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Photochem Photobiol ; 88(6): 1507-12, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-22762563

RESUMO

The objective of this study was to evaluate the effect of reduced sun exposure of outdoor workers on vitamin D status using different modalities of sun protection, for primary prevention of skin cancer. 25-OH-D3 measurements were performed in two successive winters, 8 (interim) and 20 months after initiation of the study, in three groups of male outdoor workers, enrolled in either a complete, partial or minimal sun protection program. Ambient solar UVB radiation was monitored simultaneously. No intragroup or intergroup differences were observed between the interim- and postintervention measurements of mean 25-OH-D3, which were close to 30 ng mL(-1). Significant risk factors for postintervention 25-OH-D3 levels >33.8 ng mL(-1) (a surrogate for reduced sun protection) were: previous sunburn episodes (OR 2.5; 95% CI 1.01-6.3; P=0.05) and younger age (OR 0.92; 95 CI 0.86-0.98; P=0.009). Outdoor workers of Western, compared with those of Eastern paternal origin had a borderline significant risk (OR 2.4; 95% CI 0.9-6.3; P=0.07). A borderline significant effect (OR 2.9; 95% CI 0.97-10.1; P=0.085) was also noted for those in the minimal intervention group. In conclusion, sun protection among outdoor workers following a successful intervention did not suppress mean winter 25-OH-D3.


Assuntos
Calcifediol/sangue , Protetores Solares/farmacologia , Adulto , Envelhecimento , Humanos , Israel , Masculino , Pessoa de Meia-Idade , Análise Multivariada , Exposição Ocupacional , Razão de Chances , Queimadura Solar/prevenção & controle , Protetores Solares/administração & dosagem
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