Pesquisa | Portal de Pesquisa da BVS

1.

SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2.

Clausen, Thomas Mandel; Sandoval, Daniel R; Spliid, Charlotte B; Pihl, Jessica; Perrett, Hailee R; Painter, Chelsea D; Narayanan, Anoop; Majowicz, Sydney A; Kwong, Elizabeth M; McVicar, Rachael N; Thacker, Bryan E; Glass, Charles A; Yang, Zhang; Torres, Jonathan L; Golden, Gregory J; Bartels, Phillip L; Porell, Ryan N; Garretson, Aaron F; Laubach, Logan; Feldman, Jared; Yin, Xin; Pu, Yuan; Hauser, Blake M; Caradonna, Timothy M; Kellman, Benjamin P; Martino, Cameron; Gordts, Philip L S M; Chanda, Sumit K; Schmidt, Aaron G; Godula, Kamil; Leibel, Sandra L; Jose, Joyce; Corbett, Kevin D; Ward, Andrew B; Carlin, Aaron F; Esko, Jeffrey D.

Cell ; 183(4): 1043-1057.e15, 2020 11 12.

Artigo em Inglês | MEDLINE | ID: mdl-32970989

2.

Surface Sugars Get Cells in Shape.

Godula, Kamil.

Cell ; 177(7): 1672-1674, 2019 06 13.

Artigo em Inglês | MEDLINE | ID: mdl-31199912

3.

Glycocalyx engineering with heparan sulfate mimetics attenuates Wnt activity during adipogenesis to promote glucose uptake and metabolism.

Trieger, Greg W; Pessentheiner, Ariane R; Purcell, Sean C; Green, Courtney R; DeForest, Natalie; Willert, Karl; Majithia, Amit R; Metallo, Christian M; Godula, Kamil; Gordts, Philip L S M.

J Biol Chem ; 299(5): 104611, 2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-36931394

4.

Glycocalyx crowding with mucin mimetics strengthens binding of soluble and virus-associated lectins to host cell glycan receptors.

Honigfort, Daniel J; Altman, Meghan O; Gagneux, Pascal; Godula, Kamil.

Proc Natl Acad Sci U S A ; 118(40)2021 10 05.

Artigo em Inglês | MEDLINE | ID: mdl-34583992

5.

Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate.

Weiss, Ryan J; Spahn, Philipp N; Chiang, Austin W T; Liu, Qing; Li, Jing; Hamill, Kristina M; Rother, Sandra; Clausen, Thomas M; Hoeksema, Marten A; Timm, Bryce M; Godula, Kamil; Glass, Christopher K; Tor, Yitzhak; Gordts, Philip L S M; Lewis, Nathan E; Esko, Jeffrey D.

Nat Chem Biol ; 17(6): 684-692, 2021 06.

Artigo em Inglês | MEDLINE | ID: mdl-33846619

6.

The cancer glycocalyx mechanically primes integrin-mediated growth and survival.

Paszek, Matthew J; DuFort, Christopher C; Rossier, Olivier; Bainer, Russell; Mouw, Janna K; Godula, Kamil; Hudak, Jason E; Lakins, Jonathon N; Wijekoon, Amanda C; Cassereau, Luke; Rubashkin, Matthew G; Magbanua, Mark J; Thorn, Kurt S; Davidson, Michael W; Rugo, Hope S; Park, John W; Hammer, Daniel A; Giannone, Grégory; Bertozzi, Carolyn R; Weaver, Valerie M.

Nature ; 511(7509): 319-25, 2014 Jul 17.

Artigo em Inglês | MEDLINE | ID: mdl-25030168

7.

Efficient Synthesis of Heparinoid Bioconjugates for Tailoring FGF2 Activity at the Stem Cell-Matrix Interface.

Trieger, Greg W; Verespy, Stephen; Gordts, Philip L S M; Godula, Kamil.

Bioconjug Chem ; 30(3): 833-840, 2019 03 20.

Artigo em Inglês | MEDLINE | ID: mdl-30668905

8.

Small Molecule Antagonist of Cell Surface Glycosaminoglycans Restricts Mouse Embryonic Stem Cells in a Pluripotent State.

Huang, Mia L; Michalak, Austen L; Fisher, Christopher J; Christy, Mitchell; Smith, Raymond A A; Godula, Kamil.

Stem Cells ; 36(1): 45-54, 2018 01.

Artigo em Inglês | MEDLINE | ID: mdl-28984039

9.

Author Correction: Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate.

Weiss, Ryan J; Spahn, Philipp N; Chiang, Austin W T; Liu, Qing; Li, Jing; Hamill, Kristina M; Rother, Sandra; Clausen, Thomas M; Hoeksema, Marten A; Timm, Bryce M; Godula, Kamil; Glass, Christopher K; Tor, Yitzhak; Gordts, Philip L S M; Lewis, Nathan E; Esko, Jeffrey D.

