Familial Influences on Neuroticism and Education in the UK Biobank.

Genome-wide studies often exclude family members, even though they are a valuable source of information. We identified parent-offspring pairs, siblings and couples in the UK Biobank and implemented a family-based DNA-derived heritability method to capture additional genetic effects and multiple sources of environmental influence on neuroticism and years of education. Compared to estimates from unrelated individuals, total heritability increased from 10 to 27% and from 17 to 56% for neuroticism and education respectively by including family-based genetic effects. We detected no family environmental influences on neuroticism. The couple similarity variance component explained 35% of the variation in years of education, probably reflecting assortative mating. Overall, our genetic and environmental estimates closely replicate previous findings from an independent sample. However, more research is required to dissect contributions to the additional heritability by rare and structural genetic effects, assortative mating, and residual environmental confounding. The latter is especially relevant for years of education, a highly socially contingent variable, for which our heritability estimate is at the upper end of twin estimates in the literature. Family-based genetic effects could be harnessed to improve polygenic prediction.

A Method for Catchment Scale Mapping of Groundwater-Dependent Ecosystems to Support Natural Resource Management (Queensland, Australia).

Immediate and foreseeable threats to groundwater-dependent ecosystems (GDEs) are widely acknowledged, many linked to altered groundwater regimes including changes in groundwater flow, flux, pressure, level and/or quality (Eamus et al. in Aust J Bot 54:97-114, 2006a). Natural resource managers and other decision-makers often lack sufficient information at an appropriate scale to understand the groundwater dependency of ecosystems and ensure that GDEs are adequately considered in decision-making processes. This paper describes a new catchment scale mapping method for GDEs based on the integration of local expert knowledge with detailed spatial datasets to delineate GDEs at a scale compatible with management and planning activities. This overcomes one of the key criticisms often levelled at broader scale mapping methods-that information from local and regional experts, with significant understanding of landscape processes and ecosystems, is not incorporated into the datasets used by decision-makers. Expert knowledge is conveyed in the form of pictorial conceptual models representing the components, processes and interrelationships of groundwater within a catchment and the ecosystems dependent on it. Each mapped GDE is linked to a pictorial conceptual model and a mapping rule-set to provide decision-makers with valuable information about where, how and why GDEs exist in a landscape.

Effects and significance of groundwater for vegetation: A systematic review.

Groundwater represents a critical water source for plants, especially during drought, with continuous groundwater availability widely associated with the presence of ecological refugia and the preservation of biodiversity during periods of adverse conditions. Here, we present a systematic quantitative literature review of global groundwater and ecosystem interactions to synthesise current knowledge and identify key knowledge gaps and research priorities through a management lens. Despite increasing research on groundwater dependent vegetation since the late 1990s, significant geographical and ecological biases are evident with papers focused on arid regions or areas with significant anthropogenic changes. Of the 140 papers reviewed, desert and steepe arid landscapes accounted for 50.7 % and desert and xeric shrublands were represented in 37.9 % of papers. A third of papers (34.4 %) quantified groundwater uptake by ecosystems and groundwater contributions to transpiration, with studies examining the influence of groundwater on vegetation productivity, distribution, and composition also well represented. In contrast, groundwater influences on other ecosystem functions are relatively poorly explored. The research biases introduce uncertainty in the transferability of findings between locations and ecosystems limiting the generality of our current understanding. This synthesis contributes to consolidating a solid knowledge base of the hydrological and ecological interrelationships for managers, planners, and other decision-makers that is relevant to the landscapes and environments they manage, so can more effectively deliver ecological and conservation outcomes.

A long-term follow-up of adolescent anorexia nervosa.

Twenty-one female patients between the ages of 15 and 44 years who had suffered from anorexia nervosa between the ages of 11 and 17 were re-evaluated at a mean follow-up of 9.4 years. The continuing psychic impairment of the former patients was apparent both in interviews and questionnaires. Abnormalities were found in 10 to 66% of the patients according to different symptoms and criteria. The outcome was less favourable for patients who had experienced a high initial weight loss and had been subjected to repeated in-patient treatment. Three variables were most significant in terms of poor long-term prognosis: pre-morbid obesity, pre-morbid eating disorders and complications during pregnancy.