Detalhe da pesquisa
1.
NRF2 is required for neonatal mouse beta cell growth by maintaining redox balance and promoting mitochondrial biogenesis and function.
Diabetologia
; 67(3): 547-560, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38206362
2.
The many lives of Myc in the pancreatic ß-cell.
J Biol Chem
; 296: 100122, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33239359
3.
Inhibition of Atypical Protein Kinase C Reduces Inflammation-Induced Retinal Vascular Permeability.
Am J Pathol
; 188(10): 2392-2405, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30220554
4.
MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism.
Proc Natl Acad Sci U S A
; 112(21): 6539-44, 2015 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25964345
5.
SIRT3-AMP-Activated Protein Kinase Activation by Nitrite and Metformin Improves Hyperglycemia and Normalizes Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction.
Circulation
; 133(8): 717-31, 2016 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26813102
6.
Transcriptional activation of the Myc gene by glucose in ß-cells requires a ChREBP-dependent 3-D chromatin interaction between the Myc and Pvt1 genes.
Mol Metab
; 79: 101848, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38042369
7.
Time-dependent changes in glucose and insulin regulation during intermittent hypoxia and continuous hypoxia.
Eur J Appl Physiol
; 113(2): 467-78, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22801715
8.
NRF2 Dysregulation in Mice Leads to Inadequate Beta-Cell Mass Expansion during Pregnancy and Gestational Diabetes.
bioRxiv
; 2023 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37693560
9.
Single-nucleus RNA sequencing of human pancreatic islets identifies novel gene sets and distinguishes ß-cell subpopulations with dynamic transcriptome profiles.
Genome Med
; 15(1): 30, 2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37127706
10.
Magnetogenetic cell activation using endogenous ferritin.
bioRxiv
; 2023 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37786709
11.
Human Pancreatic α-Cell Heterogeneity and Trajectory Inference Analysis Using Integrated Single Cell- and Single Nucleus-RNA Sequencing Platforms.
bioRxiv
; 2023 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38014078
12.
Spatiotemporal regulation of GIPR signaling impacts glucose homeostasis as revealed in studies of a common GIPR variant.
Mol Metab
; 78: 101831, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37925022
13.
A novel therapeutic combination of sitagliptin and melatonin regenerates pancreatic ß-cells in mouse and human islets.
Biochim Biophys Acta Mol Cell Res
; 1869(8): 119263, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35364117
14.
Nrf2 Regulates ß-Cell Mass by Suppressing ß-Cell Death and Promoting ß-Cell Proliferation.
Diabetes
; 71(5): 989-1011, 2022 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35192689
15.
Maladaptive positive feedback production of ChREBPß underlies glucotoxic ß-cell failure.
Nat Commun
; 13(1): 4423, 2022 07 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35908073
16.
DYRK1A Inhibitors as Potential Therapeutics for ß-Cell Regeneration for Diabetes.
J Med Chem
; 64(6): 2901-2922, 2021 03 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33682417
17.
Nrf2: The Master and Captain of Beta Cell Fate.
Trends Endocrinol Metab
; 32(1): 7-19, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33243626
18.
Human Beta Cell Regenerative Drug Therapy for Diabetes: Past Achievements and Future Challenges.
Front Endocrinol (Lausanne)
; 12: 671946, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34335466
19.
GLP-1 receptor signaling increases PCSK1 and ß cell features in human α cells.
JCI Insight
; 6(3)2021 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33554958
20.
Molecular control of cell cycle progression in the pancreatic beta-cell.
Endocr Rev
; 27(4): 356-70, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16638909