Detalhe da pesquisa
1.
Structural basis of specific inhibition of extracellular activation of pro- or latent myostatin by the monoclonal antibody SRK-015.
J Biol Chem
; 295(16): 5404-5418, 2020 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32075906
2.
Nonclinical Development of SRK-181: An Anti-Latent TGFß1 Monoclonal Antibody for the Treatment of Locally Advanced or Metastatic Solid Tumors.
Int J Toxicol
; 40(3): 226-241, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33739172
3.
Inhibiting Plasma Kallikrein for Hereditary Angioedema Prophylaxis.
N Engl J Med
; 376(8): 717-728, 2017 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28225674
4.
Inhibition of plasma kallikrein by a highly specific active site blocking antibody.
J Biol Chem
; 289(34): 23596-608, 2014 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24970892
5.
A phase 1 study investigating DX-2930 in healthy subjects.
Ann Allergy Asthma Immunol
; 113(4): 460-6.e2, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24980392
6.
Selective inhibition of TGFß1 activation overcomes primary resistance to checkpoint blockade therapy by altering tumor immune landscape.
Sci Transl Med
; 12(536)2020 03 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32213632
7.
2D-LC-MS/MS to measure cleaved high-molecular-weight kininogen in human plasma as a biomarker for C1-INH-HAE.
Bioanalysis
; 9(19): 1477-1491, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-29056074
8.
Intergenerational transmission of glucose intolerance and obesity by in utero undernutrition in mice.
Diabetes
; 58(2): 460-8, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19017762
9.
Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation.
J Biol Chem
; 282(21): 15439-50, 2007 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-17416903