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1.
Instr Course Lect ; 73: 305-324, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38090906

RESUMO

A comprehensive analysis of the assessment, diagnosis, and management of phalangeal fractures and fingertip injuries should emphasize the importance of achieving the right balance between undertreatment and overtreatment. Phalangeal injuries are complex, requiring an in-depth understanding of hand anatomy, fracture patterns, and treatment options to optimize patient outcomes. A thorough examination of proximal and middle phalangeal fractures and fingertip injuries, including those to the nail bed and distal phalanx, is important. A systematic approach to addressing the most prevalent injuries in this category should be implemented while highlighting the need for patient-specific approaches to treatment and a multidisciplinary perspective to ensure the best possible outcomes for patients.


Assuntos
Traumatismos dos Dedos , Falanges dos Dedos da Mão , Fraturas Ósseas , Humanos , Fraturas Ósseas/diagnóstico por imagem , Fraturas Ósseas/cirurgia , Traumatismos dos Dedos/diagnóstico por imagem , Traumatismos dos Dedos/cirurgia , Fixação Interna de Fraturas , Falanges dos Dedos da Mão/diagnóstico por imagem , Falanges dos Dedos da Mão/lesões
2.
Instr Course Lect ; 73: 285-304, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38090905

RESUMO

Metacarpal fractures are among the most common hand fractures. To properly manage these injuries, surgeons must understand the anatomy, biomechanics, clinical assessment, surgical and nonsurgical treatment options, and potential complications. Metacarpal head fractures often require surgical treatment to restore the joint surface by using a variety of techniques. Metacarpal neck fractures are usually stable injuries that do not require surgical intervention, but surgeons must know when surgical intervention is indicated. Fractures of the metacarpal shaft can be treated surgically and nonsurgically and may be associated with large bone defects or soft-tissue injuries that require careful consideration. Finally, fractures involving the carpometacarpal joints must be promptly managed to avoid long-term complications, potentially requiring salvage procedures.


Assuntos
Fraturas Ósseas , Traumatismos da Mão , Ossos Metacarpais , Humanos , Ossos Metacarpais/lesões , Fraturas Ósseas/cirurgia , Traumatismos da Mão/etiologia , Traumatismos da Mão/cirurgia , Fixação Interna de Fraturas/efeitos adversos , Fixação Interna de Fraturas/métodos
3.
Instr Course Lect ; 73: 325-346, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38090907

RESUMO

Multiple fracture patterns can occur around the proximal interphalangeal joint and require surgeons to have a thorough understanding of the anatomy, clinical and radiographic examination, common fracture patterns, surgical and nonsurgical treatment options, and potential complications. Proximal phalangeal condylar fractures are typically managed surgically, because even nondisplaced fractures have a propensity for displacement. Middle phalangeal base fractures most commonly present as a volar lip fracture with or without dorsal subluxation or dislocation. Treatment options include extension block splinting or pinning, transarticular pinning, open reduction and internal fixation, external fixation, volar plate arthroplasty, and hemihamate arthroplasty. Less common fractures include dorsal lip fractures with or without volar subluxation or dislocation (the central slip fracture), lateral plateau impaction or avulsion injuries, and pilon fractures. The main goals in the management of middle phalangeal base fractures are to restore articular congruency and initial early range of motion, which are more important than obtaining an anatomic reduction.


