Detalhe da pesquisa
1.
Discovery of a Potent BTK Inhibitor with a Novel Binding Mode by Using Parallel Selections with a DNA-Encoded Chemical Library.
Chembiochem
; 18(9): 864-871, 2017 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28056160
2.
Discovery of Small Molecule Interleukin 17A Inhibitors with Novel Binding Mode and Stoichiometry: Optimization of DNA-Encoded Chemical Library Hits to In Vivo Active Compounds.
J Med Chem
; 67(8): 6456-6494, 2024 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38574366
3.
Corrigendum: Discovery of a Potent BTK Inhibitor with a Novel Binding Mode by Using Parallel Selections with a DNAEncoded Chemical Library.
Chembiochem
; 18(24): 2441, 2017 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29239533
4.
Uptake, efficacy, and systemic distribution of naked, inhaled short interfering RNA (siRNA) and locked nucleic acid (LNA) antisense.
Mol Ther
; 19(12): 2163-8, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21971426
5.
Bispecific Estrogen Receptor α Degraders Incorporating Novel Binders Identified Using DNA-Encoded Chemical Library Screening.
J Med Chem
; 64(8): 5049-5066, 2021 04 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33844532
6.
Generating Selective Leads for Mer Kinase Inhibitors-Example of a Comprehensive Lead-Generation Strategy.
J Med Chem
; 64(6): 3165-3184, 2021 03 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33683117
7.
Machine Learning on DNA-Encoded Libraries: A New Paradigm for Hit Finding.
J Med Chem
; 63(16): 8857-8866, 2020 08 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32525674
8.
Encoded Library Synthesis Using Chemical Ligation and the Discovery of sEH Inhibitors from a 334-Million Member Library.
Sci Rep
; 5: 10916, 2015 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26061191
9.
The design, synthesis and potential utility of fluorescence probes that target DFG-out conformation of p38alpha for high throughput screening binding assay.
Chem Biol Drug Des
; 74(6): 547-59, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19843080