Detalhe da pesquisa
1.
Structure-guided discovery of a novel, potent, and orally bioavailable 3,5-dimethylisoxazole aryl-benzimidazole BET bromodomain inhibitor.
Bioorg Med Chem
; 27(3): 457-469, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30606676
2.
Fully human anti-CD39 antibody potently inhibits ATPase activity in cancer cells via uncompetitive allosteric mechanism.
MAbs
; 12(1): 1838036, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33146056
3.
Discovery of Lanraplenib (GS-9876): A Once-Daily Spleen Tyrosine Kinase Inhibitor for Autoimmune Diseases.
ACS Med Chem Lett
; 11(4): 506-513, 2020 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32292557
4.
Mutations in adenosine deaminase-like (ADAL) protein confer resistance to the antiproliferative agents N6-cyclopropyl-PMEDAP and GS-9219.
Anticancer Res
; 33(5): 1899-912, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23645737
5.
Lipid-sensing high-throughput ApoA-I assays.
J Biomol Screen
; 17(8): 1050-61, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22811478
6.
The HCV non-nucleoside inhibitor Tegobuvir utilizes a novel mechanism of action to inhibit NS5B polymerase function.
PLoS One
; 7(6): e39163, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22720059