Detalhe da pesquisa
1.
Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis.
Proc Natl Acad Sci U S A
; 119(13): e2023784119, 2022 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35333654
2.
The multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities.
Nucleic Acids Res
; 50(22): 13063-13082, 2022 12 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36464162
3.
Diversity of Quaternary Structures Regulates Nuclear Receptor Activities.
Trends Biochem Sci
; 44(1): 2-6, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30293659
4.
Priming of SARS-CoV-2 S protein by several membrane-bound serine proteinases could explain enhanced viral infectivity and systemic COVID-19 infection.
J Biol Chem
; 296: 100135, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33268377
5.
Beyond copy number: A new, rapid, and versatile method for sequencing the entire SMN2 gene in SMA patients.
Hum Mutat
; 42(6): 787-795, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33739559
6.
A new de novo SYT2 mutation presenting as distal weakness. Neuropathy or neuromuscular junction dysfunction?
J Peripher Nerv Syst
; 26(1): 113-117, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33320396
7.
K Domain CR9 of Low Density Lipoprotein (LDL) Receptor-related Protein 1 (LRP1) Is Critical for Aggregated LDL-induced Foam Cell Formation from Human Vascular Smooth Muscle Cells.
J Biol Chem
; 290(24): 14852-65, 2015 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25918169
8.
Unique thrombin inhibition mechanism by anophelin, an anticoagulant from the malaria vector.
Proc Natl Acad Sci U S A
; 109(52): E3649-58, 2012 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23223529
9.
Structural and functional analysis of APOA5 mutations identified in patients with severe hypertriglyceridemia.
J Lipid Res
; 54(3): 649-661, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23307945
10.
Structural basis of thrombin-mediated factor V activation: the Glu666-Glu672 sequence is critical for processing at the heavy chain-B domain junction.
Blood
; 117(26): 7164-73, 2011 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-21555742
11.
Structure and function analysis of Sam68 and hnRNP A1 synergy in the exclusion of exon 7 from SMN2 transcripts.
Protein Sci
; 32(4): e4553, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36560896
12.
A hotspot for posttranslational modifications on the androgen receptor dimer interface drives pathology and anti-androgen resistance.
Sci Adv
; 9(11): eade2175, 2023 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36921044
13.
Potent phagocytic activity with impaired antigen presentation identifying lipopolysaccharide-tolerant human monocytes: demonstration in isolated monocytes from cystic fibrosis patients.
J Immunol
; 182(10): 6494-507, 2009 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19414804
14.
Novel PLEKHG5 mutations in a patient with childhood-onset lower motor neuron disease.
Ann Clin Transl Neurol
; 8(1): 294-299, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33275839
15.
Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation.
Nature
; 425(6957): 535-9, 2003 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-14523451
16.
Practical guidelines to manage discordant situations of SMN2 copy number in patients with spinal muscular atrophy.
Neurol Genet
; 6(6): e530, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33324756
17.
Mutation update of spinal muscular atrophy in Spain: molecular characterization of 745 unrelated patients and identification of four novel mutations in the SMN1 gene.
Hum Genet
; 125(1): 29-39, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19050931
18.
Contribution of globular death domains and unstructured linkers to MyD88.IRAK-4 heterodimer formation: an explanation for the antagonistic activity of MyD88s.
Biochem Biophys Res Commun
; 380(1): 183-7, 2009 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19167362
19.
TET2 missense variants in human neoplasia. A proposal of structural and functional classification.
Mol Genet Genomic Med
; 7(7): e00772, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31187595
20.
Non-canonical dimerization of the androgen receptor and other nuclear receptors: implications for human disease.
Endocr Relat Cancer
; 26(8): R479-R497, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31252411