Detalhe da pesquisa
1.
Machine learning for subtype definition and risk prediction in heart failure, acute coronary syndromes and atrial fibrillation: systematic review of validity and clinical utility.
BMC Med
; 19(1): 85, 2021 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33820530
2.
Leveraging Human Genetics to Estimate Clinical Risk Reductions Achievable by Inhibiting Factor XI.
Stroke
; 50(11): 3004-3012, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31558144
3.
Neutrophil-mediated IL-6 receptor trans-signaling and the risk of chronic obstructive pulmonary disease and asthma.
Hum Mol Genet
; 26(8): 1584-1596, 2017 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28334838
4.
Functional IL6R 358Ala allele impairs classical IL-6 receptor signaling and influences risk of diverse inflammatory diseases.
PLoS Genet
; 9(4): e1003444, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23593036
5.
Inflammatory cytokines and risk of coronary heart disease: new prospective study and updated meta-analysis.
Eur Heart J
; 35(9): 578-89, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24026779
6.
Association of Cardiometabolic Multimorbidity With Mortality.
JAMA
; 314(1): 52-60, 2015 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26151266
7.
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies.
Lancet
; 379(9822): 1205-13, 2012 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-22421339
8.
Prevalence, phenotypic characteristics and prognostic role of apparent treatment resistant hypertension in the German Chronic Kidney Disease (GCKD) study.
J Hum Hypertens
; 37(5): 345-353, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35534618
9.
Environmental and genetic predictors of human cardiovascular ageing.
Nat Commun
; 14(1): 4941, 2023 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37604819
10.
Combined targeting of lentiviral vectors and positioning of transduced cells by magnetic nanoparticles.
Proc Natl Acad Sci U S A
; 106(1): 44-9, 2009 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-19118196
11.
Investigation into the Health Effects of Reduced Chymase Function Using Predicted Loss-of-Function Mutations in CMA1.
J Cardiovasc Transl Res
; 15(6): 1474-1476, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35513594
12.
Genetic and environmental determinants of diastolic heart function.
Nat Cardiovasc Res
; 1(4): 361-371, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35479509
13.
Rare genetic variants affecting urine metabolite levels link population variation to inborn errors of metabolism.
Nat Commun
; 12(1): 964, 2021 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33574263
14.
The role of machine learning in clinical research: transforming the future of evidence generation.
Trials
; 22(1): 537, 2021 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34399832
15.
Mendelian randomization for studying the effects of perturbing drug targets.
Wellcome Open Res
; 6: 16, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33644404
16.
Genetic drug target validation using Mendelian randomisation.
Nat Commun
; 11(1): 3255, 2020 06 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32591531
17.
Differential regulation of protein subdomain activity with caged bivalent ligands.
Chembiochem
; 10(4): 654-7, 2009 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-19189364
18.
Genetic effects on promoter usage are highly context-specific and contribute to complex traits.
Elife
; 82019 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30618377
19.
Interleukin-6 Receptor Signaling and Abdominal Aortic Aneurysm Growth Rates.
Circ Genom Precis Med
; 12(2): e002413, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30657332
20.
Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis.
JAMA Cardiol
; 3(7): 619-627, 2018 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29926099