Detalhe da pesquisa
1.
Design, synthesis, and evaluation of proline and pyrrolidine based melanocortin receptor agonists. A conformationally restricted dipeptide mimic approach.
J Med Chem
; 49(15): 4745-61, 2006 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-16854081
2.
Comparison of high throughput screening technologies for luminescence cell-based reporter screens.
J Biomol Screen
; 7(1): 67-77, 2002 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-11897057
3.
Discovery of orally bioavailable 1,3,4-trisubstituted 2-oxopiperazine-based melanocortin-4 receptor agonists as potential antiobesity agents.
J Med Chem
; 51(19): 6055-66, 2008 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-18771254
4.
Synthesis of Tic-D-Phe Psi[CH2-CH2] isostere and its use in the development of melanocortin receptor agonists.
Bioorg Med Chem Lett
; 16(6): 1721-5, 2006 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16376076
5.
Design and synthesis of potent and selective 1,3,4-trisubstituted-2-oxopiperazine based melanocortin-4 receptor agonists.
Bioorg Med Chem Lett
; 16(17): 4668-73, 2006 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16766182
6.
1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors.
Bioorg Med Chem Lett
; 16(6): 1574-8, 2006 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16386905