Detalhe da pesquisa
1.
Phosphodiesterase inhibitors. Part 3: Design, synthesis and structure-activity relationships of dual PDE3/4-inhibitory fused bicyclic heteroaromatic-dihydropyridazinones with anti-inflammatory and bronchodilatory activity.
Bioorg Med Chem
; 20(5): 1644-58, 2012 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22336247
2.
Phosphodiesterase inhibitors. Part 2: design, synthesis, and structure-activity relationships of dual PDE3/4-inhibitory pyrazolo[1,5-a]pyridines with anti-inflammatory and bronchodilatory activity.
Bioorg Med Chem Lett
; 21(18): 5451-6, 2011 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21764304
3.
Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice.
Am J Respir Crit Care Med
; 180(4): 326-38, 2009 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19498055
4.
Discovery of BMS-986235/LAR-1219: A Potent Formyl Peptide Receptor 2 (FPR2) Selective Agonist for the Prevention of Heart Failure.
J Med Chem
; 63(17): 9003-9019, 2020 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32407089
5.
KRP-203, a novel synthetic immunosuppressant, prolongs graft survival and attenuates chronic rejection in rat skin and heart allografts.
Circulation
; 111(2): 222-9, 2005 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-15642767
6.
Design and synthesis of novel 7-heterocycle-6-trifluoromethyl-3-oxoquinoxaline-2-carboxylic acids bearing a substituted phenyl group as superior AMPA receptor antagonists with good physicochemical properties.
Bioorg Med Chem
; 14(3): 776-92, 2006 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16214358
7.
Design, synthesis, and AMPA receptor antagonistic activity of a novel 6-nitro-3-oxoquinoxaline-2-carboxylic acid with a substituted phenyl group at the 7 position.
Bioorg Med Chem
; 13(20): 5841-63, 2005 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15993606