Detalhe da pesquisa
1.
Hearing loss without overt metabolic acidosis in ATP6V1B1 deficient MRL mice, a new genetic model for non-syndromic deafness with enlarged vestibular aqueducts.
Hum Mol Genet
; 26(19): 3722-3735, 2017 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28934385
2.
A hypomorphic mutation of the gamma-1 adaptin gene (Ap1g1) causes inner ear, retina, thyroid, and testes abnormalities in mice.
Mamm Genome
; 27(5-6): 200-12, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27090238
3.
A QTL on Chr 5 modifies hearing loss associated with the fascin-2 variant of DBA/2J mice.
Mamm Genome
; 26(7-8): 338-47, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26092689
4.
Mutations in Grxcr1 are the basis for inner ear dysfunction in the pirouette mouse.
Am J Hum Genet
; 86(2): 148-60, 2010 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-20137774
5.
Behavioral phenotypes revealed during reversal learning are linked with novel genetic loci in diversity outbred mice.
Addict Neurosci
; 42022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36714272
6.
The R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J mice.
J Neurosci
; 30(29): 9683-94, 2010 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-20660251
7.
High-throughput measurement of fibroblast rhythms reveals genetic heritability of circadian phenotypes in diversity outbred mice and their founder strains.
Sci Rep
; 11(1): 2573, 2021 01 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33510298
8.
Characterization of genetically complex Collaborative Cross mouse strains that model divergent locomotor activating and reinforcing properties of cocaine.
Psychopharmacology (Berl)
; 237(4): 979-996, 2020 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-31897574
9.
A locus on distal chromosome 11 (ahl8) and its interaction with Cdh23 ahl underlie the early onset, age-related hearing loss of DBA/2J mice.
Genomics
; 92(4): 219-25, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18662770
10.
Congenital hypothyroidism, dwarfism, and hearing impairment caused by a missense mutation in the mouse dual oxidase 2 gene, Duox2.
Mol Endocrinol
; 21(7): 1593-602, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17440044
11.
Deletion of a Long-Range Dlx5 Enhancer Disrupts Inner Ear Development in Mice.
Genetics
; 208(3): 1165-1179, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29301908
12.
The chloride intracellular channel protein CLIC5 is expressed at high levels in hair cell stereocilia and is essential for normal inner ear function.
J Neurosci
; 26(40): 10188-98, 2006 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-17021174
13.
A missense mutation in the conserved C2B domain of otoferlin causes deafness in a new mouse model of DFNB9.
Hear Res
; 234(1-2): 21-8, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17967520
14.
Effects of Cdh23 single nucleotide substitutions on age-related hearing loss in C57BL/6 and 129S1/Sv mice and comparisons with congenic strains.
Sci Rep
; 7: 44450, 2017 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28287619
15.
Hearing impairment in hypothyroid dwarf mice caused by mutations of the thyroid peroxidase gene.
J Assoc Res Otolaryngol
; 15(1): 45-55, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24297261
16.
CLIC5 stabilizes membrane-actin filament linkages at the base of hair cell stereocilia in a molecular complex with radixin, taperin, and myosin VI.
Cytoskeleton (Hoboken)
; 71(1): 61-78, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24285636
17.
Mutations of the mouse ELMO domain containing 1 gene (Elmod1) link small GTPase signaling to actin cytoskeleton dynamics in hair cell stereocilia.
PLoS One
; 7(4): e36074, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22558334
18.
Association of a citrate synthase missense mutation with age-related hearing loss in A/J mice.
Neurobiol Aging
; 33(8): 1720-9, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21803452
19.
Genetic background effects on age-related hearing loss associated with Cdh23 variants in mice.
Hear Res
; 283(1-2): 80-8, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22138310
20.
A modifier gene alleviates hypothyroidism-induced hearing impairment in Pou1f1dw dwarf mice.
Genetics
; 189(2): 665-73, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21840860