Detalhe da pesquisa
1.
Discovery of liver-targeted inhibitors of stearoyl-CoA desaturase (SCD1).
Bioorg Med Chem Lett
; 23(3): 791-6, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23265904
2.
Discovery of novel orally active ureido NPY Y5 receptor antagonists.
Bioorg Med Chem Lett
; 18(3): 1146-50, 2008 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18160282
3.
Discovery of orally efficacious melanin-concentrating hormone receptor-1 antagonists as antiobesity agents. Synthesis, SAR, and biological evaluation of bicyclo[3.1.0]hexyl ureas.
J Med Chem
; 49(7): 2294-310, 2006 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-16570926
4.
Effects of a selective melanin-concentrating hormone 1 receptor antagonist on food intake and energy homeostasis in diet-induced obese mice.
Eur J Pharmacol
; 535(1-3): 182-91, 2006 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-16540104
5.
Biaryl ureas as potent and orally efficacious melanin concentrating hormone receptor 1 antagonists for the treatment of obesity.
J Med Chem
; 48(15): 4746-9, 2005 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-16033253
6.
Ezetimibe potently inhibits cholesterol absorption but does not affect acute hepatic or intestinal cholesterol synthesis in rats.
Br J Pharmacol
; 138(8): 1459-64, 2003 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-12721101
7.
Melanin-concentrating hormone-1 receptor antagonism decreases feeding by reducing meal size.
Eur J Pharmacol
; 497(1): 41-7, 2004 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-15321733
8.
Discovery of SCH 900271, a Potent Nicotinic Acid Receptor Agonist for the Treatment of Dyslipidemia.
ACS Med Chem Lett
; 3(1): 63-8, 2012 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900372
9.
Discovery of a potent nicotinic Acid receptor agonist for the treatment of dyslipidemia.
ACS Med Chem Lett
; 2(2): 171-6, 2011 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900295
10.
Meal pattern analysis of diet-induced obesity in susceptible and resistant rats.
Obes Res
; 11(7): 845-51, 2003 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12855753
11.
Fat intake affects adiposity, comorbidity factors, and energy metabolism of sprague-dawley rats.
Obes Res
; 10(9): 956-63, 2002 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-12226145