context we sought to examine the relationship between PCC (personal conceptions of intelligence, causal attributions, self-concept, self-efficacy and emotional competence) and academic achievement throughout secondary school in Portugal. With this aim, the Composite Questionnaire of Perceived Competence (162 items) was administered to a sample of 433 students, 52.8% girls, aged between 14 and 18 years (M=15.3; SD=.63), in a three-wave longitudinal design separated by a gap of one year. Overall, the results evidenced reciprocal relationships: the achievement in the first year influenced PCC in the following year and self-concept and self-efficacy were the main predictors of academic achievement.

Parenting and Parental Involvement in Secondary School: Focus Groups with Adolescents' Parents / Parentalidade e Envolvimento Parental no Ensino Secundário: Grupos Focais com Pais de Adolescentes / Responsabilidad Parental e Envolvimiento Parental en la Educación Secundaria: Grupos Focales con Padres de Adolescentes

Abstract: Parental role in the adolescents' development is widely described as challenging, particularly regarding their involvement in school education. With the aim of examining parents' perceptions about parenting role, parental involvement and family-school partnership in the secondary school, two focus groups were conducted with parents in two public schools. Results, overall, indicate that the establishment of rules, monitoring and support were very challenging and important to the adolescents' development. Parental involvement change throughout school and several reasons were pointed out to the changes observed in secondary school: the demands of the level of education, the lack of time, adolescents' autonomy, , and teachers' communication style. Regarding family-school relations, the parents shared different experiences about the way the partnership was promoted and developed.

Resumo: O papel dos pais no desenvolvimento dos adolescentes é amplamente descrito como sendo desafiante, em particular quanto ao seu envolvimento na educação escolar. Com o objetivo de analisar as perceções de pais de adolescentes sobre o papel parental, o envolvimento parental e a parceria família-escola no ensino secundário foram conduzidos dois grupos focais em duas escolas públicas. Os resultados, globalmente, indicam que o estabelecimento de regras, a monitorização e o apoio são funções parentais desafiantes e importantes no desenvolvimento dos adolescentes. O envolvimento parental altera-se durante a escolaridade e várias razões foram apontadas para as mudanças no ensino secundário: as exigências deste nível de escolaridade, a falta de tempo, a autonomização dos adolescentes e o estilo de comunicação dos professores. Quanto às relações família-escola, os pais partilharam experiências diferenciadas sobre a promoção e desenvolvimento desta parceria.

Resumen: El papel de los padres en el desarrollo de los adolescentes es ampliamente descrito como desafiante, especialmente su participación en la educación escolar. Con objeto de analizar la percepción de los padres sobre la responsabilidad parental, el envolvimiento de los padres y la colaboración familia-escuela en la educación secundaria, se realizaron dos grupos focales en dos escuelas publicas. Los resultados globalmente indican que el establecimiento de normas, la supervisión y el apoyo son funciones parentales desafiantes e importantes en el desarrollo de los adolescentes. El involucramiento parental se altera durante la escolarización y varias razones fueron apuntadas para los cambios en la educación secundaria: las exigencias de este nivel de educación, la falta de tiempo, la autonomía de los adolescentes y el estilo de comunicación de los profesores. Respecto a las relaciones familia-escuela, los padres compartieron diferentes experiencias en la promoción y desarrollo de esta alianza.