Detalhe da pesquisa
1.
Kernel-Based, Partial Least Squares Quantitative Structure-Retention Relationship Model for UPLC Retention Time Prediction: A Useful Tool for Metabolite Identification.
Anal Chem
; 88(19): 9510-9517, 2016 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27583774
2.
Discovery of NMS-E973 as novel, selective and potent inhibitor of heat shock protein 90 (Hsp90).
Bioorg Med Chem
; 21(22): 7047-63, 2013 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24100158
3.
Application of an "inhalation by design" approach to the identification and in-vitro evaluation of novel purine based PI3Kδ inhibitors.
Eur J Med Chem
; 254: 115331, 2023 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37094451
4.
Structure-based optimization of potent PDK1 inhibitors.
Bioorg Med Chem Lett
; 20(14): 4095-9, 2010 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20621725
5.
Discovery of Entrectinib: A New 3-Aminoindazole As a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor.
J Med Chem
; 59(7): 3392-408, 2016 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27003761
6.
Correction to Discovery of Entrectinib: A New 3-Aminoindazole as a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor.
J Med Chem
; 62(17): 8364, 2019 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31424209
7.
Synthesis and structure-activity relationship studies of O-biphenyl-3-yl carbamates as peripherally restricted fatty acid amide hydrolase inhibitors.
J Med Chem
; 56(14): 5917-30, 2013 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23822179
8.
Synthesis and structure-activity relationship (SAR) of 2-methyl-4-oxo-3-oxetanylcarbamic acid esters, a class of potent N-acylethanolamine acid amidase (NAAA) inhibitors.
J Med Chem
; 56(17): 6917-34, 2013 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23991897
9.
Asymmetric synthesis of delta-substituted alpha,beta-unsaturated delta-lactams by ring closing metathesis of enantiomerically pure N-acryloyl-homoallylic amines.
J Org Chem
; 72(16): 6022-8, 2007 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-17625880
10.
Asymmetric synthesis of 2-(2-pyridyl)aziridines from 2-pyridineimines bearing stereogenic N-alkyl substituents and regioselective opening of the aziridine ring.
J Org Chem
; 71(25): 9373-81, 2006 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-17137364