1.
J Org Chem
; 85(7): 5109-5113, 2020 Apr 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32138515
RESUMO
The addition of methanesulfonic acid to N-(2,6-dimethylpyridin-4-yl)-N-methyl-2-iso-propylaniline led to the selective protonation of the pyridine nitrogen atom, resulting in a significant deceleration of the rotation rates around both N-pyridyl and N-(i-Pr)phenyl bonds through a relayed brake mechanism.