Detalhe da pesquisa
1.
Loss of endocytosis-associated RabGEF1 causes aberrant morphogenesis and altered autophagy in photoreceptors leading to retinal degeneration.
PLoS Genet
; 16(12): e1009259, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33362196
2.
REEP6 mediates trafficking of a subset of Clathrin-coated vesicles and is critical for rod photoreceptor function and survival.
Hum Mol Genet
; 26(12): 2218-2230, 2017 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28369466
3.
Requirement for Microglia for the Maintenance of Synaptic Function and Integrity in the Mature Retina.
J Neurosci
; 36(9): 2827-42, 2016 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26937019
4.
CEP290 alleles in mice disrupt tissue-specific cilia biogenesis and recapitulate features of syndromic ciliopathies.
Hum Mol Genet
; 24(13): 3775-91, 2015 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25859007
5.
Age-related macular degeneration: genetics and biology coming together.
Annu Rev Genomics Hum Genet
; 15: 151-71, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24773320
6.
Dnmt1, Dnmt3a and Dnmt3b cooperate in photoreceptor and outer plexiform layer development in the mammalian retina.
Exp Eye Res
; 159: 132-146, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27865785
7.
Microglial phagocytosis and activation underlying photoreceptor degeneration is regulated by CX3CL1-CX3CR1 signaling in a mouse model of retinitis pigmentosa.
Glia
; 64(9): 1479-91, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27314452
8.
Rare and common variants in extracellular matrix gene Fibrillin 2 (FBN2) are associated with macular degeneration.
Hum Mol Genet
; 23(21): 5827-37, 2014 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24899048
9.
Conditional knockdown of DNA methyltransferase 1 reveals a key role of retinal pigment epithelium integrity in photoreceptor outer segment morphogenesis.
Development
; 140(6): 1330-41, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23406904
10.
Macroglia-microglia interactions via TSPO signaling regulates microglial activation in the mouse retina.
J Neurosci
; 34(10): 3793-806, 2014 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24599476
11.
Development and plasticity of outer retinal circuitry following genetic removal of horizontal cells.
J Neurosci
; 33(45): 17847-62, 2013 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-24198374
12.
Preservation of cone photoreceptors after a rapid yet transient degeneration and remodeling in cone-only Nrl-/- mouse retina.
J Neurosci
; 32(2): 528-41, 2012 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22238088
13.
Probing potassium channel function in vivo by intracellular delivery of antibodies in a rat model of retinal neurodegeneration.
Proc Natl Acad Sci U S A
; 107(28): 12710-5, 2010 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-20616020
14.
PDGF-CC blockade inhibits pathological angiogenesis by acting on multiple cellular and molecular targets.
Proc Natl Acad Sci U S A
; 107(27): 12216-21, 2010 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-20566880
15.
Advances in understanding the molecular structure of retinoschisin while questions remain of biological function.
Prog Retin Eye Res
; 95: 101147, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-36402656
16.
Minocycline attenuates photoreceptor degeneration in a mouse model of subretinal hemorrhage microglial: inhibition as a potential therapeutic strategy.
Am J Pathol
; 179(3): 1265-77, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21763674
17.
Targeted Expression of Retinoschisin by Retinal Bipolar Cells in XLRS Promotes Resolution of Retinoschisis Cysts Sans RS1 From Photoreceptors.
Invest Ophthalmol Vis Sci
; 63(11): 8, 2022 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36227606
18.
Adaptive Müller cell responses to microglial activation mediate neuroprotection and coordinate inflammation in the retina.
J Neuroinflammation
; 8: 173, 2011 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22152278
19.
Effective tumor treatment targeting a melanoma/melanocyte-associated antigen triggers severe ocular autoimmunity.
Proc Natl Acad Sci U S A
; 105(23): 8061-6, 2008 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-18523011
20.
Genetic Rescue of X-Linked Retinoschisis Mouse (Rs1-/y) Retina Induces Quiescence of the Retinal Microglial Inflammatory State Following AAV8-RS1 Gene Transfer and Identifies Gene Networks Underlying Retinal Recovery.
Hum Gene Ther
; 32(13-14): 667-681, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33019822