Detalhe da pesquisa
1.
Discovery of fluorobenzimidazole HCV NS5A inhibitors.
Bioorg Med Chem Lett
; 26(22): 5462-5467, 2016 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27780635
2.
Aryl uracil inhibitors of hepatitis C virus NS5B polymerase: synthesis and characterization of analogs with a fused 5,6-bicyclic ring motif.
Bioorg Med Chem Lett
; 23(12): 3487-90, 2013 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23664214
3.
Identification of aryl dihydrouracil derivatives as palm initiation site inhibitors of HCV NS5B polymerase.
Bioorg Med Chem Lett
; 22(11): 3747-50, 2012 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22542020
4.
Hepatitis C NS5B polymerase inhibitors: functional equivalents for the benzothiadiazine moiety.
Bioorg Med Chem Lett
; 21(6): 1876-9, 2011 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21316235
5.
Synthesis and evaluation of inhibitors of cytochrome P450 3A (CYP3A) for pharmacokinetic enhancement of drugs.
Bioorg Med Chem Lett
; 19(18): 5444-8, 2009 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19679477
6.
Highlights of the Structure-Activity Relationships of Benzimidazole Linked Pyrrolidines Leading to the Discovery of the Hepatitis C Virus NS5A Inhibitor Pibrentasvir (ABT-530).
J Med Chem
; 61(9): 4052-4066, 2018 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29653491
7.
2-Pyridyl P1'-substituted symmetry-based human immunodeficiency virus protease inhibitors (A-792611 and A-790742) with potential for convenient dosing and reduced side effects.
J Med Chem
; 52(8): 2571-86, 2009 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-19323562
8.
Synthesis and biological characterization of B-ring amino analogues of potent benzothiadiazine hepatitis C virus polymerase inhibitors.
J Med Chem
; 52(10): 3174-83, 2009 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-19402666
9.
Synthesis, antiviral activity, and pharmacokinetic evaluation of P3 pyridylmethyl analogs of oximinoarylsulfonyl HIV-1 protease inhibitors.
Bioorg Med Chem
; 14(12): 4035-46, 2006 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16504523
10.
Oximinoarylsulfonamides as potent HIV protease inhibitors.
Bioorg Med Chem Lett
; 15(9): 2275-8, 2005 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-15837308