Detalhe da pesquisa
1.
Binding to the conserved and stably folded guide RNA pseudoknot induces Cas12a conformational changes during ribonucleoprotein assembly.
J Biol Chem
; 299(5): 104700, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37059184
2.
A Protein-Adsorbent Hydrogel with Tunable Stiffness for Tissue Culture Demonstrates Matrix-Dependent Stiffness Responses.
Adv Funct Mater
; 34(17)2024 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38693998
3.
Microprobes for Label-Free Detection of Short Tandem Repeats: An Insight into Alleviating Secondary Structure Effects.
Anal Chem
; 95(36): 13528-13536, 2023 09 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37651633
4.
Global mpox lineage discovery and rapid outbreak tracking with nanopore sequencing.
Virol J
; 20(1): 90, 2023 05 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37149667
5.
Revisiting T7 RNA polymerase transcription in vitro with the Broccoli RNA aptamer as a simplified real-time fluorescent reporter.
J Biol Chem
; 296: 100175, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33303627
6.
Effect of 2'-5'/3'-5' phosphodiester linkage heterogeneity on RNA interference.
Nucleic Acids Res
; 48(9): 4643-4657, 2020 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32282904
7.
Extensive CRISPR RNA modification reveals chemical compatibility and structure-activity relationships for Cas9 biochemical activity.
Nucleic Acids Res
; 47(2): 546-558, 2019 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30517736
8.
Systematic microsatellite repeat expansion cloning and validation.
Hum Genet
; 139(10): 1233-1246, 2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-32277284
9.
Infrared Spectroscopy Reveals the Preferred Motif Size and Local Disorder in Parallel Stranded DNA G-Quadruplexes.
Chembiochem
; 21(19): 2792-2804, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32372560
10.
Novel probes for label-free detection of neurodegenerative GGGGCC repeats associated with amyotrophic lateral sclerosis.
Anal Bioanal Chem
; 411(26): 6995-7003, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31435686
11.
Chimeric Guides Probe and Enhance Cas9 Biochemical Activity.
Biochemistry
; 57(21): 3027-3031, 2018 05 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-29746102
12.
Stable association of RNAi machinery is conserved between the cytoplasm and nucleus of human cells.
RNA
; 22(7): 1085-98, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27198507
13.
Pathogenic C9ORF72 Antisense Repeat RNA Forms a Double Helix with Tandem C:C Mismatches.
Biochemistry
; 55(9): 1283-6, 2016 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26878348
14.
Promoter RNA links transcriptional regulation of inflammatory pathway genes.
Nucleic Acids Res
; 41(22): 10086-109, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23999091
15.
Structurally conserved Nop56/58 N-terminal domain facilitates archaeal box C/D ribonucleoprotein-guided methyltransferase activity.
J Biol Chem
; 287(23): 19418-28, 2012 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22496443
16.
Stepping toward therapeutic CRISPR.
Proc Natl Acad Sci U S A
; 112(51): 15536-7, 2015 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26644585
17.
Modulation of lncRNA links endothelial glycocalyx to vascular dysfunction of tyrosine kinase inhibitor.
Cardiovasc Res
; 119(10): 1997-2013, 2023 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37267414
18.
Parallelized multidimensional analytic framework applied to mammary epithelial cells uncovers regulatory principles in EMT.
Nat Commun
; 14(1): 688, 2023 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36755019
19.
Signature amino acids enable the archaeal L7Ae box C/D RNP core protein to recognize and bind the K-loop RNA motif.
RNA
; 16(1): 79-90, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19926724
20.
Transcriptional regulation by small RNAs at sequences downstream from 3' gene termini.
Nat Chem Biol
; 6(8): 621-9, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20581822