Detalhe da pesquisa
1.
Cognitive dysfunction and increased phosphorylated tau are associated with reduced O-GlcNAc signaling in an aging mouse model of metabolic syndrome.
J Neurosci Res
; 101(8): 1324-1344, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37031439
2.
Irisin treatment lowers levels of phosphorylated tau in the hippocampus of pre-symptomatic female but not male htau mice.
Neuropathol Appl Neurobiol
; 47(7): 967-978, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33768561
3.
Pharmacological inhibition of CSF1R by GW2580 reduces microglial proliferation and is protective against neuroinflammation and dopaminergic neurodegeneration.
FASEB J
; 34(1): 1679-1694, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31914683
4.
Developmental exposure to the organochlorine pesticide dieldrin causes male-specific exacerbation of α-synuclein-preformed fibril-induced toxicity and motor deficits.
Neurobiol Dis
; 141: 104947, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32422283
5.
Time course and magnitude of alpha-synuclein inclusion formation and nigrostriatal degeneration in the rat model of synucleinopathy triggered by intrastriatal α-synuclein preformed fibrils.
Neurobiol Dis
; 130: 104525, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31276792
6.
Atp13a2-deficient mice exhibit neuronal ceroid lipofuscinosis, limited α-synuclein accumulation and age-dependent sensorimotor deficits.
Hum Mol Genet
; 22(10): 2067-82, 2013 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23393156
7.
Chronic administration of cholesterol oximes in mice increases transcription of cytoprotective genes and improves transcriptome alterations induced by alpha-synuclein overexpression in nigrostriatal dopaminergic neurons.
Neurobiol Dis
; 69: 263-75, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24844147
8.
Role of rodent models in advancing precision medicine for Parkinson's disease.
Handb Clin Neurol
; 193: 3-16, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36803818
9.
ATP13A2 (PARK9) and basal ganglia function.
Front Neurol
; 14: 1252400, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38249738
10.
iPSC-derived neural precursor cells engineering GBA1 recovers acid ß-glucosidase deficiency and diminishes α-synuclein and neuropathology.
Mol Ther Methods Clin Dev
; 29: 185-201, 2023 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37063480
11.
Cognitive deficits in a mouse model of pre-manifest Parkinson's disease.
Eur J Neurosci
; 35(6): 870-82, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22356593
12.
A pilot trial of the microtubule-interacting peptide (NAP) in mice overexpressing alpha-synuclein shows improvement in motor function and reduction of alpha-synuclein inclusions.
Mol Cell Neurosci
; 46(3): 597-606, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21193046
13.
Secretion of amyloidogenic gelsolin progressively compromises protein homeostasis leading to the intracellular aggregation of proteins.
Proc Natl Acad Sci U S A
; 106(27): 11125-30, 2009 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-19549824
14.
Targeting alpha-synuclein via the immune system in Parkinson's disease: Current vaccine therapies.
Neuropharmacology
; 202: 108870, 2022 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34742741
15.
Farey Trees Explain Sequential Effects in Choice Response Time.
Front Physiol
; 12: 611145, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33815133
16.
Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant alpha-synuclein.
J Neurosci
; 29(7): 1962-76, 2009 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-19228951
17.
Cinnamon in a mouse model of PD: Khasnavis S, Pahan K. Cinnamon protects dopaminergic neurons in a mouse model of Parkinson's disease. J Neuroimmune Pharmacol 2014;9:569-581.
Mov Disord
; 29(12): 1466, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25284437
18.
Ribosomal s15: A novel therapeutic target for Parkinson's disease.
Mov Disord
; 29(8): 990, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24865568
19.
Olfactory deficits in mice overexpressing human wildtype alpha-synuclein.
Eur J Neurosci
; 28(2): 247-56, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18702696
20.
Abnormal colonic motility in mice overexpressing human wild-type alpha-synuclein.
Neuroreport
; 19(8): 873-6, 2008 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-18463504