Detalhe da pesquisa
1.
Androgen receptor nuclear localization correlates with AR-V7 mRNA expression in circulating tumor cells (CTCs) from metastatic castration resistance prostate cancer patients.
Phys Biol
; 16(3): 036003, 2019 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30763921
2.
NAD+ and SIRT3 control microtubule dynamics and reduce susceptibility to antimicrotubule agents.
Proc Natl Acad Sci U S A
; 111(24): E2443-52, 2014 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24889606
3.
Microtubules regulate hypoxia-inducible factor-1α protein trafficking and activity: implications for taxane therapy.
J Biol Chem
; 287(15): 11859-69, 2012 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22367210
4.
The beta 1 tubulin R307H single nucleotide polymorphism is associated with treatment failures in immune thrombocytopenia (ITP).
Br J Haematol
; 160(2): 237-43, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23157319
5.
2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF.
Cancer Cell
; 3(4): 363-75, 2003 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-12726862
6.
RABbing cancer the wrong way.
Proc Natl Acad Sci U S A
; 111(31): 11230-1, 2014 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25053807
7.
AR-V7 exhibits non-canonical mechanisms of nuclear import and chromatin engagement in castrate-resistant prostate cancer.
Elife
; 112022 07 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35848798
8.
Farnesyl transferase expression determines clinical response to the docetaxel-lonafarnib combination in patients with advanced malignancies.
Cancer
; 117(17): 4049-59, 2011 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21365629
9.
Circulating Tumor Cell Genomic Evolution and Hormone Therapy Outcomes in Men with Metastatic Castration-Resistant Prostate Cancer.
Mol Cancer Res
; 19(6): 1040-1050, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33771885
10.
Androgen receptor variant shows heterogeneous expression in prostate cancer according to differentiation stage.
Commun Biol
; 4(1): 785, 2021 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34168263
11.
CLIP-170S is a microtubule +TIP variant that confers resistance to taxanes by impairing drug-target engagement.
Dev Cell
; 56(23): 3264-3275.e7, 2021 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34672971
12.
Circulating Tumor Cell Chromosomal Instability and Neuroendocrine Phenotype by Immunomorphology and Poor Outcomes in Men with mCRPC Treated with Abiraterone or Enzalutamide.
Clin Cancer Res
; 27(14): 4077-4088, 2021 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33820782
13.
Capture of circulating tumor cells from whole blood of prostate cancer patients using geometrically enhanced differential immunocapture (GEDI) and a prostate-specific antibody.
Lab Chip
; 10(1): 27-9, 2010 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-20024046
14.
Quantitative analysis of taxane drug target engagement of microtubules in circulating tumor cells from metastatic castration resistant prostate cancer patients treated with CRXL301, a nanoparticle of docetaxel.
Cancer Drug Resist
; 3: 636-646, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33062959
15.
Microtubule Engagement with Taxane Is Altered in Taxane-Resistant Gastric Cancer.
Clin Cancer Res
; 26(14): 3771-3783, 2020 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32321717
16.
Taxane resistance in prostate cancer is mediated by decreased drug-target engagement.
J Clin Invest
; 130(6): 3287-3298, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32478682
17.
Prospective Multicenter Study of Circulating Tumor Cell AR-V7 and Taxane Versus Hormonal Treatment Outcomes in Metastatic Castration-Resistant Prostate Cancer.
JCO Precis Oncol
; 42020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33154984
18.
Multicenter Phase II Study of Cabazitaxel in Advanced Gastroesophageal Cancer: Association of HER2 Expression and M2-Like Tumor-Associated Macrophages with Patient Outcome.
Clin Cancer Res
; 26(18): 4756-4766, 2020 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32641434
19.
A Bayesian machine learning approach for drug target identification using diverse data types.
Nat Commun
; 10(1): 5221, 2019 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31745082
20.
Expression of AR-V7 and ARv567es in Circulating Tumor Cells Correlates with Outcomes to Taxane Therapy in Men with Metastatic Prostate Cancer Treated in TAXYNERGY.
Clin Cancer Res
; 25(6): 1880-1888, 2019 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30301829