Prosthodontic rehabilitation of a patient with nintedanib-induced osteonecrosis of the jaw: A clinical report.

Medication-related osteonecrosis of the jaw results in extensive excision and proves challenging to rehabilitate prosthetically. This article describes the prosthodontic rehabilitation of medication-related osteonecrosis of the jaw induced by nintedanib. A custom-made subperiosteal implant was designed to adapt to the bone, remaining after the excision of the jaw necrosis. The implant followed the anatomic contour of the residual bone and was milled in titanium alloy, allowing the rehabilitation of a patient with a fixed dental prosthesis.