Assuntos
Fraturas do Tornozelo , Traumatismos dos Dedos , Fraturas Ósseas , Luxações Articulares , Humanos , Articulações dos Dedos/cirurgia , Fraturas Ósseas/diagnóstico por imagem , Fraturas Ósseas/cirurgia , Traumatismos dos Dedos/diagnóstico por imagem , Traumatismos dos Dedos/cirurgia , Luxações Articulares/diagnóstico , Luxações Articulares/cirurgia , Fixação Interna de Fraturas , Amplitude de Movimento Articular
4.
Instr Course Lect ; 73: 497-510, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38090920

RESUMO

Phalangeal fractures are extremely common in the pediatric and adolescent populations. The incidence of phalangeal fractures peaks in children ages 10 to 14 years, corresponding to the age in which children begin contact sports. Younger children are more likely to experience crush injuries, whereas older children often sustain phalangeal fractures during sports. The physis is particularly susceptible to fracture because of the biomechanically weak nature of the physis compared with the surrounding ligaments and bone. Phalangeal fractures are identified through a thorough physical examination and are subsequently confirmed with radiographic evaluation. Management of pediatric phalangeal fractures is dependent on the age of the child, the severity of the injury, and the degree of fracture displacement. Nondisplaced fractures are often managed nonsurgically with immobilization, whereas unstable, displaced fractures may require surgery, which is often a closed rather than open reduction and percutaneous pinning.


Assuntos
Traumatismos dos Dedos , Falanges dos Dedos da Mão , Fixação Intramedular de Fraturas , Fraturas Ósseas , Esportes , Adolescente , Criança , Humanos , Falanges dos Dedos da Mão/diagnóstico por imagem , Falanges dos Dedos da Mão/lesões , Falanges dos Dedos da Mão/cirurgia , Fraturas Ósseas/diagnóstico por imagem , Fraturas Ósseas/cirurgia
5.
J Hand Surg Am ; 2024 May 23.
Artigo em Inglês | MEDLINE | ID: mdl-38795103

RESUMO

Health care systems, including operating rooms, are a considerable contributor to environmental waste. Given ongoing concerns regarding water scarcity in the United States and worldwide, action to reduce water utilization should be taken. Traditional water-based hand scrubbing wastes an estimated 11 L of water per scrub. Waterless hand rubbing with an alcohol-based solution has been shown to be as effective as traditional water-based hand scrubbing in surgical hand antisepsis and in preventing surgical site infections. Furthermore, alcohol-based rubbing results in less waste and reduced costs when compared with water-based hand scrubbing. The hand surgery operating room, including minor procedure rooms, serves as an opportunity to decrease water use and reduce the environmental impact of our field. Waterless alcohol-based hand rubbing for antisepsis may also be an opportunity to save money and provide value-based care to our patients.

6.
J Hand Surg Am ; 48(6): 626.e1-626.e8, 2023 06.
Artigo em Inglês | MEDLINE | ID: mdl-35440404

RESUMO

PURPOSE: This study investigated metacarpal fracture occurrences, characteristics, treatments, and return-to-play times for National Football League (NFL) athletes. METHODS: NFL players who sustained metacarpal fractures during the 2012 to 2018 seasons were reviewed. All players on the 32 NFL team active rosters with metacarpal fractures recorded through the NFL Injury Database were included. Player age, time in the league, player position, injury setting, injury mechanism, fractured ray, management, and return-to-play were recorded. RESULTS: There were 208 injury occurrences resulting in 1 or more metacarpal fractures, identified in 205 players. Of these, 81 (39%) injuries were operated. Return-to-play data were available for 173 (83%) injured players. The median return-to-play time for all athletes was 15 days (interquartile range, 1-55 days). Of the injured players, 130 (71%) missed time but returned the same season. Within this 130-player subset, 69 (53%) were treated nonsurgically and 61 (47%) operatively with median return-to-play times of 16 days (interquartile range, 6-30 days) and 20 days (interquartile range, 16-42 days) respectively. Eighteen individuals in this 130-player subgroup sustained a thumb metacarpal fracture. The return-to-play time was slower for patients sustaining thumb metacarpal fractures compared to other metacarpal fractures, and was significantly longer (median, 55 days) following nonsurgical treatment of thumb fractures compared with operative intervention (median, 24 days). A regression analysis revealed no trend or difference in return to football with respect to player age, time in the league, injury setting (practice vs game), injury mechanism, articular involvement, multiple concomitant injuries, or player position. CONCLUSIONS: Most NFL players who sustain metacarpal fractures miss less than 3 weeks and return to play the same season. The only variables that lessen the return-to-play time are involvement of lesser digit metacarpals and operative intervention for treatment of thumb metacarpal fractures. TYPE OF STUDY/LEVEL OF EVIDENCE: Prognostic IV.


