Detalhe da pesquisa
1.
PET Oncological Radiopharmaceuticals: Current Status and Perspectives.
Molecules
; 27(20)2022 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36296381
2.
Ca2+ Binding/Permeation via Calcium Channel, CaV1.1, Regulates the Intracellular Distribution of the Fatty Acid Transport Protein, CD36, and Fatty Acid Metabolism.
J Biol Chem
; 290(39): 23751-65, 2015 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26245899
3.
Ligands for FKBP12 increase Ca2+ influx and protein synthesis to improve skeletal muscle function.
J Biol Chem
; 289(37): 25556-70, 2014 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25053409
4.
Feasibility of [18F]FSPG PET for Early Response Assessment to Combined Blockade of EGFR and Glutamine Metabolism in Wild-Type KRAS Colorectal Cancer.
Tomography
; 9(2): 497-508, 2023 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36961000
5.
Alpha Particle-Emitting Radiopharmaceuticals as Cancer Therapy: Biological Basis, Current Status, and Future Outlook for Therapeutics Discovery.
Mol Imaging Biol
; 25(6): 991-1019, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37845582
6.
Comparative Pharmacology of a Bis-Pivaloyloxymethyl Phosphonate Prodrug Inhibitor of Enolase after Oral and Parenteral Administration.
ACS Pharmacol Transl Sci
; 6(2): 245-252, 2023 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36798479
7.
Anaplerotic nutrient stress drives synergy of angiogenesis inhibitors with therapeutics targeting tumor metabolism.
bioRxiv
; 2023 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37214825
8.
Prodrugs of a 1-Hydroxy-2-oxopiperidin-3-yl Phosphonate Enolase Inhibitor for the Treatment of ENO1-Deleted Cancers.
J Med Chem
; 65(20): 13813-13832, 2022 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36251833
9.
Impaired anaplerosis is a major contributor to glycolysis inhibitor toxicity in glioma.
Cancer Metab
; 9(1): 27, 2021 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34172075
10.
Pharmacokinetics of Orally Administered GS-441524 in Dogs.
bioRxiv
; 2021 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34100016
11.
Homozygous MTAP deletion in primary human glioblastoma is not associated with elevation of methylthioadenosine.
Nat Commun
; 12(1): 4228, 2021 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34244484
12.
Bioreducible Phosphonoamidate Pro-drug Inhibitor of Enolase: Proof of Concept Study.
ACS Med Chem Lett
; 11(7): 1484-1489, 2020 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32676158
13.
An enolase inhibitor for the targeted treatment of ENO1-deleted cancers.
Nat Metab
; 2(12): 1413-1426, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33230295
14.
Adaptive thermogenesis enhances the life-threatening response to heat in mice with an Ryr1 mutation.
Nat Commun
; 11(1): 5099, 2020 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33037202
15.
A chemical chaperone improves muscle function in mice with a RyR1 mutation.
Nat Commun
; 8: 14659, 2017 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28337975
16.
ENOblock Does Not Inhibit the Activity of the Glycolytic Enzyme Enolase.
PLoS One
; 11(12): e0168739, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-28030597
17.
Author Correction: An enolase inhibitor for the targeted treatment of ENO1-deleted cancers.
Nat Metab
; 3(1): 122, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-33340032
18.
Ca(2+) permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function.
Skelet Muscle
; 5: 4, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25717360
19.
AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation.
Nat Med
; 18(2): 244-51, 2012 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22231556
20.
Ryanodine receptors: structure, expression, molecular details, and function in calcium release.
Cold Spring Harb Perspect Biol
; 2(11): a003996, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20961976