1.
Org Biomol Chem
; 13(16): 4632-6, 2015 Apr 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25783694
RESUMO
We report herein on an accessible protocol for the asymmetric hydroformylation of vinylarenes using formaldehyde as a substitute for syngas. The regioselectivity (branched/linear = up to 96/4) and enantioselectivity (up to 95% ee) can be attributed to the use of chiral Ph-bpe as a ligand.
2.
J Am Chem Soc
; 134(1): 194-6, 2012 Jan 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22129424
RESUMO
N-Sulfonyl-1,2,3-triazoles react with water in the presence of a rhodium catalyst to produce α-amino ketones in high yield. An intermediary α-imino rhodium(II) carbenoid undergoes insertion into the O-H bond of water. This transformation formally achieves 1,2-aminohydroxylation of terminal alkynes in a regioselective fashion when combined with the copper(I)-catalyzed 1,3-dipolar cycloaddition with N-sulfonyl azides.