Assuntos
Traumatismos dos Dedos , Futebol Americano , Fraturas Ósseas , Traumatismos da Mão , Ossos Metacarpais , Humanos , Futebol Americano/lesões , Volta ao Esporte , Ossos Metacarpais/lesões , Fraturas Ósseas/etiologia , Fraturas Ósseas/cirurgia , Traumatismos da Mão/epidemiologia , Traumatismos da Mão/etiologia , Traumatismos da Mão/cirurgia
7.
J Hand Surg Am ; 48(6): 612-618, 2023 06.
Artigo em Inglês | MEDLINE | ID: mdl-36894370

RESUMO

Conventional teaching in the management of partial hand amputations prioritizes residual limb length, often through local, regional, or distant flaps. While multiple options exist to provide durable soft tissue coverage, only a few flaps are thin and pliable enough to match that of the dorsal hand skin. Despite debulking, excessive soft tissues from previous flap reconstructions can interfere with residual limb function, prosthesis fit, and surface electrode recording for myoelectric prostheses. With rapid advances in prosthetic technology and nerve transfer techniques, patients can achieve very high levels of function following prosthetic rehabilitation that rival, or even outpace, traditional soft tissue reconstruction. Therefore, our reconstruction algorithm for partial hand amputations has evolved to the thinnest coverage possible, providing adequate durability. This evolution has provided our patients with faster and more secure prosthesis fitting with better surface electrode detection, enabling earlier and improved use of simple and advanced partial hand prostheses.


Assuntos
Membros Artificiais , Retalhos Cirúrgicos , Humanos , Amputação Cirúrgica , Mãos/cirurgia
8.
N Engl J Med ; 380(21): 2031-2040, 2019 05 23.
Artigo em Inglês | MEDLINE | ID: mdl-31116919

RESUMO

BACKGROUND: Nasal high-flow therapy is an alternative to nasal continuous positive airway pressure (CPAP) as a means of respiratory support for newborn infants. The efficacy of high-flow therapy in nontertiary special care nurseries is unknown. METHODS: We performed a multicenter, randomized, noninferiority trial involving newborn infants (<24 hours of age; gestational age, ≥31 weeks) in special care nurseries in Australia. Newborn infants with respiratory distress and a birth weight of at least 1200 g were assigned to treatment with either high-flow therapy or CPAP. The primary outcome was treatment failure within 72 hours after randomization. Infants in whom high-flow therapy failed could receive CPAP. Noninferiority was determined by calculating the absolute difference in the risk of the primary outcome, with a noninferiority margin of 10 percentage points. RESULTS: A total of 754 infants (mean gestational age, 36.9 weeks, and mean birth weight, 2909 g) were included in the primary intention-to-treat analysis. Treatment failure occurred in 78 of 381 infants (20.5%) in the high-flow group and in 38 of 373 infants (10.2%) in the CPAP group (risk difference, 10.3 percentage points; 95% confidence interval [CI], 5.2 to 15.4). In a secondary per-protocol analysis, treatment failure occurred in 49 of 339 infants (14.5%) in the high-flow group and in 27 of 338 infants (8.0%) in the CPAP group (risk difference, 6.5 percentage points; 95% CI, 1.7 to 11.2). The incidences of mechanical ventilation, transfer to a tertiary neonatal intensive care unit, and adverse events did not differ significantly between the groups. CONCLUSIONS: Nasal high-flow therapy was not shown to be noninferior to CPAP and resulted in a significantly higher incidence of treatment failure than CPAP when used in nontertiary special care nurseries as early respiratory support for newborn infants with respiratory distress. (Funded by the Australian National Health and Medical Research Council and Monash University; HUNTER Australian and New Zealand Clinical Trials Registry number, ACTRN12614001203640.).


