Detalhe da pesquisa
1.
Phthalazinone-based lactams and cyclic ureas as ROCK2 selective inhibitors.
Bioorg Med Chem Lett
; 88: 129304, 2023 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37119973
2.
Discovery of a phenylpyrazole amide ROCK inhibitor as a tool molecule for in vivo studies.
Bioorg Med Chem Lett
; 30(21): 127495, 2020 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32798651
3.
Recent encounters with atropisomerism in drug discovery.
Bioorg Med Chem Lett
; 28(2): 53-60, 2018 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29223590
4.
Neutral macrocyclic factor VIIa inhibitors.
Bioorg Med Chem Lett
; 27(12): 2650-2654, 2017 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28460818
5.
Synthesis and P1' SAR exploration of potent macrocyclic tissue factor-factor VIIa inhibitors.
Bioorg Med Chem Lett
; 26(20): 5051-5057, 2016 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27612545
6.
Design and synthesis of potent, selective phenylimidazole-based FVIIa inhibitors.
Bioorg Med Chem Lett
; 25(10): 2169-73, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25881820
7.
Nonbenzamidine acylsulfonamide tissue factor-factor VIIa inhibitors.
Bioorg Med Chem Lett
; 23(18): 5244-8, 2013 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23845220
8.
Design and synthesis of bicyclic pyrazinone and pyrimidinone amides as potent TF-FVIIa inhibitors.
Bioorg Med Chem Lett
; 23(6): 1604-7, 2013 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23416003
9.
Atropisomer Control in Macrocyclic Factor VIIa Inhibitors.
J Med Chem
; 59(8): 4007-18, 2016 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27015008
10.
Discovery of a Highly Potent, Selective, and Orally Bioavailable Macrocyclic Inhibitor of Blood Coagulation Factor VIIa-Tissue Factor Complex.
J Med Chem
; 59(15): 7125-37, 2016 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27455395
11.
P2Y6 receptor potentiates pro-inflammatory responses in macrophages and exhibits differential roles in atherosclerotic lesion development.
PLoS One
; 9(10): e111385, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25360548
12.
Design and Synthesis of Phenylpyrrolidine Phenylglycinamides As Highly Potent and Selective TF-FVIIa Inhibitors.
ACS Med Chem Lett
; 5(2): 188-92, 2014 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900796
13.
Correction to "Atropisomer Control in Macrocyclic Factor VIIa Inhibitors".
J Med Chem
; 61(8): 3752, 2018 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29620363
14.
Design and synthesis of bicyclic pyrimidinone-based HCV NS3 protease inhibitors.
Bioorg Med Chem Lett
; 13(5): 785-8, 2003 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-12617891
15.
On the power of chemical synthesis: immunological evaluation of models for multiantigenic carbohydrate-based cancer vaccines.
Proc Natl Acad Sci U S A
; 99(21): 13699-704, 2002 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12359877
16.
Principles of mucin architecture: structural studies on synthetic glycopeptides bearing clustered mono-, di-, tri-, and hexasaccharide glycodomains.
J Am Chem Soc
; 124(33): 9833-44, 2002 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-12175243