Detalhe da pesquisa
1.
Myeloid ERK5 deficiency suppresses tumor growth by blocking protumor macrophage polarization via STAT3 inhibition.
Proc Natl Acad Sci U S A
; 115(12): E2801-E2810, 2018 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29507229
2.
Hypoxia and hyperglycaemia determine why some endometrial tumours fail to respond to metformin.
Br J Cancer
; 122(1): 62-71, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31819173
3.
Inhibiting ERK5 overcomes breast cancer resistance to anti-HER2 therapy by targeting the G1/S cell cycle transition.
Cancer Res Commun
; 2(3): 131-145, 2022 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36466034
4.
The extracellular-regulated protein kinase 5 (ERK5) enhances metastatic burden in triple-negative breast cancer through focal adhesion protein kinase (FAK)-mediated regulation of cell adhesion.
Oncogene
; 40(23): 3929-3941, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33981002
5.
Identification and Validation of ERK5 as a DNA Damage Modulating Drug Target in Glioblastoma.
Cancers (Basel)
; 13(5)2021 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33668183
6.
Extracellular-Regulated Protein Kinase 5-Mediated Control of p21 Expression Promotes Macrophage Proliferation Associated with Tumor Growth and Metastasis.
Cancer Res
; 80(16): 3319-3330, 2020 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32561530
7.
Targeting the MAPK7/MMP9 axis for metastasis in primary bone cancer.
Oncogene
; 39(33): 5553-5569, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32655131
8.
Targeted deletion of mek5 causes early embryonic death and defects in the extracellular signal-regulated kinase 5/myocyte enhancer factor 2 cell survival pathway.
Mol Cell Biol
; 25(1): 336-45, 2005 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-15601854
9.
The regulation of Bax by c-Jun N-terminal protein kinase (JNK) is a prerequisite to the mitochondrial-induced apoptotic pathway.
FEBS Lett
; 580(5): 1320-6, 2006 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-16458303
10.
Oxygen-Enhanced MRI Accurately Identifies, Quantifies, and Maps Tumor Hypoxia in Preclinical Cancer Models.
Cancer Res
; 76(4): 787-95, 2016 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26659574
11.
ERK5 is a critical mediator of inflammation-driven cancer.
Cancer Res
; 75(4): 742-53, 2015 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25649771
12.
Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma.
Cancer Res
; 74(12): 3344-56, 2014 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24713432
13.
The extracellular-regulated protein kinase 5 (ERK5) promotes cell proliferation through the down-regulation of inhibitors of cyclin dependent protein kinases (CDKs).
Cell Signal
; 24(12): 2360-8, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22917534
14.
The mitogen-activated protein kinase kinase 4 has a pro-oncogenic role in skin cancer.
Cancer Res
; 70(14): 5797-806, 2010 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20610622