Assuntos
Pressão Positiva Contínua nas Vias Aéreas , Ventilação não Invasiva , Oxigenoterapia/métodos , Síndrome do Desconforto Respiratório do Recém-Nascido/terapia , Pressão Positiva Contínua nas Vias Aéreas/efeitos adversos , Feminino , Humanos , Recém-Nascido , Unidades de Terapia Intensiva Neonatal , Masculino , Ventilação não Invasiva/efeitos adversos , Falha de Tratamento
9.
Oecologia ; 199(3): 649-659, 2022 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-35833986

RESUMO

We sought to understand the role that water availability (expressed as an aridity index) plays in determining regional and global patterns of richness and evenness, and in turn how these water availability-diversity relationships may result in different richness-evenness relationships at regional and global scales. We examined relationships between water availability, richness and evenness for eight grassy biomes spanning broad water availability gradients on five continents. Our study found that relationships between richness and water availability switched from positive for drier (South Africa, Tibet and USA) vs. negative for wetter (India) biomes, though were not significant for the remaining biomes. In contrast, only the India biome showed a significant relationship between water availability and evenness, which was negative. Globally, the richness-water availability relationship was hump-shaped, however, not significant for evenness. At the regional scale, a positive richness-evenness relationship was found for grassy biomes in India and Inner Mongolia, China. In contrast, this relationship was weakly concave-up globally. These results suggest that different, independent factors are determining patterns of species richness and evenness in grassy biomes, resulting in differing richness-evenness relationships at regional and global scales. As a consequence, richness and evenness may respond very differently across spatial gradients to anthropogenic changes, such as climate change.


Assuntos
Biodiversidade , Poaceae , China , Ecossistema , Água
10.
Med Educ ; 56(2): 159-169, 2022 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-34383965

RESUMO

OBJECTIVE: The participation of students from both undergraduate medical education (UGME) and postgraduate medical education (PGME) in independent patient care contributes to the development of knowledge, skills and the professional identity of students. A continuing collaboration between students and their preceptor might contribute to opportunities for students to independently provide patient care. In this systematic review, we aim to evaluate whether longitudinal training models facilitate the independent practice of students and what characteristics of longitudinal training models contribute to this process. METHOD: This systematic review was performed according to the PRISMA guidelines. In May 2020, we performed a search in three databases. Articles evaluating the impact of longitudinal training models on the independent practice of students from both UGME and PGME programmes were eligible for the study. A total of 68 articles were included in the study. Quality of the included studies was assessed using the Quality Assessment Tool for Studies with Diverse Designs (QATSDD). RESULTS: Both UGME and PGME students in longitudinal training models are more frequently allowed to provide patient care independently when compared with their block model peers, and they also feel better prepared for independent practice at the end of their training programme. Several factors related to longitudinal training models stimulate opportunities for students to work independently. The most important factors in this process are the longitudinal relationships with preceptors and with the health care team. CONCLUSION: Due to the ongoing collaboration between students and their preceptor, they develop an intensive and supportive mutual relationship, allowing for the development of a safe learning environment. As a result, the professional development of students is fostered, and students gradually become part of the health care team, allowing them the opportunity to engage in independent patient care.


