Some biochemical indices of posttransfusion shock induced under protection by selective hypothermia of the brain.

Biochemical disorders accompanying posttransfusion shock in cats under protection by selective cerebral hypothermia, by our own method was studied in cats. In 11 of 22 cats, selective cerebral hypothermia was performed before transfusion of human group A blood. In 11 control cats, transfusions were made without prior selective cerebral hypothermia. The following parameters were determined in venous blood: pH, pCO2, HCO3, content and excess of buffer bases. Selective cerebral hypothermia diminished mortality in cats in posttransfusion shock and reduced the intensity of the biochemical changes accompanying shock.

Prevention of experimental gastric ulcers in rats by dial derivatives.

In 111 rats divided into 5 groups, Ipronal (5-allyl-5-(beta-hydroxypropyl)-barbituric acid) protected rats from development of experimental ulceration of the gastric mucosa twice as effectively as diallylbarbituric acid and compound D2H (5-isopropyl-5-(beta-hydroxypropyl)-barbituric acid). Compound D1S (alpha-allophanyl-alpha-allyl-gamma-valerolactone) was devoid of this action.

[Treatment of acute leukemias in adults. IV. Treatment results on 375 patients at 9 hematology centers]. / Leczenie ostrych bialaczek u doroslych. IV. Wyniki leczenia 375 chorych z 9 osrodków hematologicznych.

On the basis of standardized protocols of the therapeutic results of acute non-lymphoblastic leukaemias in adults sent to the Institute of Haematology in Warsaw from 8 haematological centres in Poland it was demonstrated that complete remission occurred in 34.4% of patients (129 out of 375 cases). The mean survival time of the patients treated intensively according to programmes I, II, III and IV 8.6 months, those of patients with complete remission - 13.5 months, patients without complete remission - 3.7 months. The most frequent cause of death (82.5%) were infections and/or haemarrhagic diathesis.