Detalhe da pesquisa
1.
Stepwise requirements for polymerases δ and θ in theta-mediated end joining.
Nature
; 623(7988): 836-841, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37968395
2.
BRCA1 Mutational Complementation Induces Synthetic Viability.
Mol Cell
; 78(5): 951-959.e6, 2020 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32359443
3.
DNA polymerase θ protects leukemia cells from metabolically induced DNA damage.
Blood
; 141(19): 2372-2389, 2023 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36580665
4.
Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks.
Mol Cell
; 63(4): 662-673, 2016 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27453047
5.
Marker-free quantification of repair pathway utilization at Cas9-induced double-strand breaks.
Nucleic Acids Res
; 49(9): 5095-5105, 2021 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33963863
6.
Mechanistic basis for microhomology identification and genome scarring by polymerase theta.
Proc Natl Acad Sci U S A
; 117(15): 8476-8485, 2020 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32234782
7.
ATM-dependent Phosphorylation of the Fanconi Anemia Protein PALB2 Promotes the DNA Damage Response.
J Biol Chem
; 290(46): 27545-56, 2015 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-26420486
8.
Ring finger protein RNF169 antagonizes the ubiquitin-dependent signaling cascade at sites of DNA damage.
J Biol Chem
; 287(33): 27715-22, 2012 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22733822
9.
Genetic separation of Brca1 functions reveal mutation-dependent Polθ vulnerabilities.
Nat Commun
; 14(1): 7714, 2023 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38001070
10.
Targeting Non-homologous and Alternative End Joining Repair to Enhance Cancer Radiosensitivity.
Semin Radiat Oncol
; 32(1): 29-41, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34861993
11.
Poly(ADP) ribose polymerase promotes DNA polymerase theta-mediated end joining by activation of end resection.
Nat Commun
; 13(1): 4547, 2022 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35927262
12.
Dual inhibition of DNA-PK and DNA polymerase theta overcomes radiation resistance induced by p53 deficiency.
NAR Cancer
; 2(4): zcaa038, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33385162
13.
Genetic determinants of cellular addiction to DNA polymerase theta.
Nat Commun
; 10(1): 4286, 2019 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31537809
14.
BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance.
Cell Rep
; 24(13): 3513-3527.e7, 2018 09 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30257212
15.
A new amplification strategy for ultrasensitive electrochemical aptasensor with network-like thiocyanuric acid/gold nanoparticles.
Biosens Bioelectron
; 23(3): 341-7, 2007 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-17583489
16.
TRAIP regulates replication fork recovery and progression via PCNA.
Cell Discov
; 2: 16016, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27462463
17.
BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance.
Cell Rep
; 25(5): 1384, 2018 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30380426
18.
RAB-27 and its effector RBF-1 regulate the tethering and docking steps of DCV exocytosis in C. elegans.
Sci China Life Sci
; 55(3): 228-35, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22527519