Omphalocele: clinical and epidemiological profile of patients born in a tertiary care center in Rio de Janeiro.

BACKGROUND: The objective of this paper is to describe the clinical and epidemiological profile and the early outcomes of patients with omphalocele born in a fetal medicine, pediatric surgery, and genetics reference hospital in Rio de Janeiro - Brazil. To determine its prevalence, describe the presence of genetic syndromes, and congenital malformations, emphasizing the characteristics of congenital heart diseases and their most common types. METHODS: Using Latin-American Collaborative Study of Congenital Malformations (ECLAMC) database and records review, a retrospective cross-sectional study was performed, including all patients born with omphalocele between January 1st, 2016, and December 31st, 2019. RESULTS: During the period of the study, our unity registered 4,260 births, 4,064 were live births and 196 stillbirths. There were 737 diagnoses of any congenital malformation, among them 38 cases of omphalocele, 27 were live born, but one was excluded for missing data. 62.2% were male, 62.2% of the women were multiparous and 51.3% of the babies were preterm. There was an associated malformation in 89.1% of the cases. Heart disease was the most common (45.9%) of which tetralogy of Fallot was the most frequent (23.5%). Mortality rate was 61.5%. CONCLUSIONS: Our data showed a good correspondence with the existing literature. Most patients with omphalocele had other malformations, especially congenital heart disease. No pregnancy was interrupted. The presence of concurrent defects showed a huge impact on prognosis, since, even if most survived birth, few remained alive and received hospital discharge. Based on these data, fetal medicine and neonatal teams must be able to adjust parents counseling about fetal and neonatal risks, especially when other congenital diseases are present.

Multiple bee stings, multiple organs involved: a case report.

Accidents related to Africanized honey bees are growing globally and are associated with multiple stings owing to the aggressive behavior of this species. The massive inoculation of venom causes skin necrosis and rhabdomyolysis leading to renal failure. Anaphylactic manifestations are more common and are treated using well-defined treatment protocols. However, bee venom-induced toxic reactions may be serious and require a different approach. We report the case of a 3-year-old child, which would help clinicians to focus on the treatment approach required after an incident involving multiple bee stings.

Multiple bee stings, multiple organs involved: a case report

Abstract Accidents related to Africanized honey bees are growing globally and are associated with multiple stings owing to the aggressive behavior of this species. The massive inoculation of venom causes skin necrosis and rhabdomyolysis leading to renal failure. Anaphylactic manifestations are more common and are treated using well-defined treatment protocols. However, bee venom-induced toxic reactions may be serious and require a different approach. We report the case of a 3-year-old child, which would help clinicians to focus on the treatment approach required after an incident involving multiple bee stings.

Infecção hospitalar em uma unidade de cuidados intensivos em pós-operatório de cirurgia cardíaca infantil / Hospital infection in a pediatric cardiac surgery post operative intensive care unit

Fundamentos: A infecção relacionada à assistência à saúde (IRAS) é causa importante de morbidade e mortalidade nos pacientes pediátricos submetidos à cirurgia cardíaca. Objetivo: Avaliar as infecções hospitalares e os fatores de risco associados em uma unidade de pós-operatório de cirurgia cardíaca infantil no período de janeiro a dezembro de 2008. Método: Estudo tipo caso-controle (1:2). Com pareamento pelo trimestre de internação, totalizando 44 casos e 88 controles. Resultados: A taxa de incidência de IRAS foi 42/251 pacientes (16,7 porcento). A taxa de IRAS relacionada à cirurgia foi 44/254 (17,3 porcento). Nos casos 24/44 (54,5 porcento) eram do sexo masculino, e a mediana do peso foi 6.335g. Quanto à faixa etária, havia 21/44 (47,7 porcento) lactentes e 18/44 (40,9 porcento) pré-escolares. Na análise univariada as variáveis estatisticamente significativa foram: Escore Aristóteles de Complexidade Básica (ABC), presença de síndrome de Down, uso de antibiótico prévio, uso de hemoderivados, e tempos de internação, de circulação extracorpórea, de clampeamento aórtico, de ventilação mecânica, de cateter venoso central, e de drenos. Os fatores de risco independentes para IRAS foram: escore ABC > 2; presença de síndrome de Down; uso de antibiótico prévio e hemoderivados no peroperatório. A sepse clínica ocorreu em 23 casos, 3 casos com confirmação laboratorial. Pneumonia clínica em 12 e infecção de sítio cirúrgico em 8 casos. O microorganismo mais frequente foi o cocco Gram positivo. Conclusão: Existe uma associação entre IRAS e uso prévio de antibióticos, assim como escore de complexidade cirúrgica, uso de hemoderivados, presença de síndrome de Down e tempo de uso de dispositivos invasivos.