Detalhe da pesquisa
1.
A Novel NAMPT Inhibitor-Based Antibody-Drug Conjugate Payload Class for Cancer Therapy.
Bioconjug Chem
; 33(6): 1210-1221, 2022 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35658441
2.
Predictive Modeling of PROTAC Cell Permeability with Machine Learning.
ACS Omega
; 8(6): 5901-5916, 2023 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36816707
3.
Linker-Dependent Folding Rationalizes PROTAC Cell Permeability.
J Med Chem
; 65(19): 13029-13040, 2022 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36170570
4.
Inflammatory activation of surface molecule shedding by upregulation of the pseudoprotease iRhom2 in colon epithelial cells.
Sci Rep
; 11(1): 24230, 2021 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34930929
5.
Solution Conformations Shed Light on PROTAC Cell Permeability.
ACS Med Chem Lett
; 12(1): 107-114, 2021 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33488971
6.
Differential Induction of the ADAM17 Regulators iRhom1 and 2 in Endothelial Cells.
Front Cardiovasc Med
; 7: 610344, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33335915
7.
Status update on iRhom and ADAM17: It's still complicated.
Biochim Biophys Acta Mol Cell Res
; 1866(10): 1567-1583, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31330158
8.
Creation of a Novel Class of Potent and Selective MutT Homologue 1 (MTH1) Inhibitors Using Fragment-Based Screening and Structure-Based Drug Design.
J Med Chem
; 61(6): 2533-2551, 2018 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29485874
9.
Novel Class of Potent and Cellularly Active Inhibitors Devalidates MTH1 as Broad-Spectrum Cancer Target.
ACS Chem Biol
; 12(8): 1986-1992, 2017 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28679043
10.
Deletion of the LIME adaptor protein minimally affects T and B cell development and function.
Eur J Immunol
; 37(11): 3259-69, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17918199
11.
Inhibition of the growth of Toxoplasma gondii in immature human dendritic cells is dependent on the expression of TNF-alpha receptor 2.
J Immunol
; 173(5): 3366-74, 2004 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15322200