Strengthening Bioinformatics and Genomics Analyses Skills in Africa for Attainment of the Sustainable Development Goals: Report of the 2nd Conference of the Nigerian Bioinformatics and Genomics Network.

The second conference of the Nigerian Bioinformatics and Genomics Network (NBGN21) was held from October 11 to October 13, 2021. The event was organized by the Nigerian Bioinformatics and Genomics Network. A 1-day genomic analysis workshop on genome-wide association study and polygenic risk score analysis was organized as part of the conference. It was organized primarily as a research capacity building initiative to empower Nigerian researchers to take a leading role in this cutting-edge field of genomic data science. The theme of the conference was "Leveraging Bioinformatics and Genomics for the attainments of the Sustainable Development Goals." The conference used a hybrid approach-virtual and in-person. It served as a platform to bring together 235 registered participants mainly from Nigeria and virtually, from all over the world. NBGN21 had four keynote speakers and four leading Nigerian scientists received awards for their contributions to genomics and bioinformatics development in Nigeria. A total of 100 travel fellowships were awarded to delegates within Nigeria. A major topic of discussion was the application of bioinformatics and genomics in the achievement of the Sustainable Development Goals (SDG3-Good Health and Well-Being, SDG4-Quality Education, and SDG 15-Life on Land [Biodiversity]). In closing, most of the NBGN21 conference participants were interviewed and interestingly they agreed that bioinformatics and genomic analysis of African genomes are vital in identifying population-specific genetic variants that confer susceptibility to different diseases that are endemic in Africa. The knowledge of this can empower African healthcare systems and governments for timely intervention, thereby enhancing good health and well-being.

Global stability analysis of hepatitis B virus dynamics.

This paper considers the impact of an acute individual's spontaneous clearance, recovery of a chronic individual with full immunity, and risk factor reduction on a hepatitis B virus (HBV) model. The existence and the positivity solution of the model are established. The model threshold quantity is defined and sensitivity analysis is analyzed to demonstrate the effect of various parameters on the spread of the virus. The global stability analysis of the equilibrium is shown using Lyapunov and comparison theorem methods. Finally, computational simulation is presented to validate the analytical solution. The results show that treatment, spontaneous clearance and reduction of the risk factor are highly successful in transmitting and regulating HBV transmission. The effective measure of these parameters as substantiated by our simulations, providing an excellent control method of the transmissible infection of HBV.

The impact of testing and treatment on the dynamics of Hepatitis B virus.

Despite the intervention of WHO on vaccination for reducing the spread of Hepatitis B Virus (HBV), there are records of the high prevalence of HBV in some regions. In this paper, a mathematical model was formulated to analyze the acquisition and transmission process of the virus with the view of identifying the possible way of reducing the menace and mitigating the risk of the virus. The models' positivity and boundedness were demonstrated using well-known theorems. Equating the differential equations to zero demonstrates the equilibria of the solutions i.e., the disease-free and endemic equilibrium. The next Generation Matrix method was used to compute the basic reproduction number for the models. Local and global stabilities of the models were shown via linearization and Lyapunov function methods respectively. The importance of testing and treatment on the dynamics of HBV were fully discussed in this paper. It was discovered that testing at the acute stage of the virus and chronic unaware state helps in better management of the virus.

Evaluation of the scholastic performance of students in 12 programs from a private university in the south-west geopolitical zone in Nigeria.

Cumulative grade point average (CGPA) is a system for calculation of GPA scores and is one way to determine a student's academic performance in a university setting. In Nigeria, an employer evaluates a student's academic performance using their CGPA score. For this study, data were collected from a student database of a private school in the south-west geopolitical zone in Nigeria. Regression analysis, correlation analysis, and analysis of variance (F-test) were employed to determine the study year that students perform better based on CGPA. According to the results, it was observed that students perform much better in year three (300 Level) and year four (400 Level) compared to other levels. In conclusion, we strongly recommend the private university to introduce program that will improve the academic performance of students from year one (100 level).

Data on expenditure, revenue, and economic growth in Nigeria.

This article describes the data for examining the influence of government expenditure and revenue on Nigerian economic growth. Data were extracted from the World Bank database and Central Bank of Nigeria (CBN) Statistical bulletin. The data are available with this article. The data is related to the research article "Newly proposed estimator for ridge parameter: an application to the Nigerian economy" (Lukman and Arowolo, 2018) but not discussed in detail. This data article will assist economists in identifying factors that will affect the economy of a country, especially in the African region.