Detalhe da pesquisa
1.
The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade.
Immunity
; 55(4): 671-685.e10, 2022 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35417675
2.
Traversing industry and academia in biomedicine: the best of both worlds?
Nat Rev Genet
; 23(8): 461-466, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35534711
3.
Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL.
Cell
; 150(3): 575-89, 2012 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22863010
4.
AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias.
Cell
; 146(5): 697-708, 2011 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-21884932
5.
Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells.
Cell
; 137(5): 821-34, 2009 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-19490892
6.
Unifying mechanism for different fibrotic diseases.
Proc Natl Acad Sci U S A
; 114(18): 4757-4762, 2017 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28424250
7.
Integrated genomic analysis illustrates the central role of JAK-STAT pathway activation in myeloproliferative neoplasm pathogenesis.
Blood
; 123(22): e123-33, 2014 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-24740812
8.
Kinase activation and transformation by NUP214-ABL1 is dependent on the context of the nuclear pore.
Mol Cell
; 31(1): 134-42, 2008 Jul 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-18614052
9.
Role of JAK2 in the pathogenesis and therapy of myeloproliferative disorders.
Nat Rev Cancer
; 7(9): 673-83, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17721432
10.
Niche-based screening identifies small-molecule inhibitors of leukemia stem cells.
Nat Chem Biol
; 9(12): 840-848, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24161946
11.
FLT3 mutations confer enhanced proliferation and survival properties to multipotent progenitors in a murine model of chronic myelomonocytic leukemia.
Cancer Cell
; 12(4): 367-80, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17936561
12.
FGFR3 activates RSK2 to mediate hematopoietic transformation through tyrosine phosphorylation of RSK2 and activation of the MEK/ERK pathway.
Cancer Cell
; 12(3): 201-14, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17785202
13.
Identification of driver and passenger mutations of FLT3 by high-throughput DNA sequence analysis and functional assessment of candidate alleles.
Cancer Cell
; 12(6): 501-13, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18068628
14.
Direct inhibition of the NOTCH transcription factor complex.
Nature
; 462(7270): 182-8, 2009 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-19907488
15.
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1.
Nature
; 462(7269): 108-12, 2009 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-19847166
16.
KIT with D816 mutations cooperates with CBFB-MYH11 for leukemogenesis in mice.
Blood
; 119(6): 1511-21, 2012 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-22160378
17.
Cell-autonomous and -nonautonomous contributions of STAT1 in murine models of tumorigenesis.
Cancer Cell
; 10(1): 1-2, 2006 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16843258
18.
Activating alleles of JAK3 in acute megakaryoblastic leukemia.
Cancer Cell
; 10(1): 65-75, 2006 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16843266
19.
Activating mutations in ALK provide a therapeutic target in neuroblastoma.
Nature
; 455(7215): 975-8, 2008 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-18923525
20.
Leukaemia stem cells and the evolution of cancer-stem-cell research.
Nat Rev Cancer
; 5(4): 311-21, 2005 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-15803157