Detalhe da pesquisa
1.
Kinase domain autophosphorylation rewires the activity and substrate specificity of CK1 enzymes.
Mol Cell
; 82(11): 2006-2020.e8, 2022 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35353987
2.
Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation.
EMBO J
; 41(8): e108443, 2022 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35112738
3.
p63 uses a switch-like mechanism to set the threshold for induction of apoptosis.
Nat Chem Biol
; 16(10): 1078-1086, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32719556
4.
DNA Damaged Induced Cell Death in Oocytes.
Molecules
; 25(23)2020 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33287328
5.
Control mechanisms in germ cells mediated by p53 family proteins.
J Cell Sci
; 2017 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28794013
6.
Fuzzy interactions between the auto-phosphorylated C-terminus and the kinase domain of CK1δ inhibits activation of TAp63α.
Sci Rep
; 13(1): 16423, 2023 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37777570
7.
Deconstructing Protein Binding of Sulfonamides and Sulfonamide Analogues.
JACS Au
; 3(9): 2478-2486, 2023 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37772190
8.
DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma.
Cell Death Dis
; 14(10): 674, 2023 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37828008
9.
Designed Ankyrin Repeat Proteins as a tool box for analyzing p63.
Cell Death Differ
; 29(12): 2445-2458, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35717504
10.
Design, Synthesis, and Evaluation of WD-Repeat-Containing Protein 5 (WDR5) Degraders.
J Med Chem
; 64(15): 10682-10710, 2021 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33980013
11.
Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms.
Cell Chem Biol
; 27(11): 1441-1451.e7, 2020 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32726587
12.
Towards complete polypeptide backbone NH assignment via combinatorial labeling.
J Magn Reson
; 302: 50-63, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30959416
13.
TA*p63 and GTAp63 achieve tighter transcriptional regulation in quality control by converting an inhibitory element into an additional transactivation domain.
Cell Death Dis
; 10(10): 686, 2019 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31527723
14.
Deletions and loss-of-function variants in TP63 associated with orofacial clefting.
Eur J Hum Genet
; 27(7): 1101-1112, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30850703
15.
Non-oncogenic roles of TAp73: from multiciliogenesis to metabolism.
Cell Death Differ
; 25(1): 144-153, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29077094
16.
Regulation of the Activity in the p53 Family Depends on the Organization of the Transactivation Domain.
Structure
; 26(8): 1091-1100.e4, 2018 08 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30099987
17.
Quality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level.
Elife
; 52016 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27021569
18.
Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerization.
Cell Death Differ
; 23(12): 1930-1940, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27716744