Detalhe da pesquisa
1.
Messenger RNA rescues medium-chain acyl-CoA dehydrogenase deficiency in fibroblasts from patients and a murine model.
Hum Mol Genet
; 32(14): 2347-2356, 2023 07 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37162351
2.
Impact of stereopure chimeric backbone chemistries on the potency and durability of gene silencing by RNA interference.
Nucleic Acids Res
; 51(9): 4126-4147, 2023 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37070173
3.
Synthetic mRNA rescues very long-chain acyl-CoA dehydrogenase deficiency in patient fibroblasts and a murine model.
Mol Genet Metab
; 138(1): 106982, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36580829
4.
Amnio acid substitution at position 298 of human glucose-6 phosphatase-α significantly impacts its stability in mammalian cells.
Amino Acids
; 55(5): 695-708, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-36944899
5.
Aptamers: Cutting edge of cancer therapies.
Mol Ther
; 29(8): 2396-2411, 2021 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34146729
6.
Synthetic human ABCB4 mRNA therapy rescues severe liver disease phenotype in a BALB/c.Abcb4-/- mouse model of PFIC3.
J Hepatol
; 74(6): 1416-1428, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33340584
7.
Toward the full potential of mRNA therapeutics.
Mol Ther
; 32(6): 1600-1601, 2024 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38788709
8.
mRNA Therapy Improves Metabolic and Behavioral Abnormalities in a Murine Model of Citrin Deficiency.
Mol Ther
; 27(7): 1242-1251, 2019 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31056400
9.
The Nobel Prize awarded to pioneers of mRNA vaccines.
Mol Ther
; 31(11): 3105-3106, 2023 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37863063
10.
EphA2 receptor is a key player in the metastatic onset of Ewing sarcoma.
Int J Cancer
; 143(5): 1188-1201, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29582409
11.
AFBI assay - Aptamer Fluorescence Binding and Internalization assay for cultured adherent cells.
Methods
; 103: 180-7, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26972784
12.
Oligonucleotide aptamers: A next-generation technology for the capture and detection of circulating tumor cells.
Methods
; 97: 94-103, 2016 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26631715
13.
Analyzing HT-SELEX data with the Galaxy Project tools--A web based bioinformatics platform for biomedical research.
Methods
; 97: 3-10, 2016 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26481156
14.
Structural computational modeling of RNA aptamers.
Methods
; 103: 175-9, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26972787
15.
In vitro RNA SELEX for the generation of chemically-optimized therapeutic RNA drugs.
Methods
; 103: 167-74, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26972786
16.
Smooth Muscle Cell-targeted RNA Aptamer Inhibits Neointimal Formation.
Mol Ther
; 24(4): 779-87, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26732878
17.
Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decay.
Nature
; 465(7295): 227-30, 2010 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-20463739
18.
Multifunctional aptamer-miRNA conjugates for targeted cancer therapy.
Mol Ther
; 22(6): 1151-1163, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24441398
19.
Targeted inhibition of prostate cancer metastases with an RNA aptamer to prostate-specific membrane antigen.
Mol Ther
; 22(11): 1910-22, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24954476
20.
Delivery of chemo-sensitizing siRNAs to HER2+-breast cancer cells using RNA aptamers.
Nucleic Acids Res
; 40(13): 6319-37, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22467215