Assuntos
Educação de Graduação em Medicina , Educação Médica , Humanos , Aprendizagem , Assistência ao Paciente , Estudantes
11.
J Hand Surg Am ; 47(2): 145-150, 2022 02.
Artigo em Inglês | MEDLINE | ID: mdl-34702630

RESUMO

PURPOSE: The ideal method of central slip reconstruction is difficult to determine due to the multitude of techniques, nonstandardized outcome reporting, and small patient series in the literature. Although most boutonniere deformities may be treated with nonsurgical measures, chronic, subacute, or open injuries may require operative intervention. To aid surgeons in the choice of the ideal central slip reconstruction method, this biomechanical study compared the 3 most common methods performed at our institution: direct repair, lateral band centralization, and distally-based flexor digitorum superficialis (FDS) slip repair. METHODS: A boutonniere deformity was induced in 35 fresh-frozen cadaver digits. The central slip was repaired in 9 digits using a primary suture repair, in 9 digits using a lateral band centralization technique, and in 9 digits using a distally-based FDS slip reconstruction. A control group without injury was tested in 8 digits. Following repair or reconstruction, each digit was tested for load to failure, strain, and stiffness at the repair. RESULTS: The average load to failure after central slip reconstruction was significantly greater for a distally based FDS slip method at 82.1 ± 14.6 N (95% CI, 62.2-101.9 N) than all other repair types. Although the FDS slip reconstruction was not as strong as the intact state (82.1 N vs 156.2 N, respectively), it was 2.6 times stronger than the lateral band centralization (82.1 N vs 31.6 N, respectively) and 3 times stronger than a primary repair (82.1 N vs 27.6 N, respectively). CONCLUSIONS: Reconstruction of the central slip using a distally-based FDS slip provided the greatest biomechanical strength compared with the direct repair or lateral band centralization. CLINICAL RELEVANCE: The use of a distally based reconstruction using FDS may allow for safer early motion.


Assuntos
Deformidades Adquiridas da Mão , Fenômenos Biomecânicos , Cadáver , Deformidades Adquiridas da Mão/cirurgia , Humanos , Suturas
12.
J Pediatr ; 227: 135-141.e1, 2020 12.
Artigo em Inglês | MEDLINE | ID: mdl-32679201

RESUMO

OBJECTIVE: To evaluate demographic and clinical variables as predictors of nasal high-flow treatment success in newborn infants with respiratory distress cared for in Australian nontertiary special care nurseries. STUDY DESIGN: A secondary analysis of the HUNTER trial, a multicenter, randomized controlled trial evaluating nasal high-flow as primary respiratory support for newborn infants with respiratory distress who were born ≥31 weeks of gestation and with birth weight ≥1200 g, and cared for in Australian nontertiary special care nurseries. Treatment success within 72 hours after randomization to nasal high-flow was determined using objective criteria. Univariable screening and multivariable analysis was used to determine predictors of nasal high-flow treatment success. RESULTS: Infants (n = 363) randomized to nasal high-flow in HUNTER were included in the analysis; the mean gestational age was 36.9 ± 2.7 weeks and birth weight 2928 ± 782 g. Of these infants, 290 (80%) experienced nasal high-flow treatment success. On multivariable analysis, nasal high-flow treatment success was predicted by higher gestational age and lower fraction of inspired oxygen immediately before randomization, but not strongly. The final model was found to have an area under the curve of 0.65, which after adjustment for optimism was found to be 0.63 (95% CI, 0.57-0.70). CONCLUSIONS: Gestational age and supplemental oxygen requirement may be used to guide decisions regarding the most appropriate initial respiratory support for newborn infants in nontertiary special care nurseries. Further prospective research is required to better identify which infants are most likely to be successfully treated with nasal high-flow. TRIAL REGISTRATION: ACTRN12614001203640.


Assuntos
Ventilação não Invasiva/métodos , Oxigenoterapia/métodos , Síndrome do Desconforto Respiratório do Recém-Nascido/terapia , Austrália , Cânula , Feminino , Humanos , Recém-Nascido , Recém-Nascido Prematuro , Recém-Nascido de muito Baixo Peso , Masculino
13.
J Hand Surg Am ; 45(5): 444-448, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-31928797