Nat Chem Biol ; 18(5): 575, 2022 May.

Artigo em Inglês | MEDLINE | ID: mdl-35354934

10.

Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries.

Honigfort, Daniel J; Zhang, Michelle H; Verespy, Stephen; Godula, Kamil.

Faraday Discuss ; 219(0): 138-153, 2019 10 30.

Artigo em Inglês | MEDLINE | ID: mdl-31313786

11.

Human milk oligosaccharides inhibit growth of group B Streptococcus.

Lin, Ann E; Autran, Chloe A; Szyszka, Alexandra; Escajadillo, Tamara; Huang, Mia; Godula, Kamil; Prudden, Anthony R; Boons, Geert-Jan; Lewis, Amanda L; Doran, Kelly S; Nizet, Victor; Bode, Lars.

J Biol Chem ; 292(27): 11243-11249, 2017 07 07.

Artigo em Inglês | MEDLINE | ID: mdl-28416607

12.

Nanoscale materials for probing the biological functions of the glycocalyx.

Huang, Mia L; Godula, Kamil.

Glycobiology ; 26(8): 797-803, 2016 08.

Artigo em Inglês | MEDLINE | ID: mdl-26916883

13.

Following sugar patterns in search of galectin function.

Godula, Kamil.

Proc Natl Acad Sci U S A ; 115(11): 2548-2550, 2018 03 13.

Artigo em Inglês | MEDLINE | ID: mdl-29496962

14.

Glycocalyx remodeling with proteoglycan mimetics promotes neural specification in embryonic stem cells.

Huang, Mia L; Smith, Raymond A A; Trieger, Greg W; Godula, Kamil.

J Am Chem Soc ; 136(30): 10565-8, 2014 Jul 30.

Artigo em Inglês | MEDLINE | ID: mdl-25019314

15.

Chemoenzymatic Fc glycosylation via engineered aldehyde tags.

Smith, Elizabeth L; Giddens, John P; Iavarone, Anthony T; Godula, Kamil; Wang, Lai-Xi; Bertozzi, Carolyn R.

Bioconjug Chem ; 25(4): 788-95, 2014 Apr 16.

Artigo em Inglês | MEDLINE | ID: mdl-24702330

16.

Glycan interactions on glycocalyx mimetic surfaces: general discussion.

Azevedo, Helena S; Braunschweig, Adam B; Chiechi, Ryan C; Diaz Fernandez, Yuri; Gildersleeve, Jeffrey C; Godula, Kamil; Hartmann, Laura; Miura, Yoshiko; Schmidt, Stephan; Turnbull, W Bruce; Zhou, Dejian.

Faraday Discuss ; 219(0): 183-188, 2019 10 30.

Artigo em Inglês | MEDLINE | ID: mdl-31591625

17.

Preparation of multivalent glycan micro- and nano-arrays: general discussion.

Braunschweig, Adam; Byrne, Joseph P; Chiechi, Ryan; Diaz Fernandez, Yuri; Gildersleeve, Jeff; Godula, Kamil; Hartmann, Laura; Mahon, Clare; Miura, Yoshiko; Nelson, Alshakim; Schmidt, Stephan; Turnbull, W Bruce; Valles, Daniel; Yu, Jin; Zhou, Dejian.

Faraday Discuss ; 219(0): 128-137, 2019 10 30.

Artigo em Inglês | MEDLINE | ID: mdl-31560357

18.

Human extracellular sulfatases use a dual mechanism for regulation of growth factor interactions with heparan sulfate proteoglycans.

Timm, Bryce M; Follmar, Julianna L; Porell, Ryan N; Glass, Kimberly; Thacker, Bryan E; Glass, Charles A; Godula, Kamil.

bioRxiv ; 2023 Nov 22.

Artigo em Inglês | MEDLINE | ID: mdl-38045270

19.

Density variant glycan microarray for evaluating cross-linking of mucin-like glycoconjugates by lectins.

Godula, Kamil; Bertozzi, Carolyn R.

J Am Chem Soc ; 134(38): 15732-42, 2012 Sep 26.

Artigo em Inglês | MEDLINE | ID: mdl-22967056

20.

Stem Cell Microarrays for Assessing Growth Factor Signaling in Engineered Glycan Microenvironments.

Michalak, Austen L; Trieger, Greg W; Trieger, Kelsey A; Godula, Kamil.

Adv Healthc Mater ; 11(4): e2101232, 2022 02.

Artigo em Inglês | MEDLINE | ID: mdl-34541824

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