Detalhe da pesquisa
1.
Increased CXCL4 expression in hematopoietic cells links inflammation and progression of bone marrow fibrosis in MPN.
Blood
; 136(18): 2051-2064, 2020 10 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32726410
2.
Still a burning question: the interplay between inflammation and fibrosis in myeloproliferative neoplasms.
Curr Opin Hematol
; 28(5): 364-371, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34232140
3.
Understanding deregulated cellular and molecular dynamics in the haematopoietic stem cell niche to develop novel therapeutics for bone marrow fibrosis.
J Pathol
; 245(2): 138-146, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29570794
4.
Macrophage enzyme and reduced inflammation drive brain correction of mucopolysaccharidosis IIIB by stem cell gene therapy.
Brain
; 141(1): 99-116, 2018 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29186350
5.
A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency.
Brain
; 141(7): 2014-2031, 2018 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29788236
6.
"ASXL1"-erating inflammation and bone marrow fibrosis in myeloproliferative neoplasms.
Haematologica
; 108(5): 1203-1204, 2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36005565
7.
Fusion of Rabies Virus Glycoprotein or gh625 to Iduronate-2-Sulfatase for the Treatment of Mucopolysaccharidosis Type II.
Hum Gene Ther
; 35(7-8): 232-242, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-37212263
8.
Collaborative effect of Csnk1a1 haploinsufficiency and mutant p53 in Myc induction can promote leukemic transformation.
Blood Adv
; 8(3): 766-779, 2024 02 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38147624
9.
Non-canonical Hedgehog signaling mediates profibrotic hematopoiesis-stroma crosstalk in myeloproliferative neoplasms.
Cell Rep
; 43(1): 113608, 2024 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38117649
10.
Sustained long-term disease correction in a murine model of MPSII following stem cell gene therapy.
Mol Ther Methods Clin Dev
; 31: 101127, 2023 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37920237
11.
Biological drivers of clinical phenotype in myelofibrosis.
Leukemia
; 37(2): 255-264, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36434065
12.
Genetic barcoding systematically compares genes in del(5q) MDS and reveals a central role for CSNK1A1 in clonal expansion.
Blood Adv
; 6(6): 1780-1796, 2022 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35016204
13.
Isolation of human bone marrow stromal cells from bone marrow biopsies for single-cell RNA sequencing.
STAR Protoc
; 2(2): 100538, 2021 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34027494
14.
Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis.
Cell Stem Cell
; 28(4): 637-652.e8, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33301706
15.
An Improved Adeno-Associated Virus Vector for Neurological Correction of the Mouse Model of Mucopolysaccharidosis IIIA.
Hum Gene Ther
; 30(9): 1052-1066, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31020862
16.
Brain-targeted stem cell gene therapy corrects mucopolysaccharidosis type II via multiple mechanisms.
EMBO Mol Med
; 10(7)2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29884617
17.
Identification of age-dependent motor and neuropsychological behavioural abnormalities in a mouse model of Mucopolysaccharidosis Type II.
PLoS One
; 12(2): e0172435, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28207863
18.
Fibrosis driving myofibroblast precursors in MPN and new therapeutic pathways.
Hemasphere
; 3(Suppl)2019 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35309783