RESUMO
Artificial intelligence (AI) readers of mammograms compare favourably to individual radiologists in detecting breast cancer. However, AI readers cannot perform at the level of multi-reader systems used by screening programs in countries such as Australia, Sweden, and the UK. Therefore, implementation demands human-AI collaboration. Here, we use a large, high-quality retrospective mammography dataset from Victoria, Australia to conduct detailed simulations of five potential AI-integrated screening pathways, and examine human-AI interaction effects to explore automation bias. Operating an AI reader as a second reader or as a high confidence filter improves current screening outcomes by 1.9-2.5% in sensitivity and up to 0.6% in specificity, achieving 4.6-10.9% reduction in assessments and 48-80.7% reduction in human reads. Automation bias degrades performance in multi-reader settings but improves it for single-readers. This study provides insight into feasible approaches for AI-integrated screening pathways and prospective studies necessary prior to clinical adoption.
Assuntos
Inteligência Artificial , Neoplasias da Mama , Detecção Precoce de Câncer , Mamografia , Humanos , Neoplasias da Mama/diagnóstico por imagem , Neoplasias da Mama/diagnóstico , Feminino , Mamografia/métodos , Detecção Precoce de Câncer/métodos , Estudos Retrospectivos , Pessoa de Meia-Idade , Vitória/epidemiologia , Idoso , Programas de Rastreamento/métodos , Sensibilidade e EspecificidadeRESUMO
Supplemental material is available for this article. Keywords: Mammography, Screening, Convolutional Neural Network (CNN) Published under a CC BY 4.0 license. See also the commentary by Cadrin-Chênevert in this issue.