RESUMO

Health care is an important contributor to environmental waste. In 2013, the health care sector was responsible for substantial fractions of national air pollution emissions and impacts, including acid rain (12%), greenhouse gas emissions (10%), smog formation (10%), air pollutants (9%), stratospheric ozone depletion (1%), and carcinogenic and noncarcinogenic air toxins (1% to 2%). Operating rooms produce between 20% and 70% of total hospital waste. Hand surgery, with short, high-volume cases, is a notable contributor to this environmental and subsequent financial burden. This article aims to highlight the Lean and Green initiative proposed by the American Association for Hand Surgery along with the American Society for Surgery of the Hand, the American Society for Peripheral Nerve Surgery, and the American Society of Reconstructive Microsurgery in 2015, to reduce the amount of waste generated by hand surgery. We have reviewed the literature to propose multiple ways to reduce both material and nonmaterial waste-energy consumption, sterilization techniques, reprocessing of devices, patient transportation, production of surgical supply, anesthesia, and sanitation in hand surgery.


Assuntos
Poluentes Atmosféricos , Mãos , Poluentes Atmosféricos/análise , Mãos/cirurgia , Humanos , Salas Cirúrgicas , Estados Unidos
14.
J Hand Surg Am ; 45(12): 1183.e1-1183.e7, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-32723570

RESUMO

PURPOSE: Multiple techniques are described for repair of zone I flexor tendon injuries, many of which are fraught with complications. This study evaluated the clinical complications after a transosseous repair technique. METHODS: A retrospective review of a single institutional database identified all zone I flexor digitorum profundus (FDP) injuries repaired using a transosseous technique. In this technique, 2 nonabsorbable sutures were passed from volar to dorsal through transosseous tunnels and tied dorsally over the distal phalanx proximal to the germinal matrix. Demographics, injury characteristics, operative details, and complications were reviewed. RESULTS: Eight patients met the inclusion criteria. Average age was 31 years (range, 15-66 years) and all patients were male. Eight fingers were included: ring (4), small (3), and middle (1). Seven injuries were closed and one was open. Average time between injury and surgery was 13 days (range, 4-34 days). Five patients experienced complications, including osteomyelitis, chronic draining granuloma, and abnormal nail growth. Three patients required an additional operative procedure for management of complications. CONCLUSIONS: Transosseous repair of zone I flexor digitorum profundus injuries with a buried dorsal suture is associated with a high rate of clinical complications. TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic V.


Assuntos
Traumatismos dos Dedos , Falanges dos Dedos da Mão , Traumatismos dos Tendões , Adulto , Traumatismos dos Dedos/cirurgia , Falanges dos Dedos da Mão/cirurgia , Humanos , Masculino , Estudos Retrospectivos , Técnicas de Sutura , Traumatismos dos Tendões/cirurgia , Tendões
15.
J Hand Surg Am ; 44(6): 520.e1-520.e9, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-30344022

RESUMO

PURPOSE: Nitinol memory compression staples are a recent addition to carpal bone fixation. Compared with traditional staples, they have been shown to have superior compression at the far cortex relative to standard and traditional compression staples. The purpose of this study was to (1) determine the effective leg length of different nitinol staples, (2) confirm the effect of 1 versus 2 staples on biomechanical compression, and (3) determine the effect of troughing (countersinking the staple into bone) the bone on staple biomechanical properties. METHODS: Three commonly used nitinol staples of various bridge and leg lengths were used in a bicortical sawbones block construct. There were 3 separate constructs tested, which included single staple, double staple, and troughed. We measured compression force, stiffness, and bending strength for each construct before and after cyclical 4-point bending. Compression mapping was used to determine the effective leg length of each staple, which included the distance that compression extended beyond the tips of the staple legs. RESULTS: Effective leg length for each staple construct extended 2 mm distal to the tip of the shortest staple leg. Two staple constructs more than doubled compressive force and increased bending strength by greater than 90% in all staple types. There was no loss of compressive force before or after loading for single, double, or troughed constructs with any staple type. CONCLUSIONS: This study supports that nitinol staples do not have to be placed bicortically to achieve adequate compression; placing staples 2 mm short of the far cortex has the same compression as bicortical placement; and troughing of the bone will not significantly diminish the biomechanical properties of the construct. CLINICAL RELEVANCE: Better understanding of the effective leg length of nitinol staples provides support that bicortical placement is not necessary for adequate compression. This study supports troughing bone to minimize implant prominence.


Assuntos
Teste de Materiais , Grampeamento Cirúrgico , Suturas , Ligas , Fenômenos Biomecânicos , Desenho de Equipamento , Humanos , Modelos Anatômicos
16.
J Hand Surg Am ; 44(6): 525.e1-525.e8, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-30733097

RESUMO

Targeted muscle reinnervation (TMR) is a surgical technique that improves modern myoelectric prosthesis functionality and plays an important role in the prevention and treatment of painful postamputation neuromas. Originally described for transhumeral amputations and shoulder disarticulations, the technique is being adapted for treatment of transtibial, transfemoral, transradial, and partial hand amputees. We describe a new technique for forearm TMR following transradial amputation with an emphasis on selecting nerve transfer patterns, managing sensory nerves, improving terminal soft tissue coverage, and employing pattern recognition technology.


Assuntos
Amputados , Músculo Esquelético/inervação , Transferência de Nervo , Rádio (Anatomia)/cirurgia , Amputação Cirúrgica , Membros Artificiais , Feminino , Humanos , Pessoa de Meia-Idade , Neuroma/cirurgia , Neoplasias do Sistema Nervoso Periférico/cirurgia , Complicações Pós-Operatórias
17.
J Hand Surg Am ; 44(2): 163.e1-163.e5, 2019 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-29908928

RESUMO

Control of independent digital flexion and extension has remained an elusive goal in myoelectric prosthetics for upper extremity amputees. We first performed a cadaver study to determine the feasibility of transferring the interossei muscles for each digit to the dorsum of the hand without damaging the neurovascular pedicles. Once this capability was ensured, a clinical case was performed transferring the interossei of the middle and ring fingers to the dorsum of the hand where they could serve as a myoelectric signal for a partial hand amputee to allow individual digital control with a myoelectric prosthesis. Before surgery, it was impossible to detect an independent signal for each interossei; however, after the surgery, signals were reliably detected, which allowed these muscles to serve as myosites for finger flexion using a myoelectric prosthesis and move each digit independently. This concept of salvaging innervated and perfused muscles from an amputated part and transferring them into the more proximal and superficial portion of a salvaged limb has broad applications for improved myoelectric prosthetic control.


Assuntos
Membros Artificiais , Eletromiografia , Dedos/inervação , Músculo Esquelético/inervação , Músculo Esquelético/cirurgia , Adaptação Fisiológica , Adulto , Amputação Traumática/cirurgia , Amputados/reabilitação , Avulsões Cutâneas/cirurgia , Traumatismos dos Dedos/cirurgia , Humanos , Masculino , Desenho de Prótese , Escala Visual Analógica
18.
J Environ Manage ; 235: 42-50, 2019 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-30669092

RESUMO

Ecological modeling that includes plant population processes as a critical determinant of vegetation dynamics is useful for sustainable rangeland management. However, we know little about how long-term sheep grazing pressure drives the plant community structure through changes in different native grass species at both individual and population levels. In this study, we hypothesized that plant populations perform differently under different grazing management due to their specified preference by livestock animals. We also tested whether grazing-rest management, aimed at increasing long-term rangeland sustainability, improves the plant growth of forage grass species. We evaluated plant density, individual morphology and plant-size distribution of dominant grass populations in permanent exclosures and open fields under moderate and intensive grazing pressures in Patagonian steppes (South America). We also examined the effects of seasonal grazing-rest managements on the growth and tillering (asexual reproduction) of forage species plants, using temporary mobile exclosures. Grazing intensity changed population density and structure according to species. Compared to permanent exclosures, moderate grazing maintained the plant density of palatable species highly preferred by sheep, reduced the standing-dead biomass proportion of individual plants, and promoted the green biomass of tussocks. Conversely, intensive grazing (double stocking rates) decreased the plant density and individual size of species highly preferred by sheep, and increased the plant density of non-preferred species. Grazing-rest enhanced forage grass species growth and reproduction compared with year-round grazing management, especially during the growing season of a wet year. Our studies support that sheep can be managed to control the plant-size distribution of dominant grass species, their population dynamics, and thereby the overall forage availability at the community level. Both moderate grazing and grazing-rest management can improve the forage availability and preserve the dominant native grasses. We suggest applying a plant population dynamics perspective to facilitate sustainable management of global rangelands.


Assuntos
Plantas , Poaceae , Animais , Ecologia , Ecossistema , Estações do Ano , Ovinos , América do Sul
19.
Br Med Bull ; 125(1): 5-14, 2018 03 01.
Artigo em Inglês | MEDLINE | ID: mdl-29228112

RESUMO

Introduction: There is a continuing worldwide shortage of organs from deceased human donors for transplantation into patients with end-stage organ failure. Genetically engineered pigs could resolve this problem, and could also provide tissues and cells for the treatment of conditions such as diabetes, Parkinson's disease and corneal blindness. Sources of data: The current literature has been reviewed. Areas of agreement: The pathobiologic barriers are now largely defined. Research progress has advanced through the increasing availability of genetically engineered pigs and novel immunosuppressive agents. Life-supporting pig kidneys and islets have functioned for months or years in nonhuman primates. Areas of controversy: The potential risk of transfer of a pig infectious microorganism to the recipient continues to be debated. Growing points: Increased attention is being paid to selection of patients for initial clinical trials. Areas timely for developing research: Most of the advances required to justify a clinical trial have now been met.


Assuntos
Xenoenxertos , Coleta de Tecidos e Órgãos/métodos , Transplante Heterólogo , Animais , Animais Geneticamente Modificados , Sobrevivência de Enxerto , Humanos , Suínos , Transplante Heterólogo/efeitos adversos , Transplante Heterólogo/métodos
20.
World J Urol ; 36(2): 171-175, 2018 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-29124346

RESUMO

PURPOSE: Live surgery (LS) is considered a useful teaching opportunity. The benefits must be balanced with patient safety concerns. To evaluate the rate of complications of a series of urologic LS performed by experts during the Congress Challenge in Laparoscopy and Robotics (CILR). METHODS: We present a large, multi-institution, multi-surgeon database that derives from 12 CILR events, from 2004 to 2015 with a total of 224 cases. Radical prostatectomy (RP) was the most common procedure and a selection of complex cases was noted. The primary measure was postoperative complications and use of a Postoperative Morbidity Index (PMI) to allow quantitative weighing of postoperative complications. RESULTS: From 12 events, the number of cases increased from 11 in 2004 to 27 in 2015 and a total of 27 surgeons. Of 224 cases (164 laparoscopic and 60 robotic), there were 26 (11.6%) complications: 5 grade I, 5 grade II, 3 grade IIIa, 12 grade IIIb and 1 grade V, the latter from laparoscopic cystectomy. Analysis of PMI was 23 times higher from cystectomy compared to RP. CONCLUSIONS: In the setting of live surgery, the overall rate of complications is low considering the complexity of surgeries. The PMI is not higher in more complex procedures, whereas RP seems very safe.


Assuntos
Laparoscopia/educação , Complicações Pós-Operatórias/epidemiologia , Procedimentos Cirúrgicos Robóticos/educação , Procedimentos Cirúrgicos Urológicos/educação , Estudos de Coortes , Cistectomia/educação , Feminino , Humanos , Excisão de Linfonodo/educação , Masculino , Nefrectomia/educação , Prostatectomia/educação , Estudos Retrospectivos , Índice de Gravidade de Doença
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